CRCGN010_HEPG2_24H:H18 Gene Set
Genes
52 genes differentially expressed following the CRCGN010_HEPG2_24H:H18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
STIMATE
|
STIM activating enhancer
|
8.17809
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
7.29387
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
5.66804
|
|
NR1H2
|
nuclear receptor subfamily 1, group H, member 2
|
4.91276
|
|
MOK
|
MOK protein kinase
|
4.65867
|
|
ATP11B
|
ATPase, class VI, type 11B
|
4.35252
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
4.34999
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
4.11637
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
4.11179
|
|
CCNA1
|
cyclin A1
|
3.87835
|
|
ZFP36
|
ZFP36 ring finger protein
|
3.24506
|
|
DYRK3
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
|
3.24011
|
|
SLC27A3
|
solute carrier family 27 (fatty acid transporter), member 3
|
2.89965
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
2.79222
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.72686
|
|
NMU
|
neuromedin U
|
2.71945
|
|
VGLL4
|
vestigial-like family member 4
|
2.66351
|
|
MMP1
|
matrix metallopeptidase 1
|
2.65289
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.3792
|
|
SMARCD2
|
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
|
2.35649
|
|
RPH3A
|
rabphilin 3A
|
2.11184
|
|
NLRP2B
|
NLR family pyrin domain containing 2B
|
2.10372
|
|
DDX10
|
DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
|
2.04946
|
|
EMC8
|
ER membrane protein complex subunit 8
|
2.0287
|
|
RXYLT1
|
ribitol xylosyltransferase 1
|
2.026
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-5.04629
|
|
LDHD
|
lactate dehydrogenase D
|
-5.00261
|
|
CCNB2
|
cyclin B2
|
-4.94473
|
|
CASP3
|
caspase 3, apoptosis-related cysteine peptidase
|
-4.77383
|
|
DNM1L
|
dynamin 1-like
|
-4.70671
|
|
CDC25B
|
cell division cycle 25B
|
-4.61191
|
|
FASTKD5
|
FAST kinase domains 5
|
-4.54353
|
|
UGDH
|
UDP-glucose 6-dehydrogenase
|
-4.29874
|
|
DNTTIP2
|
deoxynucleotidyltransferase, terminal, interacting protein 2
|
-4.27283
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-4.1222
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-3.85069
|
|
PCNA
|
proliferating cell nuclear antigen
|
-3.76108
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-3.72049
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
-3.3623
|
|
ZNF586
|
zinc finger protein 586
|
-3.3547
|
|
DUSP11
|
dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)
|
-3.08133
|
|
VDAC1
|
voltage-dependent anion channel 1
|
-2.88456
|
|
HYOU1
|
hypoxia up-regulated 1
|
-2.7354
|
|
PAEP
|
progestagen-associated endometrial protein
|
-2.4676
|
|
PPP1R26
|
protein phosphatase 1, regulatory subunit 26
|
-2.43177
|
|
RANBP2
|
RAN binding protein 2
|
-2.24229
|
|
PMCH
|
pro-melanin-concentrating hormone
|
-2.18858
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.16683
|
|
RAI14
|
retinoic acid induced 14
|
-2.08054
|
|
MIMS2
|
mitochondrial inner membrane scaffold 2
|
-2.06652
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.04052
|
|
MAD2L1BP
|
MAD2L1 binding protein
|
-2.02567
|
