| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | etodolac 20.0 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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81 genes differentially expressed following the CRCGN010_HEPG2_24H:H20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 9.28676 |
| AMDHD2 | amidohydrolase domain containing 2 | 5.12733 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 4.81843 |
| GSTZ1 | glutathione S-transferase zeta 1 | 4.74016 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 4.65134 |
| MYLK | myosin light chain kinase | 4.57363 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 4.52727 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit | 4.50756 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 4.4917 |
| UBQLN2 | ubiquilin 2 | 4.21261 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 4.06427 |
| ANO10 | anoctamin 10 | 3.93453 |
| TAC4 | tachykinin 4 (hemokinin) | 3.63293 |
| DIPK1A | divergent protein kinase domain 1A | 3.52261 |
| FZD7 | frizzled class receptor 7 | 3.38154 |
| MTPAP | mitochondrial poly(A) polymerase | 3.12601 |
| KDM5A | lysine (K)-specific demethylase 5A | 2.95792 |
| TSPAN6 | tetraspanin 6 | 2.63516 |
| ZFP36 | ZFP36 ring finger protein | 2.55741 |
| DDX42 | DEAD (Asp-Glu-Ala-Asp) box helicase 42 | 2.48389 |
| MKNK1 | MAP kinase interacting serine/threonine kinase 1 | 2.47183 |
| VGLL4 | vestigial-like family member 4 | 2.45163 |
| MCM3 | minichromosome maintenance complex component 3 | 2.40243 |
| LPAR2 | lysophosphatidic acid receptor 2 | 2.39748 |
| RFC5 | replication factor C (activator 1) 5, 36.5kDa | 2.39057 |
| HSPA8 | heat shock 70kDa protein 8 | 2.36146 |
| GSK3B | glycogen synthase kinase 3 beta | 2.29921 |
| PMM2 | phosphomannomutase 2 | 2.28492 |
| TEX10 | testis expressed 10 | 2.19225 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 2.09867 |
| RWDD2A | RWD domain containing 2A | 2.09723 |
| MCM10 | minichromosome maintenance complex component 10 | 2.09484 |
| IFT88 | intraflagellar transport 88 | 2.07607 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 2.05617 |
| HNRNPF | heterogeneous nuclear ribonucleoprotein F | 2.02475 |
| ERP29 | endoplasmic reticulum protein 29 | 2.02268 |
| BARD1 | BRCA1 associated RING domain 1 | 2.02255 |
| HSPA14 | heat shock 70kDa protein 14 | 2.02142 |
| PFKP | phosphofructokinase, platelet | 2.00015 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LDHD | lactate dehydrogenase D | -9.1924 |
| CCNB2 | cyclin B2 | -9.17389 |
| GNAS | GNAS complex locus | -7.02946 |
| GOLT1B | golgi transport 1B | -4.74704 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -4.72832 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -4.60845 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -4.42813 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | -4.39441 |
| DSG2 | desmoglein 2 | -4.36524 |
| SLC35F2 | solute carrier family 35, member F2 | -4.33358 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | -4.15477 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -4.04854 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -3.32641 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -3.29432 |
| ZNF586 | zinc finger protein 586 | -3.0724 |
| CBFA2T3 | core-binding factor, runt domain, alpha subunit 2; translocated to, 3 | -2.71348 |
| MAPK13 | mitogen-activated protein kinase 13 | -2.71258 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -2.69237 |
| DNMT1 | DNA (cytosine-5-)-methyltransferase 1 | -2.64246 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | -2.39135 |
| IL3 | interleukin 3 | -2.28928 |
| IAPP | islet amyloid polypeptide | -2.26887 |
| RFC2 | replication factor C (activator 1) 2, 40kDa | -2.26573 |
| EDN3 | endothelin 3 | -2.22507 |
| PDZD2 | PDZ domain containing 2 | -2.18694 |
| ADTRP | androgen-dependent TFPI-regulating protein | -2.18015 |
| SCNN1B | sodium channel, non voltage gated 1 beta subunit | -2.17105 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) | -2.14279 |
| TXNDC9 | thioredoxin domain containing 9 | -2.13761 |
| DIPK2B | divergent protein kinase domain 2B | -2.12535 |
| ITGB6 | integrin, beta 6 | -2.11934 |
| THSD4 | thrombospondin, type I, domain containing 4 | -2.1149 |
| PCBP3 | poly(rC) binding protein 3 | -2.10716 |
| RAB11FIP3 | RAB11 family interacting protein 3 (class II) | -2.10497 |
| PDS5A | PDS5 cohesin associated factor A | -2.10439 |
| TAPT1 | transmembrane anterior posterior transformation 1 | -2.08808 |
| PPOX | protoporphyrinogen oxidase | -2.07789 |
| H2BC17 | H2B clustered histone 17 | -2.07394 |
| PLA2G1B | phospholipase A2, group IB (pancreas) | -2.03781 |
| ECEL1 | endothelin converting enzyme-like 1 | -2.02304 |
| NIPSNAP3B | nipsnap homolog 3B (C. elegans) | -2.02268 |
| TCF12 | transcription factor 12 | -2.00511 |
