CRCGN010_HEPG2_24H:H21 Gene Set
Genes
55 genes differentially expressed following the CRCGN010_HEPG2_24H:H21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
EPN2
|
epsin 2
|
7.28946
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
6.59773
|
|
UBQLN2
|
ubiquilin 2
|
6.2762
|
|
MCOLN1
|
mucolipin 1
|
4.47917
|
|
CHN1
|
chimerin 1
|
4.31415
|
|
TATDN2
|
TatD DNase domain containing 2
|
4.30293
|
|
ATP11B
|
ATPase, class VI, type 11B
|
3.96827
|
|
CSK
|
c-src tyrosine kinase
|
3.85652
|
|
MYLK
|
myosin light chain kinase
|
3.78985
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
3.73808
|
|
LCN2
|
lipocalin 2
|
3.63647
|
|
LYN
|
LYN proto-oncogene, Src family tyrosine kinase
|
3.24644
|
|
LOC122526780
|
uncharacterized LOC122526780
|
3.15552
|
|
EVL
|
Enah/Vasp-like
|
3.00178
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
2.99624
|
|
CCNF
|
cyclin F
|
2.99556
|
|
FZD7
|
frizzled class receptor 7
|
2.97677
|
|
INTS3
|
integrator complex subunit 3
|
2.82598
|
|
CDC45
|
cell division cycle 45
|
2.73123
|
|
KDM5A
|
lysine (K)-specific demethylase 5A
|
2.67639
|
|
TREM1
|
triggering receptor expressed on myeloid cells 1
|
2.62533
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
2.59642
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
2.38997
|
|
CCNA1
|
cyclin A1
|
2.32071
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
2.29583
|
|
EPHA3
|
EPH receptor A3
|
2.28271
|
|
MAPK7
|
mitogen-activated protein kinase 7
|
2.21922
|
|
KLHL9
|
kelch-like family member 9
|
2.17068
|
|
PLSCR1
|
phospholipid scramblase 1
|
2.09613
|
|
JADE2
|
jade family PHD finger 2
|
2.06634
|
|
ACVR2B
|
activin A receptor, type IIB
|
2.02873
|
|
CUEDC1
|
CUE domain containing 1
|
2.02814
|
|
GPATCH8
|
G patch domain containing 8
|
2.01087
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ADI1
|
acireductone dioxygenase 1
|
-5.51778
|
|
ZDHHC6
|
zinc finger, DHHC-type containing 6
|
-4.42279
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-4.36029
|
|
COG7
|
component of oligomeric golgi complex 7
|
-4.09726
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-4.09689
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.04993
|
|
LDHD
|
lactate dehydrogenase D
|
-4.00516
|
|
NISCH
|
nischarin
|
-3.41817
|
|
DSG2
|
desmoglein 2
|
-3.34118
|
|
HACD3
|
3-hydroxyacyl-CoA dehydratase 3
|
-3.08441
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.86271
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-2.81242
|
|
CTNND1
|
catenin (cadherin-associated protein), delta 1
|
-2.77902
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.68257
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-2.67763
|
|
ZNF586
|
zinc finger protein 586
|
-2.58449
|
|
PEG10
|
paternally expressed 10
|
-2.51273
|
|
CHIC2
|
cysteine-rich hydrophobic domain 2
|
-2.48751
|
|
GDF15
|
growth differentiation factor 15
|
-2.29724
|
|
TIMELESS
|
timeless circadian clock
|
-2.29515
|
|
CYP11A1
|
cytochrome P450, family 11, subfamily A, polypeptide 1
|
-2.07196
|
|
TP53BP2
|
tumor protein p53 binding protein 2
|
-2.05167
|
