| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | etodolac 5.0 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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60 genes differentially expressed following the CRCGN010_HEPG2_24H:H22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 7.19171 |
| MOK | MOK protein kinase | 6.04376 |
| AMDHD2 | amidohydrolase domain containing 2 | 6.02541 |
| ATP11B | ATPase, class VI, type 11B | 5.18582 |
| NOTCH1 | notch 1 | 4.31288 |
| EPHB2 | EPH receptor B2 | 4.13615 |
| AGL | amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase | 4.11066 |
| DIPK1A | divergent protein kinase domain 1A | 3.94476 |
| PPARG | peroxisome proliferator-activated receptor gamma | 3.88263 |
| PRR15L | proline rich 15-like | 3.62101 |
| CSK | c-src tyrosine kinase | 3.48565 |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta | 3.39471 |
| SQOR | sulfide quinone oxidoreductase | 3.34717 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) | 3.28567 |
| EPN2 | epsin 2 | 3.21476 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 2.93498 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 2.9187 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | 2.90741 |
| LCN2 | lipocalin 2 | 2.78629 |
| CHMP6 | charged multivesicular body protein 6 | 2.69363 |
| ADGRG1 | adhesion G protein-coupled receptor G1 | 2.57876 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | 2.37775 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 2.37704 |
| DPEP1 | dipeptidase 1 (renal) | 2.27704 |
| NFATC4 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 | 2.25115 |
| E2F2 | E2F transcription factor 2 | 2.24792 |
| USP7 | ubiquitin specific peptidase 7 (herpes virus-associated) | 2.24289 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 2.22612 |
| GPER1 | G protein-coupled estrogen receptor 1 | 2.21229 |
| RNF43 | ring finger protein 43 | 2.17195 |
| PTCH2 | patched 2 | 2.09885 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 2.08847 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 2.07726 |
| TMSB4Y | thymosin beta 4, Y-linked | 2.06627 |
| FARP2 | FERM, RhoGEF and pleckstrin domain protein 2 | 2.04806 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CCNB2 | cyclin B2 | -5.47874 |
| FGFR4 | fibroblast growth factor receptor 4 | -5.21237 |
| GNAS | GNAS complex locus | -4.83976 |
| NRIP1 | nuclear receptor interacting protein 1 | -4.65164 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | -4.40066 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | -4.32873 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -4.28234 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -4.19268 |
| TUBB6 | tubulin, beta 6 class V | -4.17495 |
| TLR4 | toll-like receptor 4 | -4.16159 |
| CDC20 | cell division cycle 20 | -4.05938 |
| ISOC1 | isochorismatase domain containing 1 | -4.05855 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -4.00939 |
| LDHD | lactate dehydrogenase D | -3.86479 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -3.35841 |
| SLC35F2 | solute carrier family 35, member F2 | -2.72138 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -2.63528 |
| HSPB1 | heat shock 27kDa protein 1 | -2.57409 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -2.44728 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | -2.43945 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | -2.33139 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -2.27515 |
| SESN1 | sestrin 1 | -2.26927 |
| COG2 | component of oligomeric golgi complex 2 | -2.17946 |
| MAPK13 | mitogen-activated protein kinase 13 | -2.10973 |
