CRCGN010_HEPG2_24H:I01 Gene Set
Genes
48 genes differentially expressed following the CRCGN010_HEPG2_24H:I01 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
PMM2
|
phosphomannomutase 2
|
5.56992
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
5.04857
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
4.83467
|
|
ATP11B
|
ATPase, class VI, type 11B
|
4.78961
|
|
CYCS
|
cytochrome c, somatic
|
4.64405
|
|
CSK
|
c-src tyrosine kinase
|
4.09397
|
|
STK10
|
serine/threonine kinase 10
|
3.90208
|
|
MEST
|
mesoderm specific transcript
|
3.21521
|
|
PACSIN3
|
protein kinase C and casein kinase substrate in neurons 3
|
2.83528
|
|
ETS1
|
v-ets avian erythroblastosis virus E26 oncogene homolog 1
|
2.71825
|
|
NMU
|
neuromedin U
|
2.59973
|
|
HSPA8
|
heat shock 70kDa protein 8
|
2.46123
|
|
PSMB8
|
proteasome (prosome, macropain) subunit, beta type, 8
|
2.42462
|
|
JADE2
|
jade family PHD finger 2
|
2.3202
|
|
DCUN1D4
|
DCN1, defective in cullin neddylation 1, domain containing 4
|
2.28888
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.279
|
|
HPRT1
|
hypoxanthine phosphoribosyltransferase 1
|
2.04726
|
|
CUL1
|
cullin 1
|
2.04491
|
|
PLSCR3
|
phospholipid scramblase 3
|
2.01505
|
|
GPATCH8
|
G patch domain containing 8
|
2.01449
|
|
GADD45A
|
growth arrest and DNA-damage-inducible, alpha
|
2.00842
|
|
CCNF
|
cyclin F
|
2.00686
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-9.2378
|
|
CCNB2
|
cyclin B2
|
-8.34191
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-6.38179
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-6.00866
|
|
VAT1
|
vesicle amine transport 1
|
-5.06965
|
|
RNF167
|
ring finger protein 167
|
-4.69782
|
|
LDHD
|
lactate dehydrogenase D
|
-4.53101
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.19993
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-3.74918
|
|
IDH1
|
isocitrate dehydrogenase 1 (NADP+), soluble
|
-3.5281
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
-3.43381
|
|
ZNF586
|
zinc finger protein 586
|
-3.11949
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-2.96004
|
|
SCCPDH
|
saccharopine dehydrogenase (putative)
|
-2.7836
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.67603
|
|
WASHC4
|
WASH complex subunit 4
|
-2.5055
|
|
CCDC106
|
coiled-coil domain containing 106
|
-2.38346
|
|
SPACA9
|
sperm acrosome associated 9
|
-2.18564
|
|
TLR4
|
toll-like receptor 4
|
-2.16997
|
|
PPEF1
|
protein phosphatase, EF-hand calcium binding domain 1
|
-2.15975
|
|
HYOU1
|
hypoxia up-regulated 1
|
-2.13405
|
|
SLCO1C1
|
solute carrier organic anion transporter family, member 1C1
|
-2.07573
|
|
CCT5
|
chaperonin containing TCP1, subunit 5 (epsilon)
|
-2.06398
|
|
DKK4
|
dickkopf WNT signaling pathway inhibitor 4
|
-2.02761
|
|
RXRG
|
retinoid X receptor, gamma
|
-2.00919
|
|
CYB5R1
|
cytochrome b5 reductase 1
|
-2.00319
|
