CRCGN010_HEPG2_24H:I02 Gene Set
Genes
46 genes differentially expressed following the CRCGN010_HEPG2_24H:I02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
10.0
|
|
NOTCH1
|
notch 1
|
8.33446
|
|
MAP7
|
microtubule-associated protein 7
|
7.7248
|
|
UBQLN2
|
ubiquilin 2
|
5.11483
|
|
CHMP6
|
charged multivesicular body protein 6
|
5.07027
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
5.00097
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
4.89436
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
4.0358
|
|
PACSIN3
|
protein kinase C and casein kinase substrate in neurons 3
|
3.70445
|
|
TIMP2
|
TIMP metallopeptidase inhibitor 2
|
3.70066
|
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5
|
3.67838
|
|
CDPF1
|
cysteine-rich, DPF motif domain containing 1
|
3.48989
|
|
NR1H2
|
nuclear receptor subfamily 1, group H, member 2
|
3.43734
|
|
TBXA2R
|
thromboxane A2 receptor
|
3.39412
|
|
TREM1
|
triggering receptor expressed on myeloid cells 1
|
3.18339
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
3.1169
|
|
NMU
|
neuromedin U
|
2.88152
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
2.60385
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.57033
|
|
HBD
|
hemoglobin, delta
|
2.15823
|
|
CEL
|
carboxyl ester lipase
|
2.12122
|
|
LOC102724428
|
serine/threonine-protein kinase SIK1
|
2.04457
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-4.87045
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-4.80057
|
|
CCDC86
|
coiled-coil domain containing 86
|
-4.52177
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-4.00018
|
|
ISOC1
|
isochorismatase domain containing 1
|
-3.49531
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.48626
|
|
CD320
|
CD320 molecule
|
-3.43114
|
|
ZNF586
|
zinc finger protein 586
|
-3.42531
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.39167
|
|
RNF167
|
ring finger protein 167
|
-3.30198
|
|
ADI1
|
acireductone dioxygenase 1
|
-3.21769
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-2.90091
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.8991
|
|
SNX11
|
sorting nexin 11
|
-2.50774
|
|
IDH1
|
isocitrate dehydrogenase 1 (NADP+), soluble
|
-2.49918
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-2.29589
|
|
LRRN2
|
leucine rich repeat neuronal 2
|
-2.27485
|
|
GLOD4
|
glyoxalase domain containing 4
|
-2.24873
|
|
SPAG4
|
sperm associated antigen 4
|
-2.22365
|
|
CRY1
|
cryptochrome circadian clock 1
|
-2.16156
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.03858
|
|
CCDC69
|
coiled-coil domain containing 69
|
-2.02714
|
|
ALDH9A1
|
aldehyde dehydrogenase 9 family, member A1
|
-2.02534
|
|
LSM5
|
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
|
-2.00776
|
