| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | (4-chloro-2-methylphenoxy)acetic acid 5.44 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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101 genes differentially expressed following the CRCGN010_HEPG2_24H:I03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| UBQLN2 | ubiquilin 2 | 10.0 |
| CSK | c-src tyrosine kinase | 5.51131 |
| ABHD4 | abhydrolase domain containing 4 | 5.00169 |
| STIMATE | STIM activating enhancer | 4.77867 |
| RRAGA | Ras-related GTP binding A | 4.72838 |
| EVL | Enah/Vasp-like | 4.42491 |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | 4.39939 |
| NUP133 | nucleoporin 133kDa | 4.35493 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 4.11493 |
| GSTZ1 | glutathione S-transferase zeta 1 | 4.00545 |
| DIPK1A | divergent protein kinase domain 1A | 3.76119 |
| MAP7 | microtubule-associated protein 7 | 3.66975 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 3.66501 |
| MTERF3 | mitochondrial transcription termination factor 3 | 3.57019 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 3.52303 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 3.51003 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 | 3.41143 |
| CCL2 | chemokine (C-C motif) ligand 2 | 3.14623 |
| HYOU1 | hypoxia up-regulated 1 | 2.92058 |
| NFATC4 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 | 2.89537 |
| GARRE1 | granule associated Rac and RHOG effector 1 | 2.71284 |
| SLC75A1 | solute carrier family 75 member 1 | 2.66438 |
| PIK3R4 | phosphoinositide-3-kinase, regulatory subunit 4 | 2.6413 |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 | 2.59598 |
| PCDHB11 | protocadherin beta 11 | 2.57036 |
| ATP13A2 | ATPase type 13A2 | 2.56089 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 2.55057 |
| MARCKSL1 | MARCKS-like 1 | 2.4772 |
| FPGS | folylpolyglutamate synthase | 2.47423 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | 2.41666 |
| ADH5 | alcohol dehydrogenase 5 (class III), chi polypeptide | 2.39505 |
| DDX10 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 | 2.35221 |
| TEX10 | testis expressed 10 | 2.32998 |
| ECD | ecdysoneless homolog (Drosophila) | 2.29857 |
| RSU1 | Ras suppressor protein 1 | 2.29839 |
| PIGP | phosphatidylinositol glycan anchor biosynthesis, class P | 2.29145 |
| PDLIM1 | PDZ and LIM domain 1 | 2.2587 |
| CYCS | cytochrome c, somatic | 2.23296 |
| CEBPZ | CCAAT/enhancer binding protein (C/EBP), zeta | 2.21768 |
| CHN1 | chimerin 1 | 2.21745 |
| PGAM4 | phosphoglycerate mutase family member 4 | 2.13265 |
| HBA1 | hemoglobin, alpha 1 | 2.12188 |
| COPS4 | COP9 signalosome subunit 4 | 2.11838 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | 2.07475 |
| TRAM2 | translocation associated membrane protein 2 | 2.05424 |
| EXOC2 | exocyst complex component 2 | 2.02581 |
| LOC112694756 | uncharaterized LOC112694756 | 2.01537 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CCNB2 | cyclin B2 | -9.50208 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -8.4625 |
| KDM3A | lysine (K)-specific demethylase 3A | -5.5376 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -5.16031 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -5.11703 |
| C2CD5 | C2 calcium-dependent domain containing 5 | -4.85744 |
| CDC20 | cell division cycle 20 | -4.5876 |
| GOLT1B | golgi transport 1B | -4.58103 |
| TRIB3 | tribbles pseudokinase 3 | -4.55779 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | -4.44641 |
| DNM1L | dynamin 1-like | -4.25452 |
| ADI1 | acireductone dioxygenase 1 | -4.14633 |
| EIF5 | eukaryotic translation initiation factor 5 | -3.75388 |
| CTSD | cathepsin D | -3.47702 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -3.42862 |
| ACAA1 | acetyl-CoA acyltransferase 1 | -3.28598 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -3.14325 |
| TLR4 | toll-like receptor 4 | -2.81932 |
| CCDC91 | coiled-coil domain containing 91 | -2.77987 |
| RAB11FIP5 | RAB11 family interacting protein 5 (class I) | -2.7695 |
| ETNK1 | ethanolamine kinase 1 | -2.6572 |
| DCK | deoxycytidine kinase | -2.64016 |
| CMAS | cytidine monophosphate N-acetylneuraminic acid synthetase | -2.57131 |
| RECQL | RecQ helicase-like | -2.56221 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -2.48987 |
| TOPBP1 | topoisomerase (DNA) II binding protein 1 | -2.48053 |
| CAPN1 | calpain 1, (mu/I) large subunit | -2.46642 |
| NGRN | neugrin, neurite outgrowth associated | -2.44677 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.44046 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -2.34119 |
| PEG10 | paternally expressed 10 | -2.33855 |
| MED21 | mediator complex subunit 21 | -2.29082 |
| PCMT1 | protein-L-isoaspartate (D-aspartate) O-methyltransferase | -2.26368 |
| ARL4A | ADP-ribosylation factor-like 4A | -2.24693 |
| PPOX | protoporphyrinogen oxidase | -2.20639 |
| MMRN1 | multimerin 1 | -2.19603 |
| FAR2 | fatty acyl CoA reductase 2 | -2.17496 |
| WASHC4 | WASH complex subunit 4 | -2.16667 |
| ETV6 | ets variant 6 | -2.15415 |
| YARS2 | tyrosyl-tRNA synthetase 2, mitochondrial | -2.13397 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | -2.1266 |
| GDAP2 | ganglioside induced differentiation associated protein 2 | -2.11325 |
| ANKRD6 | ankyrin repeat domain 6 | -2.10991 |
| SLCO4C1 | solute carrier organic anion transporter family, member 4C1 | -2.10342 |
| TCN2 | transcobalamin II | -2.07565 |
| TRPV6 | transient receptor potential cation channel, subfamily V, member 6 | -2.0735 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | -2.06748 |
| HAUS2 | HAUS augmin-like complex, subunit 2 | -2.06233 |
| NR1H4 | nuclear receptor subfamily 1, group H, member 4 | -2.05365 |
| MNS1 | meiosis-specific nuclear structural 1 | -2.05298 |
| PYROXD1 | pyridine nucleotide-disulphide oxidoreductase domain 1 | -2.02566 |
| CAPRIN2 | caprin family member 2 | -2.02162 |
| TULP3 | tubby like protein 3 | -2.01661 |
| PARP6 | poly (ADP-ribose) polymerase family, member 6 | -2.01445 |
