CRCGN010_HEPG2_24H:I04 Gene Set
Genes
53 genes differentially expressed following the CRCGN010_HEPG2_24H:I04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
STIMATE
|
STIM activating enhancer
|
9.66048
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
8.56027
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
4.6696
|
|
SQOR
|
sulfide quinone oxidoreductase
|
4.49391
|
|
LCN2
|
lipocalin 2
|
4.44032
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
4.09553
|
|
E2F2
|
E2F transcription factor 2
|
3.91916
|
|
PRR15L
|
proline rich 15-like
|
3.83835
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
3.79653
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
3.70839
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
3.7047
|
|
MSRA
|
methionine sulfoxide reductase A
|
3.6679
|
|
HOXA10
|
homeobox A10
|
3.4584
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
3.40414
|
|
RPA3
|
replication protein A3, 14kDa
|
3.24193
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
3.18943
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
3.10443
|
|
ZNF589
|
zinc finger protein 589
|
3.01103
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
2.88478
|
|
GRWD1
|
glutamate-rich WD repeat containing 1
|
2.78519
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
2.77793
|
|
MNMIP1
|
manchette microtubule inner protein 1
|
2.42643
|
|
CXCL8
|
chemokine (C-X-C motif) ligand 8
|
2.38453
|
|
EGF
|
epidermal growth factor
|
2.31805
|
|
MCUR1
|
mitochondrial calcium uniporter regulator 1
|
2.29732
|
|
CXCL3
|
chemokine (C-X-C motif) ligand 3
|
2.20639
|
|
STAG3
|
stromal antigen 3
|
2.11071
|
|
VASH2
|
vasohibin 2
|
2.08982
|
|
EPHA3
|
EPH receptor A3
|
2.03377
|
|
EVL
|
Enah/Vasp-like
|
2.01904
|
|
SKIC8
|
SKI8 subunit of superkiller complex
|
2.01589
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
TLR4
|
toll-like receptor 4
|
-7.74579
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-5.26018
|
|
ELAC2
|
elaC ribonuclease Z 2
|
-5.13155
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-4.99039
|
|
COG2
|
component of oligomeric golgi complex 2
|
-4.81296
|
|
CDC20
|
cell division cycle 20
|
-4.76231
|
|
ADI1
|
acireductone dioxygenase 1
|
-4.72115
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-4.37466
|
|
DNM1L
|
dynamin 1-like
|
-4.28257
|
|
ZNF586
|
zinc finger protein 586
|
-4.21219
|
|
FAIM
|
Fas apoptotic inhibitory molecule
|
-3.9517
|
|
YME1L1
|
YME1-like 1 ATPase
|
-3.72399
|
|
FHL2
|
four and a half LIM domains 2
|
-2.67961
|
|
PLA2G15
|
phospholipase A2, group XV
|
-2.56306
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
-2.55405
|
|
TLE1
|
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
|
-2.53158
|
|
DCK
|
deoxycytidine kinase
|
-2.33166
|
|
WAC
|
WW domain containing adaptor with coiled-coil
|
-2.28815
|
|
TRAPPC6A
|
trafficking protein particle complex 6A
|
-2.13853
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-2.03954
|
|
RGPD2
|
RANBP2-like and GRIP domain containing 2
|
-2.02649
|
|
YTHDC1
|
YTH domain containing 1
|
-2.00712
|
