CRCGN010_HEPG2_24H:I05 Gene Set
Genes
53 genes differentially expressed following the CRCGN010_HEPG2_24H:I05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
6.97733
|
|
NOTCH1
|
notch 1
|
6.41159
|
|
LCN2
|
lipocalin 2
|
5.49481
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
4.62998
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
4.59079
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
4.53464
|
|
MAMLD1
|
mastermind-like domain containing 1
|
4.32241
|
|
MYLK
|
myosin light chain kinase
|
4.10894
|
|
FZD7
|
frizzled class receptor 7
|
3.91075
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
3.81529
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.67116
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
3.67066
|
|
ATP11B
|
ATPase, class VI, type 11B
|
3.5295
|
|
BZW2
|
basic leucine zipper and W2 domains 2
|
3.48614
|
|
CHN1
|
chimerin 1
|
3.25627
|
|
MCM3
|
minichromosome maintenance complex component 3
|
3.12291
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
3.0704
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.90195
|
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
2.64873
|
|
KLHL9
|
kelch-like family member 9
|
2.38456
|
|
GRWD1
|
glutamate-rich WD repeat containing 1
|
2.36093
|
|
DHDDS
|
dehydrodolichyl diphosphate synthase
|
2.18451
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.15939
|
|
BATF
|
basic leucine zipper transcription factor, ATF-like
|
2.09391
|
|
ADAM10
|
ADAM metallopeptidase domain 10
|
2.02005
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-7.94916
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-5.98026
|
|
GNAS
|
GNAS complex locus
|
-5.25374
|
|
POLR2I
|
polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
|
-4.95101
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-4.89068
|
|
CD320
|
CD320 molecule
|
-4.57927
|
|
RPIA
|
ribose 5-phosphate isomerase A
|
-4.49331
|
|
VAT1
|
vesicle amine transport 1
|
-4.42737
|
|
DNM1L
|
dynamin 1-like
|
-4.42707
|
|
GOLT1B
|
golgi transport 1B
|
-3.79138
|
|
PLEKHJ1
|
pleckstrin homology domain containing, family J member 1
|
-3.63299
|
|
FABP5
|
fatty acid binding protein 5 (psoriasis-associated)
|
-3.62429
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-3.5129
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.2518
|
|
ZNF586
|
zinc finger protein 586
|
-3.13575
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-3.06025
|
|
DNALI1
|
dynein, axonemal, light intermediate chain 1
|
-2.68906
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-2.65041
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.62287
|
|
TLR4
|
toll-like receptor 4
|
-2.57227
|
|
SRFBP1
|
serum response factor binding protein 1
|
-2.53275
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.48461
|
|
PEG10
|
paternally expressed 10
|
-2.42269
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.41449
|
|
PPOX
|
protoporphyrinogen oxidase
|
-2.3941
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.37016
|
|
RBM15B
|
RNA binding motif protein 15B
|
-2.19827
|
|
CRK
|
v-crk avian sarcoma virus CT10 oncogene homolog
|
-2.10415
|
