CRCGN010_HEPG2_24H:I06 Gene Set
Genes
61 genes differentially expressed following the CRCGN010_HEPG2_24H:I06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
GPER1
|
G protein-coupled estrogen receptor 1
|
5.73255
|
|
FOXO4
|
forkhead box O4
|
4.40426
|
|
E2F2
|
E2F transcription factor 2
|
4.30426
|
|
CHN1
|
chimerin 1
|
4.0949
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
3.67414
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
3.17211
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
3.11143
|
|
SMARCD2
|
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
|
2.85773
|
|
GPATCH8
|
G patch domain containing 8
|
2.80282
|
|
EVL
|
Enah/Vasp-like
|
2.74199
|
|
MEST
|
mesoderm specific transcript
|
2.72717
|
|
NMU
|
neuromedin U
|
2.5505
|
|
CCNA1
|
cyclin A1
|
2.50286
|
|
SPTAN1
|
spectrin, alpha, non-erythrocytic 1
|
2.39436
|
|
WIF1
|
WNT inhibitory factor 1
|
2.33023
|
|
TRAPPC4
|
trafficking protein particle complex 4
|
2.27858
|
|
NUCB2
|
nucleobindin 2
|
2.23202
|
|
CCNF
|
cyclin F
|
2.21048
|
|
SOCS2
|
suppressor of cytokine signaling 2
|
2.19824
|
|
DYRK3
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
|
2.13323
|
|
PHKA1
|
phosphorylase kinase, alpha 1 (muscle)
|
2.12529
|
|
TRIM9
|
tripartite motif containing 9
|
2.10245
|
|
GATA2
|
GATA binding protein 2
|
2.08896
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
2.08563
|
|
SLC24A3
|
solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
|
2.06849
|
|
KIZ
|
kizuna centrosomal protein
|
2.0654
|
|
TAC4
|
tachykinin 4 (hemokinin)
|
2.02866
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.01017
|
|
ELAVL3
|
ELAV like neuron-specific RNA binding protein 3
|
2.00559
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-8.7703
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-5.2832
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-4.97955
|
|
LDHD
|
lactate dehydrogenase D
|
-4.68946
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-4.63977
|
|
FAIM
|
Fas apoptotic inhibitory molecule
|
-4.62312
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.5143
|
|
NIT1
|
nitrilase 1
|
-4.44024
|
|
ZNF586
|
zinc finger protein 586
|
-4.29067
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-4.19517
|
|
GNAS
|
GNAS complex locus
|
-3.79964
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-3.79809
|
|
UBE3C
|
ubiquitin protein ligase E3C
|
-3.77012
|
|
WASHC4
|
WASH complex subunit 4
|
-3.676
|
|
ADI1
|
acireductone dioxygenase 1
|
-3.22985
|
|
RRP12
|
ribosomal RNA processing 12 homolog (S. cerevisiae)
|
-3.07385
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-3.02527
|
|
TLR4
|
toll-like receptor 4
|
-2.94901
|
|
SCAND1
|
SCAN domain containing 1
|
-2.92228
|
|
XPO7
|
exportin 7
|
-2.86241
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-2.81114
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.81029
|
|
YME1L1
|
YME1-like 1 ATPase
|
-2.7846
|
|
DERA
|
deoxyribose-phosphate aldolase (putative)
|
-2.31608
|
|
TWF2
|
twinfilin actin binding protein 2
|
-2.28104
|
|
RAI14
|
retinoic acid induced 14
|
-2.16382
|
|
KLF2
|
Kruppel-like factor 2
|
-2.15566
|
|
GLOD4
|
glyoxalase domain containing 4
|
-2.10821
|
|
SERPIND1
|
serpin peptidase inhibitor, clade D (heparin cofactor), member 1
|
-2.08676
|
|
PPP4R1
|
protein phosphatase 4, regulatory subunit 1
|
-2.06776
|
|
LYPLA2
|
lysophospholipase II
|
-2.04022
|
|
RHOT2
|
ras homolog family member T2
|
-2.00539
|
