| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | acetohexamide 5.24 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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65 genes differentially expressed following the CRCGN010_HEPG2_24H:I09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AMDHD2 | amidohydrolase domain containing 2 | 8.50273 |
| LCN2 | lipocalin 2 | 8.14011 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 5.34644 |
| BAMBI | BMP and activin membrane-bound inhibitor | 5.3075 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 4.89729 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 4.77663 |
| MSRA | methionine sulfoxide reductase A | 4.62362 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 4.56309 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 4.50878 |
| JADE2 | jade family PHD finger 2 | 4.24044 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit | 3.98433 |
| EVL | Enah/Vasp-like | 3.76382 |
| PPARG | peroxisome proliferator-activated receptor gamma | 3.71811 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 3.7112 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 3.47386 |
| STK10 | serine/threonine kinase 10 | 3.45782 |
| LAGE3 | L antigen family, member 3 | 3.28524 |
| SATB1 | SATB homeobox 1 | 3.28389 |
| STIMATE | STIM activating enhancer | 3.28114 |
| ABHD6 | abhydrolase domain containing 6 | 3.09358 |
| TRIM13 | tripartite motif containing 13 | 3.08555 |
| CHN1 | chimerin 1 | 3.00323 |
| LOC122526780 | uncharacterized LOC122526780 | 2.69286 |
| VPS28 | vacuolar protein sorting 28 homolog (S. cerevisiae) | 2.69138 |
| ATP11B | ATPase, class VI, type 11B | 2.68453 |
| CCNF | cyclin F | 2.61525 |
| GPER1 | G protein-coupled estrogen receptor 1 | 2.47206 |
| FCHO1 | FCH domain only 1 | 2.38242 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 2.20291 |
| BORA | bora, aurora kinase A activator | 2.20148 |
| BIRC2 | baculoviral IAP repeat containing 2 | 2.18509 |
| RBL1 | retinoblastoma-like 1 | 2.17279 |
| SPECC1L | sperm antigen with calponin homology and coiled-coil domains 1-like | 2.13419 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -6.22667 |
| CDC20 | cell division cycle 20 | -5.89674 |
| ADI1 | acireductone dioxygenase 1 | -5.89593 |
| PCNA | proliferating cell nuclear antigen | -5.44753 |
| CD320 | CD320 molecule | -4.70288 |
| CD58 | CD58 molecule | -4.36436 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -4.05169 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -3.9333 |
| VAT1 | vesicle amine transport 1 | -3.9279 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -3.88666 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -3.82941 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -3.62542 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | -3.53837 |
| FHL2 | four and a half LIM domains 2 | -3.19801 |
| RNF167 | ring finger protein 167 | -3.11371 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | -2.98032 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -2.92192 |
| MAPK13 | mitogen-activated protein kinase 13 | -2.75685 |
| RAI14 | retinoic acid induced 14 | -2.63248 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -2.59893 |
| ZW10 | zw10 kinetochore protein | -2.56948 |
| TCTN1 | tectonic family member 1 | -2.4763 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -2.41887 |
| WASHC4 | WASH complex subunit 4 | -2.39771 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -2.34564 |
| GNAS | GNAS complex locus | -2.3311 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.31678 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -2.23855 |
| DRAM1 | DNA-damage regulated autophagy modulator 1 | -2.1471 |
| HAND1 | heart and neural crest derivatives expressed 1 | -2.11332 |
| PRSS53 | protease, serine, 53 | -2.03297 |
| ENGASE | endo-beta-N-acetylglucosaminidase | -2.02749 |
