CRCGN010_HEPG2_24H:I10 Gene Set
Genes
39 genes differentially expressed following the CRCGN010_HEPG2_24H:I10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
6.70472
|
|
MSRA
|
methionine sulfoxide reductase A
|
4.99818
|
|
CSK
|
c-src tyrosine kinase
|
4.88528
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
4.73701
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
4.23734
|
|
MAP7
|
microtubule-associated protein 7
|
4.10763
|
|
PLS1
|
plastin 1
|
3.98153
|
|
JADE2
|
jade family PHD finger 2
|
3.7339
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
3.30959
|
|
NUCB2
|
nucleobindin 2
|
3.26277
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
3.19498
|
|
TGFBR2
|
transforming growth factor, beta receptor II (70/80kDa)
|
3.09889
|
|
GPATCH8
|
G patch domain containing 8
|
2.72313
|
|
PRR15L
|
proline rich 15-like
|
2.72297
|
|
FHL5
|
four and a half LIM domains 5
|
2.65029
|
|
NOTCH1
|
notch 1
|
2.59105
|
|
CHMP6
|
charged multivesicular body protein 6
|
2.53943
|
|
NR1H2
|
nuclear receptor subfamily 1, group H, member 2
|
2.48517
|
|
CHN1
|
chimerin 1
|
2.47262
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
2.41302
|
|
TIMM22
|
translocase of inner mitochondrial membrane 22 homolog (yeast)
|
2.35582
|
|
TLR4
|
toll-like receptor 4
|
2.34982
|
|
ZNF239
|
zinc finger protein 239
|
2.34279
|
|
STIMATE
|
STIM activating enhancer
|
2.34143
|
|
NXPE3
|
neurexophilin and PC-esterase domain family, member 3
|
2.02477
|
|
UFM1
|
ubiquitin-fold modifier 1
|
2.01736
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CCNB2
|
cyclin B2
|
-6.60081
|
|
ADI1
|
acireductone dioxygenase 1
|
-4.85432
|
|
LOC124907782
|
dual specificity protein phosphatase 22
|
-4.81301
|
|
RNF167
|
ring finger protein 167
|
-3.96077
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-3.87885
|
|
TLE1
|
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
|
-3.56243
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-3.00553
|
|
STAT1
|
signal transducer and activator of transcription 1, 91kDa
|
-2.67958
|
|
ICAM5
|
intercellular adhesion molecule 5, telencephalin
|
-2.26088
|
|
GOLT1B
|
golgi transport 1B
|
-2.15969
|
|
PLK1
|
polo-like kinase 1
|
-2.11892
|
|
IDH1
|
isocitrate dehydrogenase 1 (NADP+), soluble
|
-2.03251
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-2.0046
|