| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | acetohexamide 1.31 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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64 genes differentially expressed following the CRCGN010_HEPG2_24H:I11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AMDHD2 | amidohydrolase domain containing 2 | 6.24821 |
| CSK | c-src tyrosine kinase | 5.01286 |
| VGLL4 | vestigial-like family member 4 | 4.95879 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 4.77767 |
| STIMATE | STIM activating enhancer | 4.49388 |
| STAP2 | signal transducing adaptor family member 2 | 4.32795 |
| GPER1 | G protein-coupled estrogen receptor 1 | 3.56712 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 3.45303 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | 3.17272 |
| CHN1 | chimerin 1 | 3.11762 |
| PPARG | peroxisome proliferator-activated receptor gamma | 3.01722 |
| AGL | amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase | 2.89801 |
| RXYLT1 | ribitol xylosyltransferase 1 | 2.75125 |
| PRR15L | proline rich 15-like | 2.70685 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 2.70099 |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | 2.61851 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 2.37383 |
| SLC27A3 | solute carrier family 27 (fatty acid transporter), member 3 | 2.34321 |
| PGAM4 | phosphoglycerate mutase family member 4 | 2.33105 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | 2.3175 |
| LPAR2 | lysophosphatidic acid receptor 2 | 2.24423 |
| LSM2 | LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 2.23451 |
| FGGY | FGGY carbohydrate kinase domain containing | 2.22368 |
| PNKP | polynucleotide kinase 3'-phosphatase | 2.19766 |
| ZHX2 | zinc fingers and homeoboxes 2 | 2.14734 |
| GIN1 | gypsy retrotransposon integrase 1 | 2.14335 |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta | 2.13086 |
| CAND1 | cullin-associated and neddylation-dissociated 1 | 2.05491 |
| RLIG1 | RNA 5'-phosphate and 3'-OH ligase 1 | 2.05305 |
| PRKCH | protein kinase C, eta | 2.05254 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CCNB2 | cyclin B2 | -7.9976 |
| FBXL12 | F-box and leucine-rich repeat protein 12 | -7.95004 |
| KDM3A | lysine (K)-specific demethylase 3A | -7.92021 |
| GNAS | GNAS complex locus | -7.05384 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -5.32255 |
| PEG10 | paternally expressed 10 | -5.28653 |
| CDC20 | cell division cycle 20 | -5.13485 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -4.51885 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -4.38026 |
| LDHD | lactate dehydrogenase D | -4.32726 |
| TLR4 | toll-like receptor 4 | -4.1058 |
| PCNA | proliferating cell nuclear antigen | -4.06509 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -3.64453 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -3.46888 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -3.33884 |
| EIF5 | eukaryotic translation initiation factor 5 | -3.19007 |
| SLC35F2 | solute carrier family 35, member F2 | -3.11835 |
| DERA | deoxyribose-phosphate aldolase (putative) | -3.04735 |
| UGDH | UDP-glucose 6-dehydrogenase | -2.97894 |
| VDAC1 | voltage-dependent anion channel 1 | -2.96688 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | -2.95594 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | -2.69549 |
| CRELD2 | cysteine-rich with EGF-like domains 2 | -2.60717 |
| PPOX | protoporphyrinogen oxidase | -2.59294 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | -2.59048 |
| DNTTIP2 | deoxynucleotidyltransferase, terminal, interacting protein 2 | -2.54904 |
| NGRN | neugrin, neurite outgrowth associated | -2.54627 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -2.33665 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | -2.24798 |
| NCSTN | nicastrin | -2.12726 |
| TAF4B | TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa | -2.03422 |
| SNX11 | sorting nexin 11 | -2.0227 |
| TFG | TRK-fused gene | -2.02003 |
| LCT | lactase | -2.00117 |
