CRCGN010_HEPG2_24H:I12 Gene Set
Genes
54 genes differentially expressed following the CRCGN010_HEPG2_24H:I12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
5.30848
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
5.17332
|
|
RELB
|
v-rel avian reticuloendotheliosis viral oncogene homolog B
|
5.10325
|
|
UBQLN2
|
ubiquilin 2
|
5.03859
|
|
LCN2
|
lipocalin 2
|
4.85268
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
4.74446
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
4.72255
|
|
MAP7
|
microtubule-associated protein 7
|
4.63068
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
4.63024
|
|
CSK
|
c-src tyrosine kinase
|
4.21218
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
4.17556
|
|
STK10
|
serine/threonine kinase 10
|
3.5963
|
|
EPHA3
|
EPH receptor A3
|
3.51341
|
|
LOC122526780
|
uncharacterized LOC122526780
|
3.50402
|
|
TIMM22
|
translocase of inner mitochondrial membrane 22 homolog (yeast)
|
3.29399
|
|
PFKL
|
phosphofructokinase, liver
|
2.97644
|
|
CHEK2
|
checkpoint kinase 2
|
2.97284
|
|
UFM1
|
ubiquitin-fold modifier 1
|
2.92474
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
2.89959
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.85539
|
|
CEBPZ
|
CCAAT/enhancer binding protein (C/EBP), zeta
|
2.47241
|
|
SCRN1
|
secernin 1
|
2.41415
|
|
AUP1
|
ancient ubiquitous protein 1
|
2.36743
|
|
TPD52L2
|
tumor protein D52-like 2
|
2.31005
|
|
ARGLU1
|
arginine and glutamate rich 1
|
2.11867
|
|
GPATCH8
|
G patch domain containing 8
|
2.10458
|
|
NMU
|
neuromedin U
|
2.0515
|
|
RBKS
|
ribokinase
|
2.02076
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-9.28565
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-9.2413
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-5.24975
|
|
TRIB3
|
tribbles pseudokinase 3
|
-5.22133
|
|
RGS2
|
regulator of G-protein signaling 2
|
-4.94075
|
|
FASTKD5
|
FAST kinase domains 5
|
-4.91961
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-4.73238
|
|
ISOC1
|
isochorismatase domain containing 1
|
-4.40276
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-3.90921
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-3.73739
|
|
GNAS
|
GNAS complex locus
|
-3.58243
|
|
ZNF586
|
zinc finger protein 586
|
-3.45144
|
|
IDH1
|
isocitrate dehydrogenase 1 (NADP+), soluble
|
-3.45001
|
|
TM9SF3
|
transmembrane 9 superfamily member 3
|
-3.38099
|
|
TLR4
|
toll-like receptor 4
|
-2.99942
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.81718
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.72049
|
|
ZNF816
|
zinc finger protein 816
|
-2.19275
|
|
ZFPM2
|
zinc finger protein, FOG family member 2
|
-2.1687
|
|
TRIB1
|
tribbles pseudokinase 1
|
-2.14682
|
|
FIS1
|
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
|
-2.06456
|
|
RAP1GAP
|
RAP1 GTPase activating protein
|
-2.04779
|
|
KCTD3
|
potassium channel tetramerization domain containing 3
|
-2.04139
|
|
SCRIB
|
scribbled planar cell polarity protein
|
-2.03757
|
|
TNFSF11
|
tumor necrosis factor (ligand) superfamily, member 11
|
-2.01198
|
|
GLOD4
|
glyoxalase domain containing 4
|
-2.00069
|
