CRCGN010_HEPG2_24H:I14 Gene Set
Genes
42 genes differentially expressed following the CRCGN010_HEPG2_24H:I14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
LCN2
|
lipocalin 2
|
8.61876
|
|
MAP7
|
microtubule-associated protein 7
|
4.14865
|
|
RPL39L
|
ribosomal protein L39-like
|
3.85295
|
|
UBQLN2
|
ubiquilin 2
|
3.56393
|
|
PLS1
|
plastin 1
|
3.5282
|
|
CCNF
|
cyclin F
|
3.39878
|
|
NFATC4
|
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
|
3.33844
|
|
TREM1
|
triggering receptor expressed on myeloid cells 1
|
3.29155
|
|
KIFBP
|
kinesin family binding protein
|
3.22737
|
|
DYRK3
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
|
3.11938
|
|
MYLK
|
myosin light chain kinase
|
2.50426
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
2.46689
|
|
E2F2
|
E2F transcription factor 2
|
2.38268
|
|
SYNE2
|
spectrin repeat containing, nuclear envelope 2
|
2.37261
|
|
EPN2
|
epsin 2
|
2.23997
|
|
BAMBI
|
BMP and activin membrane-bound inhibitor
|
2.20485
|
|
AGL
|
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
|
2.18812
|
|
SRC
|
SRC proto-oncogene, non-receptor tyrosine kinase
|
2.14239
|
|
HDGFL3
|
HDGF like 3
|
2.05167
|
|
EGF
|
epidermal growth factor
|
2.04572
|
|
SH3GL1
|
SH3-domain GRB2-like 1
|
2.03254
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-7.21545
|
|
YME1L1
|
YME1-like 1 ATPase
|
-4.45977
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-4.09047
|
|
TMEM109
|
transmembrane protein 109
|
-3.64678
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-3.06175
|
|
ZDHHC6
|
zinc finger, DHHC-type containing 6
|
-3.01895
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.01224
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.99321
|
|
ITGB1BP1
|
integrin beta 1 binding protein 1
|
-2.95294
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-2.94491
|
|
DNM1L
|
dynamin 1-like
|
-2.86245
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-2.71188
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-2.63482
|
|
LDHD
|
lactate dehydrogenase D
|
-2.62369
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.54162
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
-2.4902
|
|
VAT1
|
vesicle amine transport 1
|
-2.38389
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-2.344
|
|
FAM32A
|
family with sequence similarity 32, member A
|
-2.13604
|
|
SNX11
|
sorting nexin 11
|
-2.07717
|
|
TM9SF3
|
transmembrane 9 superfamily member 3
|
-2.02265
|
