CRCGN010_HEPG2_24H:I18 Gene Set
Genes
53 genes differentially expressed following the CRCGN010_HEPG2_24H:I18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
BAMBI
|
BMP and activin membrane-bound inhibitor
|
6.92259
|
|
CASP2
|
caspase 2, apoptosis-related cysteine peptidase
|
4.72557
|
|
STAP2
|
signal transducing adaptor family member 2
|
4.11822
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
4.05217
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
4.02505
|
|
INTS3
|
integrator complex subunit 3
|
4.01423
|
|
CHMP6
|
charged multivesicular body protein 6
|
3.62081
|
|
UBQLN2
|
ubiquilin 2
|
3.61339
|
|
E2F2
|
E2F transcription factor 2
|
3.51832
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.34417
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
3.22186
|
|
SATB1
|
SATB homeobox 1
|
3.12262
|
|
MAP7
|
microtubule-associated protein 7
|
3.10838
|
|
MICALL1
|
MICAL-like 1
|
3.05816
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
2.88772
|
|
CHN1
|
chimerin 1
|
2.71506
|
|
ANO10
|
anoctamin 10
|
2.61045
|
|
CYCS
|
cytochrome c, somatic
|
2.57066
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.53279
|
|
MKNK1
|
MAP kinase interacting serine/threonine kinase 1
|
2.37369
|
|
RAB21
|
RAB21, member RAS oncogene family
|
2.35185
|
|
FZD7
|
frizzled class receptor 7
|
2.19484
|
|
SLC27A3
|
solute carrier family 27 (fatty acid transporter), member 3
|
2.13664
|
|
MCUR1
|
mitochondrial calcium uniporter regulator 1
|
2.07362
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
2.06538
|
|
PITX2
|
paired-like homeodomain 2
|
2.04523
|
|
BAX
|
BCL2-associated X protein
|
2.03623
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CCNB2
|
cyclin B2
|
-9.44107
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-6.58483
|
|
ZNF586
|
zinc finger protein 586
|
-5.24973
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-4.22444
|
|
CD320
|
CD320 molecule
|
-3.80786
|
|
ZDHHC6
|
zinc finger, DHHC-type containing 6
|
-3.58148
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-3.57504
|
|
ZW10
|
zw10 kinetochore protein
|
-3.55212
|
|
DNTTIP2
|
deoxynucleotidyltransferase, terminal, interacting protein 2
|
-3.16421
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-3.12602
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-3.11826
|
|
CDC20
|
cell division cycle 20
|
-2.95824
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.8522
|
|
RGS2
|
regulator of G-protein signaling 2
|
-2.78934
|
|
DDX3Y
|
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
|
-2.75498
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-2.69765
|
|
YTHDF1
|
YTH N(6)-methyladenosine RNA binding protein 1
|
-2.65076
|
|
VDAC1
|
voltage-dependent anion channel 1
|
-2.64331
|
|
IFRD2
|
interferon-related developmental regulator 2
|
-2.62464
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-2.60111
|
|
GNAS
|
GNAS complex locus
|
-2.53686
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-2.48518
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-2.29448
|
|
MST1R
|
macrophage stimulating 1 receptor
|
-2.29051
|
|
PPOX
|
protoporphyrinogen oxidase
|
-2.205
|
|
POLR2M
|
polymerase (RNA) II (DNA directed) polypeptide M
|
-2.20001
|
