CRCGN010_HEPG2_24H:I20 Gene Set
Genes
43 genes differentially expressed following the CRCGN010_HEPG2_24H:I20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CHMP6
|
charged multivesicular body protein 6
|
6.77115
|
|
LCN2
|
lipocalin 2
|
6.19647
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
4.9714
|
|
ST3GAL5
|
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
|
4.87537
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
4.5621
|
|
MEF2C
|
myocyte enhancer factor 2C
|
4.28181
|
|
CASP2
|
caspase 2, apoptosis-related cysteine peptidase
|
4.27431
|
|
PLSCR1
|
phospholipid scramblase 1
|
4.12017
|
|
LOC122526780
|
uncharacterized LOC122526780
|
3.3348
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
3.29135
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
3.15976
|
|
GPATCH8
|
G patch domain containing 8
|
2.99462
|
|
MAST2
|
microtubule associated serine/threonine kinase 2
|
2.96935
|
|
CHN1
|
chimerin 1
|
2.83051
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
2.74219
|
|
PLCB3
|
phospholipase C, beta 3 (phosphatidylinositol-specific)
|
2.58981
|
|
UBQLN2
|
ubiquilin 2
|
2.49508
|
|
UCKL1
|
uridine-cytidine kinase 1-like 1
|
2.49381
|
|
TCFL5
|
transcription factor-like 5 (basic helix-loop-helix)
|
2.1963
|
|
TPM3
|
tropomyosin 3
|
2.19334
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.1864
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
2.12178
|
|
DPY19L1
|
dpy-19-like 1 (C. elegans)
|
2.09398
|
|
APOBEC2
|
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
|
2.0766
|
|
EGF
|
epidermal growth factor
|
2.06101
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-5.44432
|
|
TIMM9
|
translocase of inner mitochondrial membrane 9 homolog (yeast)
|
-5.0
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-4.50034
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-4.1081
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.75003
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-3.20413
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.98928
|
|
CD320
|
CD320 molecule
|
-2.92019
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-2.77224
|
|
DNM1L
|
dynamin 1-like
|
-2.73081
|
|
HMG20B
|
high mobility group 20B
|
-2.56805
|
|
RNF167
|
ring finger protein 167
|
-2.49687
|
|
PEG10
|
paternally expressed 10
|
-2.44228
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.29484
|
|
ADI1
|
acireductone dioxygenase 1
|
-2.19649
|
|
TAGLN2
|
transgelin 2
|
-2.11279
|
|
PCNA
|
proliferating cell nuclear antigen
|
-2.10492
|
|
PCK2
|
phosphoenolpyruvate carboxykinase 2 (mitochondrial)
|
-2.08198
|
