CRCGN010_HEPG2_24H:I23 Gene Set
Genes
49 genes differentially expressed following the CRCGN010_HEPG2_24H:I23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
KLHL21
|
kelch-like family member 21
|
4.62703
|
|
STAP2
|
signal transducing adaptor family member 2
|
4.5267
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
4.52333
|
|
E2F2
|
E2F transcription factor 2
|
4.50033
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
4.37385
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
4.34566
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
4.0951
|
|
PMM2
|
phosphomannomutase 2
|
4.03286
|
|
CHEK2
|
checkpoint kinase 2
|
3.95224
|
|
HDGFL3
|
HDGF like 3
|
3.67743
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
3.55179
|
|
LYN
|
LYN proto-oncogene, Src family tyrosine kinase
|
3.4903
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
3.24183
|
|
CHN1
|
chimerin 1
|
3.2083
|
|
KIFBP
|
kinesin family binding protein
|
3.06376
|
|
BPHL
|
biphenyl hydrolase-like (serine hydrolase)
|
2.97856
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.7663
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
2.67502
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.61971
|
|
NMU
|
neuromedin U
|
2.43865
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
2.35706
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
2.23303
|
|
CBR3
|
carbonyl reductase 3
|
2.23223
|
|
CHMP6
|
charged multivesicular body protein 6
|
2.11208
|
|
EIF2AK3
|
eukaryotic translation initiation factor 2-alpha kinase 3
|
2.09649
|
|
DDX10
|
DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
|
2.08259
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ZNF586
|
zinc finger protein 586
|
-8.41951
|
|
LDHD
|
lactate dehydrogenase D
|
-5.23055
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-4.67408
|
|
CCNB1
|
cyclin B1
|
-4.65805
|
|
THAP11
|
THAP domain containing 11
|
-4.64872
|
|
LOC124907782
|
dual specificity protein phosphatase 22
|
-4.60894
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-3.75864
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-3.53219
|
|
TLCD3A
|
TLC domain containing 3A
|
-3.41881
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-3.3681
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-3.25513
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-3.10036
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-2.75552
|
|
SNX11
|
sorting nexin 11
|
-2.52881
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-2.44798
|
|
RBM15B
|
RNA binding motif protein 15B
|
-2.41403
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-2.40514
|
|
CCNB2
|
cyclin B2
|
-2.32443
|
|
DNTTIP2
|
deoxynucleotidyltransferase, terminal, interacting protein 2
|
-2.22564
|
|
FOS
|
FBJ murine osteosarcoma viral oncogene homolog
|
-2.21778
|
|
TCFL5
|
transcription factor-like 5 (basic helix-loop-helix)
|
-2.2089
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.12983
|
|
PCK2
|
phosphoenolpyruvate carboxykinase 2 (mitochondrial)
|
-2.08993
|
