CRCGN010_HEPG2_24H:J01 Gene Set
Genes
44 genes differentially expressed following the CRCGN010_HEPG2_24H:J01 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
4.98115
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
4.8179
|
|
NMU
|
neuromedin U
|
3.86353
|
|
ABHD6
|
abhydrolase domain containing 6
|
3.67587
|
|
HMOX1
|
heme oxygenase 1
|
3.34689
|
|
HSPA8
|
heat shock 70kDa protein 8
|
3.27936
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
3.13014
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
3.12851
|
|
TATDN2
|
TatD DNase domain containing 2
|
3.06936
|
|
MEST
|
mesoderm specific transcript
|
3.05052
|
|
CHN1
|
chimerin 1
|
2.99414
|
|
ZNF589
|
zinc finger protein 589
|
2.92801
|
|
KLHL9
|
kelch-like family member 9
|
2.71142
|
|
MEF2C
|
myocyte enhancer factor 2C
|
2.68668
|
|
CCNF
|
cyclin F
|
2.64708
|
|
NOTCH1
|
notch 1
|
2.50683
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
2.50662
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
2.45614
|
|
GARRE1
|
granule associated Rac and RHOG effector 1
|
2.34054
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
2.33408
|
|
MAP7
|
microtubule-associated protein 7
|
2.31023
|
|
MYLK
|
myosin light chain kinase
|
2.22434
|
|
GFOD1
|
glucose-fructose oxidoreductase domain containing 1
|
2.14951
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
2.14684
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.08612
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
2.07854
|
|
TOP2B
|
topoisomerase (DNA) II beta 180kDa
|
2.02706
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CCNB2
|
cyclin B2
|
-7.15449
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-5.06464
|
|
VAT1
|
vesicle amine transport 1
|
-4.88771
|
|
TLR4
|
toll-like receptor 4
|
-4.14661
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.84109
|
|
ZNF586
|
zinc finger protein 586
|
-3.36526
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-3.1934
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-2.90319
|
|
LDHD
|
lactate dehydrogenase D
|
-2.60445
|
|
NR2F6
|
nuclear receptor subfamily 2, group F, member 6
|
-2.5445
|
|
ZDHHC6
|
zinc finger, DHHC-type containing 6
|
-2.48877
|
|
TCFL5
|
transcription factor-like 5 (basic helix-loop-helix)
|
-2.42853
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
-2.36918
|
|
EDEM1
|
ER degradation enhancer, mannosidase alpha-like 1
|
-2.35715
|
|
DUSP6
|
dual specificity phosphatase 6
|
-2.26012
|
|
COG7
|
component of oligomeric golgi complex 7
|
-2.24787
|
|
CCDC86
|
coiled-coil domain containing 86
|
-2.12907
|
