CRCGN010_HEPG2_24H:J12 Gene Set
Genes
56 genes differentially expressed following the CRCGN010_HEPG2_24H:J12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
5.82629
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
4.55188
|
|
BZW2
|
basic leucine zipper and W2 domains 2
|
4.54858
|
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
4.39595
|
|
UBQLN2
|
ubiquilin 2
|
4.32501
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
4.10247
|
|
LCN2
|
lipocalin 2
|
4.08159
|
|
MYLK
|
myosin light chain kinase
|
3.96137
|
|
TREM1
|
triggering receptor expressed on myeloid cells 1
|
3.90453
|
|
STIMATE
|
STIM activating enhancer
|
3.88235
|
|
CBR3
|
carbonyl reductase 3
|
3.60199
|
|
AXIN1
|
axin 1
|
3.50692
|
|
MEST
|
mesoderm specific transcript
|
3.4268
|
|
IDE
|
insulin-degrading enzyme
|
3.0844
|
|
CRTAP
|
cartilage associated protein
|
3.07141
|
|
ADAM10
|
ADAM metallopeptidase domain 10
|
3.0248
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.91966
|
|
CCNF
|
cyclin F
|
2.68435
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.54695
|
|
EVL
|
Enah/Vasp-like
|
2.47908
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.46725
|
|
PRKCH
|
protein kinase C, eta
|
2.45351
|
|
SNCA
|
synuclein, alpha (non A4 component of amyloid precursor)
|
2.29986
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
2.29909
|
|
ADGRG1
|
adhesion G protein-coupled receptor G1
|
2.22951
|
|
PLSCR3
|
phospholipid scramblase 3
|
2.13738
|
|
ZNF589
|
zinc finger protein 589
|
2.11878
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-8.45968
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-6.10412
|
|
ZNF586
|
zinc finger protein 586
|
-5.00769
|
|
TP53BP2
|
tumor protein p53 binding protein 2
|
-4.58031
|
|
CCDC86
|
coiled-coil domain containing 86
|
-4.35322
|
|
CAB39
|
calcium binding protein 39
|
-4.15438
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-3.94791
|
|
LDHD
|
lactate dehydrogenase D
|
-3.92222
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-3.76545
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.68736
|
|
ZDHHC6
|
zinc finger, DHHC-type containing 6
|
-3.65773
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-3.46846
|
|
LOC124907782
|
dual specificity protein phosphatase 22
|
-3.28867
|
|
COG2
|
component of oligomeric golgi complex 2
|
-3.02956
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.94395
|
|
TLR4
|
toll-like receptor 4
|
-2.9117
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-2.81588
|
|
CRK
|
v-crk avian sarcoma virus CT10 oncogene homolog
|
-2.79175
|
|
RNF167
|
ring finger protein 167
|
-2.70882
|
|
EDEM1
|
ER degradation enhancer, mannosidase alpha-like 1
|
-2.57566
|
|
YME1L1
|
YME1-like 1 ATPase
|
-2.44731
|
|
CTSD
|
cathepsin D
|
-2.42414
|
|
VAT1
|
vesicle amine transport 1
|
-2.29653
|
|
NBPF3
|
neuroblastoma breakpoint family, member 3
|
-2.19631
|
|
ADI1
|
acireductone dioxygenase 1
|
-2.19301
|
|
ATP6V1D
|
ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
|
-2.1905
|
|
GNAS
|
GNAS complex locus
|
-2.14609
|
|
GDPD5
|
glycerophosphodiester phosphodiesterase domain containing 5
|
-2.04841
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.00418
|
