| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | DMSO perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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60 genes differentially expressed following the CRCGN010_HEPG2_24H:J14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 7.57258 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 4.90673 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 4.6181 |
| NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) | 4.25701 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 3.96424 |
| H2BC12 | H2B clustered histone 12 | 3.52153 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 3.46985 |
| MAP7 | microtubule-associated protein 7 | 3.2938 |
| STK10 | serine/threonine kinase 10 | 3.04486 |
| CEP57 | centrosomal protein 57kDa | 2.9465 |
| CYCS | cytochrome c, somatic | 2.93057 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 2.79395 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 2.77012 |
| AMDHD2 | amidohydrolase domain containing 2 | 2.70878 |
| PPARG | peroxisome proliferator-activated receptor gamma | 2.6308 |
| RRAGA | Ras-related GTP binding A | 2.5439 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | 2.46684 |
| EGF | epidermal growth factor | 2.41314 |
| E2F2 | E2F transcription factor 2 | 2.40871 |
| RPA3 | replication protein A3, 14kDa | 2.34155 |
| PNKP | polynucleotide kinase 3'-phosphatase | 2.28554 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 2.23322 |
| MKNK1 | MAP kinase interacting serine/threonine kinase 1 | 2.20301 |
| LARP7 | La ribonucleoprotein domain family, member 7 | 2.17806 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 2.16401 |
| YJU2B | YJU2 splicing factor homolog B | 2.08535 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 2.07241 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | 2.0609 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CCNB2 | cyclin B2 | -7.60666 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -7.58108 |
| TLR4 | toll-like receptor 4 | -6.0056 |
| CCDC86 | coiled-coil domain containing 86 | -5.05686 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -4.71934 |
| PEG10 | paternally expressed 10 | -4.47488 |
| RFC2 | replication factor C (activator 1) 2, 40kDa | -3.92002 |
| GDF15 | growth differentiation factor 15 | -3.82588 |
| GNAS | GNAS complex locus | -3.67701 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -3.54243 |
| VAT1 | vesicle amine transport 1 | -3.52613 |
| ZW10 | zw10 kinetochore protein | -3.04723 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -3.02787 |
| WASHC4 | WASH complex subunit 4 | -2.92519 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -2.91339 |
| IDH1 | isocitrate dehydrogenase 1 (NADP+), soluble | -2.71781 |
| RPN1 | ribophorin I | -2.57132 |
| SNX11 | sorting nexin 11 | -2.50066 |
| UGDH | UDP-glucose 6-dehydrogenase | -2.46121 |
| CASP3 | caspase 3, apoptosis-related cysteine peptidase | -2.39578 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -2.36149 |
| LDHD | lactate dehydrogenase D | -2.26172 |
| ISOC1 | isochorismatase domain containing 1 | -2.25582 |
| CEP112 | centrosomal protein 112kDa | -2.22089 |
| PRPF19 | pre-mRNA processing factor 19 | -2.17543 |
| MVP | major vault protein | -2.11185 |
| MRPS16 | mitochondrial ribosomal protein S16 | -2.09606 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -2.08895 |
| LOC105379278 | uncharacterized LOC105379278 | -2.05314 |
| RTN3 | reticulon 3 | -2.05056 |
| ITGB5 | integrin, beta 5 | -2.0412 |
| JPT1 | Jupiter microtubule associated homolog 1 | -2.0093 |
