CRCGN010_HEPG2_24H:J15 Gene Set
Genes
49 genes differentially expressed following the CRCGN010_HEPG2_24H:J15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
LCN2
|
lipocalin 2
|
6.68657
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
3.99714
|
|
ST3GAL5
|
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
|
3.89088
|
|
EVL
|
Enah/Vasp-like
|
3.58179
|
|
CSK
|
c-src tyrosine kinase
|
3.54834
|
|
UBQLN2
|
ubiquilin 2
|
3.52171
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
3.49284
|
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
3.36787
|
|
STAP2
|
signal transducing adaptor family member 2
|
3.25356
|
|
MEST
|
mesoderm specific transcript
|
3.21283
|
|
SQOR
|
sulfide quinone oxidoreductase
|
3.20715
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
2.98281
|
|
SYNE2
|
spectrin repeat containing, nuclear envelope 2
|
2.927
|
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
2.91674
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
2.90802
|
|
MMP2
|
matrix metallopeptidase 2
|
2.79133
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
2.70506
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.67486
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
2.65587
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.59646
|
|
PLS1
|
plastin 1
|
2.47149
|
|
PHKG2
|
phosphorylase kinase, gamma 2 (testis)
|
2.45912
|
|
GARRE1
|
granule associated Rac and RHOG effector 1
|
2.45446
|
|
BPHL
|
biphenyl hydrolase-like (serine hydrolase)
|
2.31551
|
|
ETS1
|
v-ets avian erythroblastosis virus E26 oncogene homolog 1
|
2.13635
|
|
FZD7
|
frizzled class receptor 7
|
2.06695
|
|
TGFBR2
|
transforming growth factor, beta receptor II (70/80kDa)
|
2.04656
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-6.72041
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-6.33746
|
|
TLR4
|
toll-like receptor 4
|
-5.9304
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-4.85572
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-3.33062
|
|
TLCD3A
|
TLC domain containing 3A
|
-3.30062
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-3.26262
|
|
DNM1L
|
dynamin 1-like
|
-3.19731
|
|
PLK1
|
polo-like kinase 1
|
-3.14269
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-3.05671
|
|
PCNA
|
proliferating cell nuclear antigen
|
-3.03835
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-2.80826
|
|
PLEKHJ1
|
pleckstrin homology domain containing, family J member 1
|
-2.67576
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-2.52476
|
|
CDC20
|
cell division cycle 20
|
-2.41704
|
|
CASP3
|
caspase 3, apoptosis-related cysteine peptidase
|
-2.40381
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-2.36664
|
|
WASHC4
|
WASH complex subunit 4
|
-2.33314
|
|
ENOPH1
|
enolase-phosphatase 1
|
-2.30499
|
|
EDEM1
|
ER degradation enhancer, mannosidase alpha-like 1
|
-2.30295
|
|
STX4
|
syntaxin 4
|
-2.165
|
|
CHIC2
|
cysteine-rich hydrophobic domain 2
|
-2.06968
|
