| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 4-nitrosomorpholine 20.91 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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55 genes differentially expressed following the CRCGN010_HEPG2_24H:J19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 5.97128 |
| MAP7 | microtubule-associated protein 7 | 5.38984 |
| MAMLD1 | mastermind-like domain containing 1 | 4.00867 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 3.70245 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | 3.6648 |
| LCN2 | lipocalin 2 | 3.63406 |
| PPARG | peroxisome proliferator-activated receptor gamma | 3.51139 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 3.50517 |
| STIMATE | STIM activating enhancer | 3.44459 |
| EVL | Enah/Vasp-like | 3.30321 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | 3.21617 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 3.19428 |
| MYLK | myosin light chain kinase | 3.09365 |
| PEX11A | peroxisomal biogenesis factor 11 alpha | 3.00728 |
| CCL2 | chemokine (C-C motif) ligand 2 | 2.90147 |
| LOC122526780 | uncharacterized LOC122526780 | 2.80246 |
| RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 | 2.7792 |
| STXBP1 | syntaxin binding protein 1 | 2.54131 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 2.38078 |
| EPHA3 | EPH receptor A3 | 2.35818 |
| NUP133 | nucleoporin 133kDa | 2.34108 |
| PAF1 | Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) | 2.28141 |
| HSPA8 | heat shock 70kDa protein 8 | 2.21388 |
| NOSIP | nitric oxide synthase interacting protein | 2.21074 |
| HSPA1A | heat shock 70kDa protein 1A | 2.20513 |
| MICALL1 | MICAL-like 1 | 2.17518 |
| GPATCH8 | G patch domain containing 8 | 2.11083 |
| ADRB2 | adrenoceptor beta 2, surface | 2.09481 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 2.01067 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SLC35F2 | solute carrier family 35, member F2 | -4.62595 |
| TLR4 | toll-like receptor 4 | -4.1256 |
| WDR7 | WD repeat domain 7 | -4.002 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -3.95555 |
| ISOC1 | isochorismatase domain containing 1 | -3.84301 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -3.02594 |
| SLC25A13 | solute carrier family 25 (aspartate/glutamate carrier), member 13 | -2.95426 |
| COG2 | component of oligomeric golgi complex 2 | -2.90158 |
| GNAS | GNAS complex locus | -2.83461 |
| CD320 | CD320 molecule | -2.67667 |
| RAI14 | retinoic acid induced 14 | -2.6543 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -2.64156 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -2.56403 |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 | -2.45152 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -2.44618 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -2.41527 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -2.3998 |
| CCNB2 | cyclin B2 | -2.31781 |
| UGT2B4 | UDP glucuronosyltransferase 2 family, polypeptide B4 | -2.15444 |
| AQP9 | aquaporin 9 | -2.08381 |
| KDR | kinase insert domain receptor | -2.07671 |
| USP6NL | USP6 N-terminal like | -2.06621 |
| HMG20B | high mobility group 20B | -2.03013 |
| MMP2 | matrix metallopeptidase 2 | -2.02914 |
| GJA4 | gap junction protein, alpha 4, 37kDa | -2.02602 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | -2.00831 |
