CRCGN010_HEPG2_24H:J20 Gene Set
Genes
45 genes differentially expressed following the CRCGN010_HEPG2_24H:J20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
GSTZ1
|
glutathione S-transferase zeta 1
|
5.12407
|
|
LCN2
|
lipocalin 2
|
4.84939
|
|
MEST
|
mesoderm specific transcript
|
4.57465
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
4.38367
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
3.6032
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
3.2281
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
3.21005
|
|
ABHD6
|
abhydrolase domain containing 6
|
3.17472
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.97008
|
|
PPP1R13B
|
protein phosphatase 1, regulatory subunit 13B
|
2.90638
|
|
STK10
|
serine/threonine kinase 10
|
2.73452
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
2.65621
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.62268
|
|
LOC122526780
|
uncharacterized LOC122526780
|
2.55667
|
|
IDE
|
insulin-degrading enzyme
|
2.49073
|
|
GPATCH8
|
G patch domain containing 8
|
2.44655
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
2.33633
|
|
NMU
|
neuromedin U
|
2.3078
|
|
CHEK2
|
checkpoint kinase 2
|
2.28272
|
|
VAV3
|
vav 3 guanine nucleotide exchange factor
|
2.18324
|
|
MAP7
|
microtubule-associated protein 7
|
2.02951
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-4.94199
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.82451
|
|
HACD3
|
3-hydroxyacyl-CoA dehydratase 3
|
-4.15602
|
|
FASTKD5
|
FAST kinase domains 5
|
-3.43554
|
|
ITGB1BP1
|
integrin beta 1 binding protein 1
|
-3.43116
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-3.31327
|
|
ZDHHC6
|
zinc finger, DHHC-type containing 6
|
-3.21817
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-2.95201
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-2.91986
|
|
POLR2I
|
polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
|
-2.87886
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-2.81828
|
|
FOS
|
FBJ murine osteosarcoma viral oncogene homolog
|
-2.78162
|
|
PLK1
|
polo-like kinase 1
|
-2.76142
|
|
EDEM1
|
ER degradation enhancer, mannosidase alpha-like 1
|
-2.56956
|
|
CDK6
|
cyclin-dependent kinase 6
|
-2.49205
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-2.46521
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
-2.45183
|
|
DNM1L
|
dynamin 1-like
|
-2.19125
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-2.1767
|
|
CDC20
|
cell division cycle 20
|
-2.12859
|
|
ERO1A
|
endoplasmic reticulum oxidoreductase 1 alpha
|
-2.11133
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-2.0738
|
|
CCNB2
|
cyclin B2
|
-2.05867
|
|
FIS1
|
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
|
-2.02493
|
