| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 4-nitrosomorpholine 5.23 um perturbation at 24 h in HEPG2 (Carcinogenome) |
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70 genes differentially expressed following the CRCGN010_HEPG2_24H:J21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CHN1 | chimerin 1 | 6.05804 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 5.95732 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 5.67288 |
| MEST | mesoderm specific transcript | 5.30127 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 5.10276 |
| CSK | c-src tyrosine kinase | 5.02155 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 4.77069 |
| PHKG2 | phosphorylase kinase, gamma 2 (testis) | 4.6077 |
| PNKP | polynucleotide kinase 3'-phosphatase | 4.45356 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 4.39982 |
| CYCS | cytochrome c, somatic | 4.13703 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 4.04819 |
| PPARG | peroxisome proliferator-activated receptor gamma | 3.86843 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 3.73934 |
| MAMLD1 | mastermind-like domain containing 1 | 3.71337 |
| MCOLN1 | mucolipin 1 | 3.65346 |
| NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) | 3.58055 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 3.06427 |
| PFKL | phosphofructokinase, liver | 2.79106 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | 2.74406 |
| CCL2 | chemokine (C-C motif) ligand 2 | 2.73716 |
| CDC45 | cell division cycle 45 | 2.71511 |
| PIH1D1 | PIH1 domain containing 1 | 2.64448 |
| PLSCR1 | phospholipid scramblase 1 | 2.55437 |
| RXYLT1 | ribitol xylosyltransferase 1 | 2.55124 |
| UFM1 | ubiquitin-fold modifier 1 | 2.5283 |
| MX1 | MX dynamin-like GTPase 1 | 2.4278 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 2.42216 |
| GATA2 | GATA binding protein 2 | 2.3276 |
| PLSCR3 | phospholipid scramblase 3 | 2.32496 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 2.28215 |
| ZFP36 | ZFP36 ring finger protein | 2.27001 |
| GPATCH8 | G patch domain containing 8 | 2.19243 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 2.09323 |
| EVL | Enah/Vasp-like | 2.03389 |
| SMAGP | small cell adhesion glycoprotein | 2.00684 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -5.37948 |
| DERA | deoxyribose-phosphate aldolase (putative) | -4.80666 |
| TLR4 | toll-like receptor 4 | -4.73677 |
| CHMP4B | charged multivesicular body protein 4B | -4.17724 |
| TUBB6 | tubulin, beta 6 class V | -4.16525 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | -4.02636 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -3.87941 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -3.56399 |
| TLCD3A | TLC domain containing 3A | -3.47009 |
| EDEM1 | ER degradation enhancer, mannosidase alpha-like 1 | -3.34206 |
| FGFR4 | fibroblast growth factor receptor 4 | -3.09523 |
| CCNH | cyclin H | -3.00528 |
| SPAG4 | sperm associated antigen 4 | -2.68825 |
| MTA1 | metastasis associated 1 | -2.61309 |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) | -2.41741 |
| RBM34 | RNA binding motif protein 34 | -2.40346 |
| H2BC6 | H2B clustered histone 6 | -2.30173 |
| DPPA4 | developmental pluripotency associated 4 | -2.20417 |
| GAN | gigaxonin | -2.2038 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | -2.17795 |
| PANX1 | pannexin 1 | -2.17385 |
| GIN1 | gypsy retrotransposon integrase 1 | -2.17297 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -2.17096 |
| WDR46 | WD repeat domain 46 | -2.15592 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | -2.12849 |
| PPOX | protoporphyrinogen oxidase | -2.11007 |
| RBPMS | RNA binding protein with multiple splicing | -2.10988 |
| EPHA1 | EPH receptor A1 | -2.09461 |
| SEC14L4 | SEC14-like 4 (S. cerevisiae) | -2.05532 |
| FAM117A | family with sequence similarity 117, member A | -2.05188 |
| PRSS16 | protease, serine, 16 (thymus) | -2.04907 |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) | -2.03976 |
| COMMD10 | COMM domain containing 10 | -2.03556 |
| SCRT1 | scratch family zinc finger 1 | -2.02381 |
