CRCGN010_HEPG2_24H:J22 Gene Set
Genes
45 genes differentially expressed following the CRCGN010_HEPG2_24H:J22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
STIMATE
|
STIM activating enhancer
|
6.58465
|
|
MYLK
|
myosin light chain kinase
|
5.12606
|
|
CHMP6
|
charged multivesicular body protein 6
|
5.00691
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
4.90946
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
4.65554
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
4.26747
|
|
CASP2
|
caspase 2, apoptosis-related cysteine peptidase
|
4.24274
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
4.05192
|
|
CXCR4
|
chemokine (C-X-C motif) receptor 4
|
3.87304
|
|
SFTPB
|
surfactant protein B
|
3.62862
|
|
EVL
|
Enah/Vasp-like
|
3.3982
|
|
CHN1
|
chimerin 1
|
2.95648
|
|
MEST
|
mesoderm specific transcript
|
2.88465
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
2.63768
|
|
DCUN1D4
|
DCN1, defective in cullin neddylation 1, domain containing 4
|
2.60075
|
|
DYRK3
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
|
2.54784
|
|
LCN2
|
lipocalin 2
|
2.5381
|
|
HOXA10
|
homeobox A10
|
2.37625
|
|
AGL
|
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
|
2.30789
|
|
NKAPD1
|
NKAP domain containing 1
|
2.13053
|
|
APP
|
amyloid beta (A4) precursor protein
|
2.05638
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-6.11502
|
|
SLC25A13
|
solute carrier family 25 (aspartate/glutamate carrier), member 13
|
-5.09033
|
|
PCNA
|
proliferating cell nuclear antigen
|
-5.06593
|
|
CCNB1
|
cyclin B1
|
-4.85107
|
|
C2CD5
|
C2 calcium-dependent domain containing 5
|
-4.45623
|
|
ZNF586
|
zinc finger protein 586
|
-4.39665
|
|
CD320
|
CD320 molecule
|
-4.0973
|
|
VDAC1
|
voltage-dependent anion channel 1
|
-3.98009
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-3.80583
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.7696
|
|
UGDH
|
UDP-glucose 6-dehydrogenase
|
-3.63857
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-3.1362
|
|
LAP3
|
leucine aminopeptidase 3
|
-2.83698
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-2.62339
|
|
RRP12
|
ribosomal RNA processing 12 homolog (S. cerevisiae)
|
-2.57606
|
|
ITGB1BP1
|
integrin beta 1 binding protein 1
|
-2.3439
|
|
ETNK1
|
ethanolamine kinase 1
|
-2.33489
|
|
ALDH1A1
|
aldehyde dehydrogenase 1 family, member A1
|
-2.2693
|
|
CMAS
|
cytidine monophosphate N-acetylneuraminic acid synthetase
|
-2.20804
|
|
ASAH1
|
N-acylsphingosine amidohydrolase (acid ceramidase) 1
|
-2.20365
|
|
ADRA2C
|
adrenoceptor alpha 2C
|
-2.04901
|
|
PIK3C2G
|
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma
|
-2.0382
|
|
RBM15B
|
RNA binding motif protein 15B
|
-2.00249
|
|
GSTA1
|
glutathione S-transferase alpha 1
|
-2.00075
|
