| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 4-nitrosomorpholine 0.65 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
| Downloads & Tools |
58 genes differentially expressed following the CRCGN010_HEPG2_24H:J24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SFTPB | surfactant protein B | 5.83552 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 5.83405 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 5.48975 |
| MAMLD1 | mastermind-like domain containing 1 | 5.312 |
| PNKP | polynucleotide kinase 3'-phosphatase | 5.24165 |
| UBQLN2 | ubiquilin 2 | 5.07585 |
| LCN2 | lipocalin 2 | 5.0 |
| PPARG | peroxisome proliferator-activated receptor gamma | 4.9629 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | 4.84665 |
| RRAGA | Ras-related GTP binding A | 4.49715 |
| CHMP6 | charged multivesicular body protein 6 | 4.4517 |
| PRKCH | protein kinase C, eta | 4.43657 |
| PRR15L | proline rich 15-like | 3.84285 |
| SMAD3 | SMAD family member 3 | 3.76445 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 3.7292 |
| GSTZ1 | glutathione S-transferase zeta 1 | 3.46205 |
| CCL2 | chemokine (C-C motif) ligand 2 | 3.25865 |
| CHN1 | chimerin 1 | 3.1626 |
| DIPK1A | divergent protein kinase domain 1A | 3.07428 |
| CTSL | cathepsin L | 2.6079 |
| PARP2 | poly (ADP-ribose) polymerase 2 | 2.53793 |
| ERCC2 | excision repair cross-complementation group 2 | 2.50935 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 2.47855 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 2.31525 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | 2.2428 |
| HAX1 | HCLS1 associated protein X-1 | 2.09965 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | 2.0712 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -10.0 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | -5.80835 |
| TRIB3 | tribbles pseudokinase 3 | -4.85175 |
| CCDC86 | coiled-coil domain containing 86 | -4.80285 |
| LDHD | lactate dehydrogenase D | -4.74735 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -4.70845 |
| ADI1 | acireductone dioxygenase 1 | -4.66275 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -4.64373 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -4.51865 |
| PCNA | proliferating cell nuclear antigen | -4.25355 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -4.05175 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -3.9569 |
| ZNF586 | zinc finger protein 586 | -3.8122 |
| FGFR4 | fibroblast growth factor receptor 4 | -3.76113 |
| GNAS | GNAS complex locus | -3.64133 |
| TLR4 | toll-like receptor 4 | -3.63405 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -3.4237 |
| DBH | dopamine beta-hydroxylase (dopamine beta-monooxygenase) | -2.89385 |
| CAB39 | calcium binding protein 39 | -2.89295 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -2.72307 |
| PRPF4 | pre-mRNA processing factor 4 | -2.61573 |
| CHERP | calcium homeostasis endoplasmic reticulum protein | -2.43075 |
| IDH1 | isocitrate dehydrogenase 1 (NADP+), soluble | -2.32685 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -2.31293 |
| CHEK1 | checkpoint kinase 1 | -2.23345 |
| RBM34 | RNA binding motif protein 34 | -2.21467 |
| CREB5 | cAMP responsive element binding protein 5 | -2.20485 |
| IMPACT | impact RWD domain protein | -2.1689 |
| RSPH10B2 | radial spoke head 10 homolog B2 (Chlamydomonas) | -2.16495 |
| WDR82 | WD repeat domain 82 | -2.05175 |
| ZC3H3 | zinc finger CCCH-type containing 3 | -2.0375 |
