| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 1,2-dichlorobenzene 5.05 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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78 genes differentially expressed following the CRCGN010_HEPG2_24H:K04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ZNF589 | zinc finger protein 589 | 5.6365 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 5.34836 |
| PMM2 | phosphomannomutase 2 | 5.31383 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 4.91277 |
| CSK | c-src tyrosine kinase | 4.85748 |
| E2F2 | E2F transcription factor 2 | 4.72328 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | 4.6739 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 4.61273 |
| PRKCD | protein kinase C, delta | 4.58816 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) | 4.28733 |
| GSTZ1 | glutathione S-transferase zeta 1 | 4.11679 |
| PPARG | peroxisome proliferator-activated receptor gamma | 4.06868 |
| MAP7 | microtubule-associated protein 7 | 4.05977 |
| EDN1 | endothelin 1 | 3.90379 |
| NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) | 3.68174 |
| PRKCH | protein kinase C, eta | 3.65021 |
| ZFP36 | ZFP36 ring finger protein | 3.45431 |
| TREM1 | triggering receptor expressed on myeloid cells 1 | 3.36766 |
| SLC35A3 | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 | 2.99011 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 2.88071 |
| DENND2D | DENN/MADD domain containing 2D | 2.86988 |
| TNIP1 | TNFAIP3 interacting protein 1 | 2.84845 |
| SLC3A2 | solute carrier family 3 (amino acid transporter heavy chain), member 2 | 2.67313 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 2.52439 |
| EPHA3 | EPH receptor A3 | 2.43472 |
| LPAR2 | lysophosphatidic acid receptor 2 | 2.43326 |
| JADE2 | jade family PHD finger 2 | 2.38684 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 2.36473 |
| SLC25A32 | solute carrier family 25 (mitochondrial folate carrier), member 32 | 2.33125 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 2.3242 |
| CHN1 | chimerin 1 | 2.29661 |
| PTPN7 | protein tyrosine phosphatase, non-receptor type 7 | 2.26734 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | 2.19672 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 2.15626 |
| DDX10 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 | 2.14046 |
| RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 | 2.08629 |
| PAX9 | paired box 9 | 2.07519 |
| TXNL4B | thioredoxin-like 4B | 2.07195 |
| SAP130 | Sin3A-associated protein, 130kDa | 2.06294 |
| FOXE1 | forkhead box E1 | 2.0629 |
| CD180 | CD180 molecule | 2.02212 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ZDHHC6 | zinc finger, DHHC-type containing 6 | -9.42214 |
| GNAS | GNAS complex locus | -6.65275 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -6.07329 |
| PCNA | proliferating cell nuclear antigen | -5.5748 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -5.38281 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -5.09209 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -5.05909 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -4.79094 |
| HMG20B | high mobility group 20B | -4.772 |
| THAP11 | THAP domain containing 11 | -4.65537 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -4.37978 |
| SLC35F2 | solute carrier family 35, member F2 | -4.2685 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -4.10269 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -3.94269 |
| SCCPDH | saccharopine dehydrogenase (putative) | -3.63126 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -3.61478 |
| FGFR4 | fibroblast growth factor receptor 4 | -3.14748 |
| PROS1 | protein S (alpha) | -3.06766 |
| TM9SF2 | transmembrane 9 superfamily member 2 | -2.84522 |
| TCTN1 | tectonic family member 1 | -2.81193 |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) | -2.79779 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.58745 |
| RFC2 | replication factor C (activator 1) 2, 40kDa | -2.44581 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | -2.3808 |
| MPV17L-BMERB1 | MPV17L-BMERB1 readthrough | -2.343 |
| RPP30 | ribonuclease P/MRP 30kDa subunit | -2.33019 |
| SPAG4 | sperm associated antigen 4 | -2.31777 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -2.28551 |
| MORF4L2 | mortality factor 4 like 2 | -2.27121 |
| SYNGR3 | synaptogyrin 3 | -2.26084 |
| ADI1 | acireductone dioxygenase 1 | -2.25516 |
| MPC1 | mitochondrial pyruvate carrier 1 | -2.15111 |
| CAB39 | calcium binding protein 39 | -2.11654 |
| TCEAL4 | transcription elongation factor A (SII)-like 4 | -2.11406 |
| FBXL12 | F-box and leucine-rich repeat protein 12 | -2.08019 |
| ACTR10 | actin-related protein 10 homolog (S. cerevisiae) | -2.04809 |
| USP2 | ubiquitin specific peptidase 2 | -2.03728 |
