| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 1,2-dichlorobenzene 2.52 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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55 genes differentially expressed following the CRCGN010_HEPG2_24H:K05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 7.71478 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 6.62696 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 6.40586 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 4.85634 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 4.31622 |
| E2F2 | E2F transcription factor 2 | 4.305 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 3.92149 |
| CYCS | cytochrome c, somatic | 3.74386 |
| MAP7 | microtubule-associated protein 7 | 3.64073 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 3.63442 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | 3.59927 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | 3.01143 |
| HEBP1 | heme binding protein 1 | 2.91752 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 2.89148 |
| RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 | 2.81362 |
| FZD7 | frizzled class receptor 7 | 2.75374 |
| SNX7 | sorting nexin 7 | 2.73956 |
| LPAR2 | lysophosphatidic acid receptor 2 | 2.71111 |
| AMDHD2 | amidohydrolase domain containing 2 | 2.66854 |
| CEP57 | centrosomal protein 57kDa | 2.62185 |
| TREM1 | triggering receptor expressed on myeloid cells 1 | 2.52947 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 2.50688 |
| BTK | Bruton agammaglobulinemia tyrosine kinase | 2.34154 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | 2.25613 |
| GPATCH8 | G patch domain containing 8 | 2.22621 |
| NOSIP | nitric oxide synthase interacting protein | 2.14857 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 2.13999 |
| CHN1 | chimerin 1 | 2.10324 |
| PRR15L | proline rich 15-like | 2.04523 |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 | 2.03344 |
| PIH1D1 | PIH1 domain containing 1 | 2.03264 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CCNB2 | cyclin B2 | -6.94184 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -4.59882 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | -4.51027 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -4.48974 |
| LAP3 | leucine aminopeptidase 3 | -4.3544 |
| TLR4 | toll-like receptor 4 | -4.34998 |
| KDM3A | lysine (K)-specific demethylase 3A | -4.229 |
| PLK1 | polo-like kinase 1 | -4.16298 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -3.75982 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -3.33939 |
| CCNB1 | cyclin B1 | -3.15141 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -3.00562 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -2.81381 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -2.71656 |
| TLCD3A | TLC domain containing 3A | -2.62162 |
| SPAG4 | sperm associated antigen 4 | -2.61404 |
| SNX11 | sorting nexin 11 | -2.54623 |
| GTPBP8 | GTP-binding protein 8 (putative) | -2.47581 |
| WASHC4 | WASH complex subunit 4 | -2.41041 |
| CDC20 | cell division cycle 20 | -2.25832 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -2.17502 |
| VAT1 | vesicle amine transport 1 | -2.15187 |
| ADI1 | acireductone dioxygenase 1 | -2.08847 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -2.05032 |
