CRCGN010_HEPG2_24H:K11 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description vorinostat 1.25 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

502 genes differentially expressed following the CRCGN010_HEPG2_24H:K11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
UBE2L6 ubiquitin-conjugating enzyme E2L 6 10.0
FOXO4 forkhead box O4 10.0
CBR1 carbonyl reductase 1 9.65385
DNM1 dynamin 1 8.13737
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 7.67912
PLA2G15 phospholipase A2, group XV 7.31922
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 6.85922
ALDOC aldolase C, fructose-bisphosphate 6.75406
UBQLN2 ubiquilin 2 6.74456
MYC v-myc avian myelocytomatosis viral oncogene homolog 6.49941
TCEA2 transcription elongation factor A (SII), 2 6.39918
HMG20B high mobility group 20B 6.34925
CDPF1 cysteine-rich, DPF motif domain containing 1 6.16087
LGMN legumain 6.13515
H2BC12 H2B clustered histone 12 6.03948
MAP7 microtubule-associated protein 7 5.97405
PPARG peroxisome proliferator-activated receptor gamma 5.85975
CARMIL1 capping protein regulator and myosin 1 linker 1 5.60613
SKIC2 SKI2 subunit of superkiller complex 5.53951
MVP major vault protein 5.52372
STX1A syntaxin 1A (brain) 5.3783
TIMP2 TIMP metallopeptidase inhibitor 2 5.13451
ABHD6 abhydrolase domain containing 6 5.09575
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta 5.00593
ABHD4 abhydrolase domain containing 4 4.96166
DUSP6 dual specificity phosphatase 6 4.89663
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide 4.89289
PRR15L proline rich 15-like 4.81036
NUCB2 nucleobindin 2 4.78277
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 4.76395
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 4.31873
ANO10 anoctamin 10 4.16075
PRKCD protein kinase C, delta 4.13847
EGR1 early growth response 1 4.06989
USP6NL USP6 N-terminal like 4.01014
HMOX1 heme oxygenase 1 3.9571
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 3.94388
FCHO1 FCH domain only 1 3.89623
GFOD1 glucose-fructose oxidoreductase domain containing 1 3.87668
ZMIZ1 zinc finger, MIZ-type containing 1 3.69449
AARS1 alanyl-tRNA synthetase 1 3.65256
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 3.65084
STK10 serine/threonine kinase 10 3.64631
TMEM50A transmembrane protein 50A 3.57471
CCL2 chemokine (C-C motif) ligand 2 3.56977
INTS3 integrator complex subunit 3 3.5646
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like 3.52709
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 3.51192
TBPL1 TBP-like 1 3.48261
HSPA1A heat shock 70kDa protein 1A 3.47072
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 3.41092
CXCL2 chemokine (C-X-C motif) ligand 2 3.37109
PTPN12 protein tyrosine phosphatase, non-receptor type 12 3.34169
LCN2 lipocalin 2 3.31275
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 3.3047
DIPK1A divergent protein kinase domain 1A 3.28156
BAMBI BMP and activin membrane-bound inhibitor 3.27611
NIT1 nitrilase 1 3.23966
TXNRD1 thioredoxin reductase 1 3.23228
ADAM10 ADAM metallopeptidase domain 10 3.2089
STXBP1 syntaxin binding protein 1 3.17222
CTSL cathepsin L 3.15801
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 3.14296
EPN2 epsin 2 3.14161
STXBP2 syntaxin binding protein 2 3.14045
TAC4 tachykinin 4 (hemokinin) 3.13338
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 3.10462
H2AC6 H2A clustered histone 6 3.08171
FAT1 FAT atypical cadherin 1 3.0698
CGRRF1 cell growth regulator with ring finger domain 1 3.064
CCND3 cyclin D3 3.05893
DDB2 damage-specific DNA binding protein 2, 48kDa 3.04299
CCDC71 coiled-coil domain containing 71 3.03641
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae) 3.02956
CDR2L cerebellar degeneration-related protein 2-like 3.01317
TRIB1 tribbles pseudokinase 1 2.99829
THSD7A thrombospondin, type I, domain containing 7A 2.9966
GATA3 GATA binding protein 3 2.95536
CRABP2 cellular retinoic acid binding protein 2 2.94915
GPR162 G protein-coupled receptor 162 2.94436
GJA4 gap junction protein, alpha 4, 37kDa 2.93438
FPGS folylpolyglutamate synthase 2.92748
ATP11B ATPase, class VI, type 11B 2.91392
CALM3 calmodulin 3 (phosphorylase kinase, delta) 2.91391
FRMD4B FERM domain containing 4B 2.8899
TWF2 twinfilin actin binding protein 2 2.88438
IGFBP3 insulin-like growth factor binding protein 3 2.87173
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha) 2.85636
BACE2 beta-site APP-cleaving enzyme 2 2.83978
VAT1 vesicle amine transport 1 2.81755
BBC3 BCL2 binding component 3 2.80566
TBC1D15 TBC1 domain family, member 15 2.77077
DENND2D DENN/MADD domain containing 2D 2.76392
AMPD2 adenosine monophosphate deaminase 2 2.70667
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit 2.69511
GSTZ1 glutathione S-transferase zeta 1 2.68797
IER3 immediate early response 3 2.68772
DYNLT3 dynein, light chain, Tctex-type 3 2.6758
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 2.67456
CNPY4 canopy FGF signaling regulator 4 2.67386
GATA2 GATA binding protein 2 2.66897
LSR lipolysis stimulated lipoprotein receptor 2.66041
RAB3A RAB3A, member RAS oncogene family 2.61192
IQCC IQ motif containing C 2.61155
NPDC1 neural proliferation, differentiation and control, 1 2.61154
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) 2.60883
ZDHHC6 zinc finger, DHHC-type containing 6 2.59856
INPP1 inositol polyphosphate-1-phosphatase 2.57746
CYCS cytochrome c, somatic 2.55417
CELF3 CUGBP, Elav-like family member 3 2.53551
CCP110 centriolar coiled coil protein 110kDa 2.5348
ARFIP2 ADP-ribosylation factor interacting protein 2 2.5314
ELAVL3 ELAV like neuron-specific RNA binding protein 3 2.52201
IKZF1 IKAROS family zinc finger 1 (Ikaros) 2.5183
DACH1 dachshund family transcription factor 1 2.50343
PPARD peroxisome proliferator-activated receptor delta 2.48808
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) 2.48723
S100A11 S100 calcium binding protein A11 2.48694
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) 2.48598
USB1 U6 snRNA biogenesis 1 2.48093
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II 2.47229
CYB561 cytochrome b561 2.46354
COG7 component of oligomeric golgi complex 7 2.45717
FABP2 fatty acid binding protein 2, intestinal 2.42447
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B 2.42322
GRN granulin 2.41836
MYCT1 myc target 1 2.40992
LIG4 ligase IV, DNA, ATP-dependent 2.40258
ZNF646 zinc finger protein 646 2.38911
GNB5 guanine nucleotide binding protein (G protein), beta 5 2.3879
UNC93B1 unc-93 homolog B1 (C. elegans) 2.3842
PROCR protein C receptor, endothelial 2.37617
IGF1R insulin-like growth factor 1 receptor 2.36641
KIAA0319 KIAA0319 2.36289
SH3BP5 SH3-domain binding protein 5 (BTK-associated) 2.35871
RSU1 Ras suppressor protein 1 2.35851
KLHDC2 kelch domain containing 2 2.35835
BMP4 bone morphogenetic protein 4 2.35657
VGLL4 vestigial-like family member 4 2.3538
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 2.35337
RTN2 reticulon 2 2.35282
DHRS7 dehydrogenase/reductase (SDR family) member 7 2.34594
TPPP tubulin polymerization promoting protein 2.34593
KLHL24 kelch-like family member 24 2.34315
EID1 EP300 interacting inhibitor of differentiation 1 2.3431
MAPK3 mitogen-activated protein kinase 3 2.34135
HLA-E major histocompatibility complex, class I, E 2.33034
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1 2.32223
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 2.31585
MMRN2 multimerin 2 2.30925
LGALS1 lectin, galactoside-binding, soluble, 1 2.30759
PRCP prolylcarboxypeptidase (angiotensinase C) 2.28733
FBXO2 F-box protein 2 2.28671
VPS37B vacuolar protein sorting 37 homolog B (S. cerevisiae) 2.28438
SNX7 sorting nexin 7 2.27983
PTPN1 protein tyrosine phosphatase, non-receptor type 1 2.27954
ADGRL4 adhesion G protein-coupled receptor L4 2.26846
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 2.26738
TERF2IP telomeric repeat binding factor 2, interacting protein 2.25793
COL1A1 collagen, type I, alpha 1 2.25126
ADGRG1 adhesion G protein-coupled receptor G1 2.25078
OCEL1 occludin/ELL domain containing 1 2.24741
KIF5C kinesin family member 5C 2.24739
HABP4 hyaluronan binding protein 4 2.24576
CYTH1 cytohesin 1 2.23765
NCOA3 nuclear receptor coactivator 3 2.22759
SFXN3 sideroflexin 3 2.22755
GPATCH8 G patch domain containing 8 2.22003
DNM3 dynamin 3 2.20867
TM4SF20 transmembrane 4 L six family member 20 2.20865
AKR1C3 aldo-keto reductase family 1, member C3 2.20266
RYBP RING1 and YY1 binding protein 2.19479
CYP2A13 cytochrome P450, family 2, subfamily A, polypeptide 13 2.19379
APH1B APH1B gamma secretase subunit 2.19027
OSR2 odd-skipped related transciption factor 2 2.18985
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase 2.1842
HDAC7 histone deacetylase 7 2.18289
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble 2.18184
SYNGAP1 synaptic Ras GTPase activating protein 1 2.17914
NME7 NME/NM23 family member 7 2.17888
IGF2R insulin-like growth factor 2 receptor 2.17363
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 2.17326
RPA3 replication protein A3, 14kDa 2.16606
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 2.1572
PHF1 PHD finger protein 1 2.1549
TM9SF2 transmembrane 9 superfamily member 2 2.15342
CAMLG calcium modulating ligand 2.15216
ADAP2 ArfGAP with dual PH domains 2 2.14902
TARS2 threonyl-tRNA synthetase 2, mitochondrial (putative) 2.14742
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12 2.14591
MCOLN1 mucolipin 1 2.14536
ACP5 acid phosphatase 5, tartrate resistant 2.14486
ADAR adenosine deaminase, RNA-specific 2.13729
CXCL5 chemokine (C-X-C motif) ligand 5 2.13647
BCKDK branched chain ketoacid dehydrogenase kinase 2.12843
FAM110D family with sequence similarity 110, member D 2.12493
HDGFL3 HDGF like 3 2.12383
MAGEH1 melanoma antigen family H1 2.11652
TRAPPC6A trafficking protein particle complex 6A 2.11641
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor 2.11595
ZBTB22 zinc finger and BTB domain containing 22 2.11476
PAIP2B poly(A) binding protein interacting protein 2B 2.09773
SCAMP5 secretory carrier membrane protein 5 2.09673
SSH3 slingshot protein phosphatase 3 2.09499
VAMP4 vesicle-associated membrane protein 4 2.09295
CLDN6 claudin 6 2.08587
CSNK1E casein kinase 1, epsilon 2.08193
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 2.07231
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 2.07211
RNF13 ring finger protein 13 2.06992
TMSB10 thymosin beta 10 2.0698
MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2 2.06624
EFNA3 ephrin-A3 2.04721
ERCC5 excision repair cross-complementation group 5 2.04365
DHX40 DEAH (Asp-Glu-Ala-His) box polypeptide 40 2.0414
TUBB6 tubulin, beta 6 class V 2.0398
H1-2 H1.2 linker histone, cluster member 2.03442
PCM1 pericentriolar material 1 2.03314
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 2.02379
CDH5 cadherin 5, type 2 (vascular endothelium) 2.0232
MMP2 matrix metallopeptidase 2 2.02094
NALF1 NALCN channel auxiliary factor 1 2.01762
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) 2.01277
GRIA2 glutamate receptor, ionotropic, AMPA 2 2.01239
AMDHD2 amidohydrolase domain containing 2 2.01002
TDRD7 tudor domain containing 7 2.00836
MUC13 mucin 13, cell surface associated 2.00827
MNAT1 MNAT CDK-activating kinase assembly factor 1 2.00028

decreased expression

Symbol Name Standardized Value
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -9.30551
TCERG1 transcription elongation regulator 1 -8.21828
PGM1 phosphoglucomutase 1 -7.87366
CD320 CD320 molecule -7.85314
PLEKHJ1 pleckstrin homology domain containing, family J member 1 -7.70021
ADI1 acireductone dioxygenase 1 -7.66187
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -7.02038
RPIA ribose 5-phosphate isomerase A -6.96848
STAMBP STAM binding protein -6.7738
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -6.5885
CCNA2 cyclin A2 -6.21214
KEAP1 kelch-like ECH-associated protein 1 -6.15649
TCTN1 tectonic family member 1 -5.95782
TLCD3A TLC domain containing 3A -5.92982
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -5.92295
MELK maternal embryonic leucine zipper kinase -5.85532
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -5.56137
LOC124907782 dual specificity protein phosphatase 22 -5.55249
UBE2C ubiquitin-conjugating enzyme E2C -5.50627
FOSL1 FOS-like antigen 1 -5.49787
FAIM Fas apoptotic inhibitory molecule -5.49328
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -5.39745
CDK1 cyclin-dependent kinase 1 -5.33776
TATDN2 TatD DNase domain containing 2 -5.22174
CRELD2 cysteine-rich with EGF-like domains 2 -5.19518
GTPBP8 GTP-binding protein 8 (putative) -5.07948
RRAGA Ras-related GTP binding A -5.00334
NUP85 nucleoporin 85kDa -4.99533
STAP2 signal transducing adaptor family member 2 -4.97144
SPAG7 sperm associated antigen 7 -4.96279
NNT nicotinamide nucleotide transhydrogenase -4.88195
SACM1L SAC1 suppressor of actin mutations 1-like (yeast) -4.86653
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha -4.84309
CHEK1 checkpoint kinase 1 -4.8235
SOAT2 sterol O-acyltransferase 2 -4.81574
MRPS2 mitochondrial ribosomal protein S2 -4.79121
ISOC1 isochorismatase domain containing 1 -4.78966
PLK1 polo-like kinase 1 -4.76132
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 -4.75048
TRIB3 tribbles pseudokinase 3 -4.73761
SCCPDH saccharopine dehydrogenase (putative) -4.71962
DERA deoxyribose-phosphate aldolase (putative) -4.69132
CCNB2 cyclin B2 -4.65422
BDH1 3-hydroxybutyrate dehydrogenase, type 1 -4.55155
ECH1 enoyl CoA hydratase 1, peroxisomal -4.53968
NGRN neugrin, neurite outgrowth associated -4.51614
MRPS16 mitochondrial ribosomal protein S16 -4.45166
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha -4.43897
TMEM109 transmembrane protein 109 -4.23789
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -4.22199
LRRC41 leucine rich repeat containing 41 -4.18676
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -4.04666
CDK4 cyclin-dependent kinase 4 -4.00546
ZW10 zw10 kinetochore protein -3.87468
NUP62 nucleoporin 62kDa -3.87287
RFC2 replication factor C (activator 1) 2, 40kDa -3.86928
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -3.86357
CDC25A cell division cycle 25A -3.83758
MSRA methionine sulfoxide reductase A -3.80974
SLC35B1 solute carrier family 35, member B1 -3.73604
RCC1L RCC1 like -3.66835
PROS1 protein S (alpha) -3.6467
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked -3.59544
CASC3 cancer susceptibility candidate 3 -3.59274
SLC35F2 solute carrier family 35, member F2 -3.58015
FOXM1 forkhead box M1 -3.56904
ICAM3 intercellular adhesion molecule 3 -3.54102
RPS4Y1 ribosomal protein S4, Y-linked 1 -3.53064
TM9SF3 transmembrane 9 superfamily member 3 -3.50899
TOR1A torsin family 1, member A (torsin A) -3.42649
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 -3.38351
YKT6 YKT6 v-SNARE homolog (S. cerevisiae) -3.37959
PUF60 poly-U binding splicing factor 60KDa -3.37466
KIF11 kinesin family member 11 -3.3132
HADH hydroxyacyl-CoA dehydrogenase -3.26553
POLA2 polymerase (DNA directed), alpha 2, accessory subunit -3.26205
NUP88 nucleoporin 88kDa -3.22955
KIF14 kinesin family member 14 -3.21826
EXO1 exonuclease 1 -3.19154
FBXO7 F-box protein 7 -3.18481
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B -3.17694
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) -3.16696
PCCB propionyl CoA carboxylase, beta polypeptide -3.15303
FANCG Fanconi anemia, complementation group G -3.1351
CASP7 caspase 7, apoptosis-related cysteine peptidase -3.12715
CHAF1B chromatin assembly factor 1, subunit B (p60) -3.12106
DCTD dCMP deaminase -3.1128
BIRC5 baculoviral IAP repeat containing 5 -3.10512
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3 -3.09633
LDHD lactate dehydrogenase D -3.0577
RBM15B RNA binding motif protein 15B -3.05156
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) -3.0418
CDC6 cell division cycle 6 -3.00241
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa -2.9302
CPNE3 copine III -2.90493
TPM1 tropomyosin 1 (alpha) -2.90085
ACAA1 acetyl-CoA acyltransferase 1 -2.88237
TSEN2 TSEN2 tRNA splicing endonuclease subunit -2.87792
IDE insulin-degrading enzyme -2.87724
SMC4 structural maintenance of chromosomes 4 -2.87523
AURKA aurora kinase A -2.86972
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -2.86783
RFC3 replication factor C (activator 1) 3, 38kDa -2.85735
POLD1 polymerase (DNA directed), delta 1, catalytic subunit -2.84334
RXYLT1 ribitol xylosyltransferase 1 -2.83989
PCNT pericentrin -2.83157
TSPAN6 tetraspanin 6 -2.81942
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase -2.81372
TMEM97 transmembrane protein 97 -2.80999
CCNB1 cyclin B1 -2.77763
NEIL3 nei endonuclease VIII-like 3 (E. coli) -2.74746
RWDD2B RWD domain containing 2B -2.74482
ACOT2 acyl-CoA thioesterase 2 -2.73791
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial) -2.73318
DNM1L dynamin 1-like -2.72133
ZBTB35 zinc finger and BTB domain containing 35 -2.72003
TROAP trophinin associated protein -2.71845
KRCC1 lysine-rich coiled-coil 1 -2.71801
DCK deoxycytidine kinase -2.69727
MDN1 MDN1, midasin homolog (yeast) -2.69089
GYS1 glycogen synthase 1 (muscle) -2.68117
ATF5 activating transcription factor 5 -2.68102
CDT1 chromatin licensing and DNA replication factor 1 -2.67852
TIMELESS timeless circadian clock -2.67168
IGHMBP2 immunoglobulin mu binding protein 2 -2.66079
OXCT1 3-oxoacid CoA transferase 1 -2.65975
TTK TTK protein kinase -2.65749
STIL SCL/TAL1 interrupting locus -2.6535
MCRS1 microspherule protein 1 -2.63021
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 -2.62673
CHAF1A chromatin assembly factor 1, subunit A (p150) -2.59837
THOC1 THO complex 1 -2.5925
MLYCD malonyl-CoA decarboxylase -2.58734
FBXO5 F-box protein 5 -2.57974
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -2.57329
ELAC2 elaC ribonuclease Z 2 -2.56561
CDCA8 cell division cycle associated 8 -2.5653
HLA-DOB major histocompatibility complex, class II, DO beta -2.55671
KLHL21 kelch-like family member 21 -2.55243
CEP55 centrosomal protein 55kDa -2.54431
CHURC1-FNTB CHURC1-FNTB readthrough -2.53704
PHF2 PHD finger protein 2 -2.53693
NCAPD3 non-SMC condensin II complex, subunit D3 -2.52521
ZBED1 zinc finger, BED-type containing 1 -2.51812
DPP3 dipeptidyl-peptidase 3 -2.5144
TFDP1 transcription factor Dp-1 -2.51059
MCM10 minichromosome maintenance complex component 10 -2.51033
SNRNP25 small nuclear ribonucleoprotein 25kDa (U11/U12) -2.50057
NCAPH non-SMC condensin I complex, subunit H -2.49907
ANAPC1 anaphase promoting complex subunit 1 -2.49693
MRPL19 mitochondrial ribosomal protein L19 -2.49571
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta -2.49274
ZNF586 zinc finger protein 586 -2.48554
ATXN10 ataxin 10 -2.47026
ITGB5 integrin, beta 5 -2.46568
EIF5 eukaryotic translation initiation factor 5 -2.46109
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -2.45947
SPAG4 sperm associated antigen 4 -2.45052
HMGA2 high mobility group AT-hook 2 -2.44997
TOPBP1 topoisomerase (DNA) II binding protein 1 -2.44572
LOC100652777 group 10 secretory phospholipase A2-like -2.43009
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor -2.42971
NDC80 NDC80 kinetochore complex component -2.42379
ASF1B anti-silencing function 1B histone chaperone -2.4227
RFC5 replication factor C (activator 1) 5, 36.5kDa -2.42087
GINS3 GINS complex subunit 3 (Psf3 homolog) -2.41712
GPR27 G protein-coupled receptor 27 -2.4093
SPDL1 spindle apparatus coiled-coil protein 1 -2.40512
ATP9B ATPase, class II, type 9B -2.40161
BARD1 BRCA1 associated RING domain 1 -2.39675
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble -2.38147
TERT telomerase reverse transcriptase -2.37667
TSSC4 tumor suppressing subtransferable candidate 4 -2.37195
MTA1 metastasis associated 1 -2.37174
GTSE1 G-2 and S-phase expressed 1 -2.37137
GINS2 GINS complex subunit 2 (Psf2 homolog) -2.37117
PLK4 polo-like kinase 4 -2.36637
DBF4 DBF4 zinc finger -2.35936
ZNF282 zinc finger protein 282 -2.35702
NSD2 nuclear receptor binding SET domain protein 2 -2.35154
KCTD15 potassium channel tetramerization domain containing 15 -2.32403
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 -2.31671
VBP1 von Hippel-Lindau binding protein 1 -2.31469
MTMR2 myotubularin related protein 2 -2.31257
CAPN15 calpain 15 -2.30839
POLR1A polymerase (RNA) I polypeptide A, 194kDa -2.30192
TUBGCP5 tubulin, gamma complex associated protein 5 -2.30033
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B -2.29443
KIF18B kinesin family member 18B -2.29053
POLR3K polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa -2.2847
GNAS GNAS complex locus -2.27833
TIMCC TIM double twin CX3C motif chaperone -2.27687
DENND4B DENN/MADD domain containing 4B -2.27658
HJURP Holliday junction recognition protein -2.26895
KIF15 kinesin family member 15 -2.26423
NUBP2 nucleotide binding protein 2 -2.26123
POLE polymerase (DNA directed), epsilon, catalytic subunit -2.2569
PROSER1 proline and serine rich 1 -2.2479
MOK MOK protein kinase -2.24551
SUMF2 sulfatase modifying factor 2 -2.23987
NT5DC2 5'-nucleotidase domain containing 2 -2.23122
RNASE7 ribonuclease, RNase A family, 7 -2.22912
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -2.22884
CYREN cell cycle regulator of NHEJ -2.22698
RAD54L RAD54-like (S. cerevisiae) -2.22621
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit -2.22221
ERCC6L excision repair cross-complementation group 6-like -2.22138
HYOU1 hypoxia up-regulated 1 -2.22038
USP39 ubiquitin specific peptidase 39 -2.20629
PARP1 poly (ADP-ribose) polymerase 1 -2.19722
AKT1 v-akt murine thymoma viral oncogene homolog 1 -2.19477
LANCL2 LanC lantibiotic synthetase component C-like 2 (bacterial) -2.1911
SKA1 spindle and kinetochore associated complex subunit 1 -2.19029
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila) -2.1884
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -2.18436
HMMR hyaluronan-mediated motility receptor (RHAMM) -2.18071
PIEZO1 piezo-type mechanosensitive ion channel component 1 -2.17897
KCNK2 potassium channel, two pore domain subfamily K, member 2 -2.17769
SHCBP1 SHC SH2-domain binding protein 1 -2.17574
COL2A1 collagen, type II, alpha 1 -2.173
FAM174C family with sequence similarity 174 member C -2.17104
TARBP2 TAR (HIV-1) RNA binding protein 2 -2.16969
HDDC2 HD domain containing 2 -2.16707
RBM14-RBM4 RBM14-RBM4 readthrough -2.16422
DHFR dihydrofolate reductase -2.15512
POLDIP2 polymerase (DNA-directed), delta interacting protein 2 -2.15396
MYL3 myosin, light chain 3, alkali; ventricular, skeletal, slow -2.14887
NCK2 NCK adaptor protein 2 -2.14756
E2F8 E2F transcription factor 8 -2.14627
MRPL39 mitochondrial ribosomal protein L39 -2.13884
GNPDA1 glucosamine-6-phosphate deaminase 1 -2.13448
KIF4A kinesin family member 4A -2.13371
CHST10 carbohydrate sulfotransferase 10 -2.1337
NCAPG2 non-SMC condensin II complex, subunit G2 -2.13134
HAT1 histone acetyltransferase 1 -2.12773
PHKA1 phosphorylase kinase, alpha 1 (muscle) -2.12712
ANKRD44 ankyrin repeat domain 44 -2.12408
ENOSF1 enolase superfamily member 1 -2.12364
SEH1L SEH1-like (S. cerevisiae) -2.11469
POLK polymerase (DNA directed) kappa -2.11422
ZC3H14 zinc finger CCCH-type containing 14 -2.11061
BLM Bloom syndrome, RecQ helicase-like -2.1079
MLST8 MTOR associated protein, LST8 homolog (S. cerevisiae) -2.10644
CAPN3 calpain 3, (p94) -2.09887
EPB41L2 erythrocyte membrane protein band 4.1-like 2 -2.09066
RFWD3 ring finger and WD repeat domain 3 -2.08656
NIBAN1 niban apoptosis regulator 1 -2.08596
FASN fatty acid synthase -2.07725
BCL7B B-cell CLL/lymphoma 7B -2.07621
CENPA centromere protein A -2.07577
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -2.07502
POLR1G RNA polymerase I subunit G -2.07395
DSCC1 DNA replication and sister chromatid cohesion 1 -2.07361
VCP valosin containing protein -2.07121
SLC25A38 solute carrier family 25, member 38 -2.06791
USP22 ubiquitin specific peptidase 22 -2.06765
TYK2 tyrosine kinase 2 -2.06501
THOP1 thimet oligopeptidase 1 -2.06139
TRPV4 transient receptor potential cation channel, subfamily V, member 4 -2.06024
AUNIP aurora kinase A and ninein interacting protein -2.05649
BORA bora, aurora kinase A activator -2.05226
ASCC3 activating signal cointegrator 1 complex subunit 3 -2.04973
DEPDC1 DEP domain containing 1 -2.04723
TARBP1 TAR (HIV-1) RNA binding protein 1 -2.04215
HACD1 3-hydroxyacyl-CoA dehydratase 1 -2.03894
GTPBP6 GTP binding protein 6 (putative) -2.03824
GINS1 GINS complex subunit 1 (Psf1 homolog) -2.03492
MTHFSD methenyltetrahydrofolate synthetase domain containing -2.03213
TDP1 tyrosyl-DNA phosphodiesterase 1 -2.02198
NEMP1 nuclear envelope integral membrane protein 1 -2.01877
PPIE peptidylprolyl isomerase E (cyclophilin E) -2.01309
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -2.01289
FEN1 flap structure-specific endonuclease 1 -2.01083
SPC25 SPC25, NDC80 kinetochore complex component -2.00958