CRCGN010_HEPG2_24H:K15 Gene Set
Genes
57 genes differentially expressed following the CRCGN010_HEPG2_24H:K15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
AMDHD2
|
amidohydrolase domain containing 2
|
8.18961
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
4.66502
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
4.64664
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
4.45267
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
4.26785
|
|
BPHL
|
biphenyl hydrolase-like (serine hydrolase)
|
3.9879
|
|
PRR15L
|
proline rich 15-like
|
3.98456
|
|
STIMATE
|
STIM activating enhancer
|
3.93049
|
|
CRELD2
|
cysteine-rich with EGF-like domains 2
|
3.92974
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
3.73958
|
|
PLSCR3
|
phospholipid scramblase 3
|
3.62939
|
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
3.28471
|
|
CCNE2
|
cyclin E2
|
3.20029
|
|
TBXA2R
|
thromboxane A2 receptor
|
2.58267
|
|
BIRC2
|
baculoviral IAP repeat containing 2
|
2.57587
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.55642
|
|
LCN2
|
lipocalin 2
|
2.54621
|
|
CHN1
|
chimerin 1
|
2.52373
|
|
CBR3
|
carbonyl reductase 3
|
2.47948
|
|
MAP3K4
|
mitogen-activated protein kinase kinase kinase 4
|
2.39314
|
|
KAT6A
|
K(lysine) acetyltransferase 6A
|
2.36496
|
|
MAP7
|
microtubule-associated protein 7
|
2.34384
|
|
DCUN1D4
|
DCN1, defective in cullin neddylation 1, domain containing 4
|
2.27898
|
|
IPO13
|
importin 13
|
2.14617
|
|
EPHA3
|
EPH receptor A3
|
2.14079
|
|
HOXD10
|
homeobox D10
|
2.05767
|
|
TGFBR1
|
transforming growth factor, beta receptor 1
|
2.01225
|
|
TIMM22
|
translocase of inner mitochondrial membrane 22 homolog (yeast)
|
2.00618
|
|
SMIM40
|
small integral membrane protein 40
|
2.00585
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
TLR4
|
toll-like receptor 4
|
-7.10047
|
|
ZNF586
|
zinc finger protein 586
|
-7.04069
|
|
CCNB2
|
cyclin B2
|
-5.91984
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-5.1064
|
|
TLCD3A
|
TLC domain containing 3A
|
-4.49051
|
|
TRIB3
|
tribbles pseudokinase 3
|
-4.40289
|
|
CCDC86
|
coiled-coil domain containing 86
|
-4.31125
|
|
ZDHHC6
|
zinc finger, DHHC-type containing 6
|
-4.14673
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-4.07972
|
|
LDHD
|
lactate dehydrogenase D
|
-3.59134
|
|
TNFRSF21
|
tumor necrosis factor receptor superfamily, member 21
|
-3.49802
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-3.29141
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.2742
|
|
HAT1
|
histone acetyltransferase 1
|
-3.14832
|
|
PPP2R3C
|
protein phosphatase 2, regulatory subunit B'', gamma
|
-3.11262
|
|
VDAC1
|
voltage-dependent anion channel 1
|
-3.00709
|
|
G3BP1
|
GTPase activating protein (SH3 domain) binding protein 1
|
-2.88352
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-2.83477
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.82618
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.61219
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
-2.5373
|
|
WASHC4
|
WASH complex subunit 4
|
-2.3799
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-2.37797
|
|
RNF167
|
ring finger protein 167
|
-2.33445
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.21746
|
|
ZNF587B
|
zinc finger protein 587B
|
-2.1157
|
|
ITGB1BP1
|
integrin beta 1 binding protein 1
|
-2.04974
|
|
DDX3Y
|
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
|
-2.03685
|
