| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | lithocholic-acid 4.98 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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80 genes differentially expressed following the CRCGN010_HEPG2_24H:K16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LCN2 | lipocalin 2 | 10.0 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 5.91798 |
| CHN1 | chimerin 1 | 5.90132 |
| MAP7 | microtubule-associated protein 7 | 5.74542 |
| AMDHD2 | amidohydrolase domain containing 2 | 5.73301 |
| RPL39L | ribosomal protein L39-like | 5.3104 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 5.08643 |
| JADE2 | jade family PHD finger 2 | 5.08355 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 5.01775 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 4.60179 |
| GPER1 | G protein-coupled estrogen receptor 1 | 4.38086 |
| MAMLD1 | mastermind-like domain containing 1 | 4.29357 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit | 4.23337 |
| INTS3 | integrator complex subunit 3 | 4.16494 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 3.84971 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 3.72449 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 3.65885 |
| E2F2 | E2F transcription factor 2 | 3.64586 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 3.38682 |
| KIF5C | kinesin family member 5C | 3.03239 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | 3.01615 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 2.96608 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | 2.66294 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 2.57533 |
| EPN2 | epsin 2 | 2.55733 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 2.52452 |
| ADORA3 | adenosine A3 receptor | 2.43731 |
| CLDN10 | claudin 10 | 2.43282 |
| TTC12 | tetratricopeptide repeat domain 12 | 2.42 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 2.37866 |
| APOO | apolipoprotein O | 2.25356 |
| PDCD6 | programmed cell death 6 | 2.25317 |
| FRK | fyn-related Src family tyrosine kinase | 2.25103 |
| SNAP91 | synaptosomal-associated protein, 91kDa | 2.24598 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 2.24469 |
| BIRC2 | baculoviral IAP repeat containing 2 | 2.24028 |
| DIPK1A | divergent protein kinase domain 1A | 2.23223 |
| MCUR1 | mitochondrial calcium uniporter regulator 1 | 2.18995 |
| CD82 | CD82 molecule | 2.10262 |
| ATP8B4 | ATPase, class I, type 8B, member 4 | 2.06254 |
| CSTPP1 | centriolar satellite-associated tubulin polyglutamylase complex regulator 1 | 2.04821 |
| C2CD2 | C2 calcium-dependent domain containing 2 | 2.02226 |
| GPC5 | glypican 5 | 2.01909 |
| OCA2 | oculocutaneous albinism II | 2.01233 |
| SPATA6 | spermatogenesis associated 6 | 2.00829 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -5.55647 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -4.71562 |
| IDH1 | isocitrate dehydrogenase 1 (NADP+), soluble | -4.43637 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -4.26692 |
| CDC20 | cell division cycle 20 | -4.09673 |
| TBX2 | T-box 2 | -4.08968 |
| C2CD5 | C2 calcium-dependent domain containing 5 | -3.95537 |
| CD320 | CD320 molecule | -3.86893 |
| TRIB3 | tribbles pseudokinase 3 | -3.74877 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -3.58961 |
| CASP3 | caspase 3, apoptosis-related cysteine peptidase | -3.57527 |
| GNAS | GNAS complex locus | -3.27611 |
| RGS2 | regulator of G-protein signaling 2 | -3.23026 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -3.10637 |
| GLOD4 | glyoxalase domain containing 4 | -2.96935 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | -2.8769 |
| TRAPPC6A | trafficking protein particle complex 6A | -2.85599 |
| VDAC1 | voltage-dependent anion channel 1 | -2.78783 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -2.7864 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -2.74643 |
| EIF5 | eukaryotic translation initiation factor 5 | -2.65567 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | -2.56427 |
| SPAG4 | sperm associated antigen 4 | -2.53152 |
| FAIM | Fas apoptotic inhibitory molecule | -2.50533 |
| ZNF586 | zinc finger protein 586 | -2.26471 |
| ZNF32 | zinc finger protein 32 | -2.238 |
| POGK | pogo transposable element with KRAB domain | -2.21563 |
| MAPK13 | mitogen-activated protein kinase 13 | -2.18541 |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 | -2.16958 |
| NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon | -2.14039 |
| SCCPDH | saccharopine dehydrogenase (putative) | -2.0848 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) | -2.03366 |
| NLRP4 | NLR family, pyrin domain containing 4 | -2.03112 |
| DENND1B | DENN/MADD domain containing 1B | -2.00674 |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 | -2.00122 |
