CRCGN010_HEPG2_24H:K18 Gene Set
Genes
44 genes differentially expressed following the CRCGN010_HEPG2_24H:K18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
PHKG2
|
phosphorylase kinase, gamma 2 (testis)
|
5.27457
|
|
LOC122526780
|
uncharacterized LOC122526780
|
5.16257
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
4.68417
|
|
CYCS
|
cytochrome c, somatic
|
3.97623
|
|
PPP1R13B
|
protein phosphatase 1, regulatory subunit 13B
|
3.81562
|
|
IDE
|
insulin-degrading enzyme
|
3.70345
|
|
MAP7
|
microtubule-associated protein 7
|
3.55661
|
|
KDM5A
|
lysine (K)-specific demethylase 5A
|
3.26825
|
|
CSK
|
c-src tyrosine kinase
|
2.98624
|
|
NOTCH1
|
notch 1
|
2.91759
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
2.77319
|
|
PLS1
|
plastin 1
|
2.69991
|
|
LCN2
|
lipocalin 2
|
2.65236
|
|
CYB561
|
cytochrome b561
|
2.62053
|
|
C2CD2
|
C2 calcium-dependent domain containing 2
|
2.48642
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.44713
|
|
ATP11B
|
ATPase, class VI, type 11B
|
2.40171
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
2.36863
|
|
E2F2
|
E2F transcription factor 2
|
2.27968
|
|
NOP53
|
NOP53 ribosome biogenesis factor
|
2.25939
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.1481
|
|
PDLIM1
|
PDZ and LIM domain 1
|
2.13448
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-7.29953
|
|
CCNB2
|
cyclin B2
|
-6.82306
|
|
ZNF586
|
zinc finger protein 586
|
-5.73903
|
|
GADD45A
|
growth arrest and DNA-damage-inducible, alpha
|
-5.36055
|
|
HACD3
|
3-hydroxyacyl-CoA dehydratase 3
|
-5.15003
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-5.00886
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-4.81721
|
|
PLK1
|
polo-like kinase 1
|
-4.44695
|
|
TLR4
|
toll-like receptor 4
|
-3.97571
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-3.59604
|
|
RFC2
|
replication factor C (activator 1) 2, 40kDa
|
-3.27226
|
|
NR2F6
|
nuclear receptor subfamily 2, group F, member 6
|
-3.26492
|
|
DERA
|
deoxyribose-phosphate aldolase (putative)
|
-3.26424
|
|
PCCB
|
propionyl CoA carboxylase, beta polypeptide
|
-2.77142
|
|
FAIM
|
Fas apoptotic inhibitory molecule
|
-2.57279
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-2.56383
|
|
IDH1
|
isocitrate dehydrogenase 1 (NADP+), soluble
|
-2.4349
|
|
ITGB1BP1
|
integrin beta 1 binding protein 1
|
-2.37165
|
|
DUSP6
|
dual specificity phosphatase 6
|
-2.23913
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.22461
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-2.14488
|
|
LOC124907782
|
dual specificity protein phosphatase 22
|
-2.01853
|
