CRCGN010_HEPG2_24H:K19 Gene Set
Genes
46 genes differentially expressed following the CRCGN010_HEPG2_24H:K19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
LCN2
|
lipocalin 2
|
7.32038
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
6.88255
|
|
STK10
|
serine/threonine kinase 10
|
6.34585
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
6.2566
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
4.53139
|
|
SFTPB
|
surfactant protein B
|
4.40475
|
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
4.03378
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
3.7508
|
|
INTS3
|
integrator complex subunit 3
|
3.63448
|
|
MYLK
|
myosin light chain kinase
|
3.52249
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
3.41633
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
3.27125
|
|
PPP1R13B
|
protein phosphatase 1, regulatory subunit 13B
|
3.17802
|
|
CSK
|
c-src tyrosine kinase
|
3.14079
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
2.96204
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
2.95577
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
2.80366
|
|
CBR3
|
carbonyl reductase 3
|
2.75362
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
2.7236
|
|
UBQLN2
|
ubiquilin 2
|
2.60801
|
|
STIMATE
|
STIM activating enhancer
|
2.59755
|
|
BAD
|
BCL2-associated agonist of cell death
|
2.2632
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.24135
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
2.20357
|
|
DNAJC15
|
DnaJ (Hsp40) homolog, subfamily C, member 15
|
2.142
|
|
PLSCR1
|
phospholipid scramblase 1
|
2.07538
|
|
TXNL4B
|
thioredoxin-like 4B
|
2.03164
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-6.69249
|
|
TLCD3A
|
TLC domain containing 3A
|
-5.64392
|
|
TLR4
|
toll-like receptor 4
|
-4.86087
|
|
TP53BP2
|
tumor protein p53 binding protein 2
|
-3.63669
|
|
C2CD5
|
C2 calcium-dependent domain containing 5
|
-3.57171
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-3.45119
|
|
HMG20B
|
high mobility group 20B
|
-3.43493
|
|
CDC20
|
cell division cycle 20
|
-3.3875
|
|
ARID5B
|
AT rich interactive domain 5B (MRF1-like)
|
-3.29777
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.22624
|
|
RALA
|
v-ral simian leukemia viral oncogene homolog A (ras related)
|
-2.76772
|
|
WDR7
|
WD repeat domain 7
|
-2.69634
|
|
RFC2
|
replication factor C (activator 1) 2, 40kDa
|
-2.6604
|
|
ZNF586
|
zinc finger protein 586
|
-2.32768
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-2.07035
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.04108
|
|
SNX11
|
sorting nexin 11
|
-2.0307
|
|
ZSCAN26
|
zinc finger and SCAN domain containing 26
|
-2.02789
|
|
RWDD2A
|
RWD domain containing 2A
|
-2.01309
|
