| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | p,p'-dichlorodiphenyl sulfone 20.2 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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59 genes differentially expressed following the CRCGN010_HEPG2_24H:K20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 8.07712 |
| GSTZ1 | glutathione S-transferase zeta 1 | 6.4744 |
| UBQLN2 | ubiquilin 2 | 6.16534 |
| PPARG | peroxisome proliferator-activated receptor gamma | 6.14967 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 4.57561 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | 4.43836 |
| CRTAP | cartilage associated protein | 4.28662 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 4.10443 |
| NMU | neuromedin U | 3.91139 |
| TREM1 | triggering receptor expressed on myeloid cells 1 | 3.86295 |
| NOSIP | nitric oxide synthase interacting protein | 3.77561 |
| EVL | Enah/Vasp-like | 3.52682 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 3.31781 |
| DIPK1A | divergent protein kinase domain 1A | 3.1899 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit | 2.98985 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | 2.84514 |
| PHKG2 | phosphorylase kinase, gamma 2 (testis) | 2.66946 |
| HEBP1 | heme binding protein 1 | 2.6443 |
| MCUR1 | mitochondrial calcium uniporter regulator 1 | 2.3611 |
| PNKP | polynucleotide kinase 3'-phosphatase | 2.35482 |
| MAPKAPK5 | mitogen-activated protein kinase-activated protein kinase 5 | 2.33372 |
| STAP2 | signal transducing adaptor family member 2 | 2.30818 |
| AMDHD2 | amidohydrolase domain containing 2 | 2.28616 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 2.21513 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 2.05732 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TRIB3 | tribbles pseudokinase 3 | -5.41411 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -4.85625 |
| GOLT1B | golgi transport 1B | -4.23228 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -4.19582 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -4.11237 |
| GNAS | GNAS complex locus | -3.9637 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -3.87996 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | -3.83839 |
| ZNF586 | zinc finger protein 586 | -3.7424 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -3.66358 |
| CCNB1 | cyclin B1 | -3.53699 |
| UGDH | UDP-glucose 6-dehydrogenase | -3.29208 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -3.23186 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -3.05318 |
| VAT1 | vesicle amine transport 1 | -3.02909 |
| STUB1 | STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase | -2.97464 |
| SLC35F2 | solute carrier family 35, member F2 | -2.91054 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -2.86641 |
| YME1L1 | YME1-like 1 ATPase | -2.8121 |
| DERA | deoxyribose-phosphate aldolase (putative) | -2.79896 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | -2.62269 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -2.588 |
| CD320 | CD320 molecule | -2.53122 |
| STX4 | syntaxin 4 | -2.50771 |
| MYL9 | myosin, light chain 9, regulatory | -2.43467 |
| CD58 | CD58 molecule | -2.43001 |
| PCNA | proliferating cell nuclear antigen | -2.19487 |
| CCNB2 | cyclin B2 | -2.1465 |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) | -2.13873 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -2.12604 |
| DIPK2B | divergent protein kinase domain 2B | -2.08637 |
| DDIT4 | DNA-damage-inducible transcript 4 | -2.05616 |
| PGM5 | phosphoglucomutase 5 | -2.03457 |
| SNX11 | sorting nexin 11 | -2.02999 |
