| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | p,p'-dichlorodiphenyl sulfone 10.1 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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70 genes differentially expressed following the CRCGN010_HEPG2_24H:K21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RPP38 | ribonuclease P/MRP 38kDa subunit | 8.22162 |
| MOK | MOK protein kinase | 7.71733 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 6.62994 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 6.47539 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 5.70379 |
| NOTCH1 | notch 1 | 5.12061 |
| LPAR2 | lysophosphatidic acid receptor 2 | 4.94899 |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 | 4.89997 |
| MEST | mesoderm specific transcript | 4.70441 |
| PPARG | peroxisome proliferator-activated receptor gamma | 4.70284 |
| GPATCH8 | G patch domain containing 8 | 4.69439 |
| MINDY1 | MINDY lysine 48 deubiquitinase 1 | 4.68596 |
| PRKCD | protein kinase C, delta | 4.60064 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 4.10124 |
| MAP7 | microtubule-associated protein 7 | 3.88168 |
| TATDN2 | TatD DNase domain containing 2 | 3.59699 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 3.31889 |
| SMIM40 | small integral membrane protein 40 | 3.25894 |
| NOSIP | nitric oxide synthase interacting protein | 2.93575 |
| STIMATE | STIM activating enhancer | 2.83227 |
| SOCS2 | suppressor of cytokine signaling 2 | 2.76177 |
| ATP11B | ATPase, class VI, type 11B | 2.71747 |
| SATB1 | SATB homeobox 1 | 2.68765 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 2.59434 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 2.58586 |
| CDC45 | cell division cycle 45 | 2.53277 |
| CHMP6 | charged multivesicular body protein 6 | 2.52746 |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta | 2.47188 |
| ZFP36 | ZFP36 ring finger protein | 2.39967 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | 2.38031 |
| CRTC3 | CREB regulated transcription coactivator 3 | 2.33159 |
| CYCS | cytochrome c, somatic | 2.32844 |
| PWP2 | PWP2 periodic tryptophan protein homolog (yeast) | 2.26198 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 2.24692 |
| TREM1 | triggering receptor expressed on myeloid cells 1 | 2.24032 |
| CEP57 | centrosomal protein 57kDa | 2.21715 |
| BRD7 | bromodomain containing 7 | 2.16265 |
| ITM2A | integral membrane protein 2A | 2.07939 |
| CCNF | cyclin F | 2.04524 |
| GALNT12 | polypeptide N-acetylgalactosaminyltransferase 12 | 2.02637 |
| ACIN1 | apoptotic chromatin condensation inducer 1 | 2.01318 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -8.19872 |
| CCNB2 | cyclin B2 | -7.38914 |
| TLR4 | toll-like receptor 4 | -6.79271 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -5.08514 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -5.0726 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -4.82415 |
| TSEN2 | TSEN2 tRNA splicing endonuclease subunit | -4.30068 |
| ZNF586 | zinc finger protein 586 | -3.21904 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -3.0491 |
| YME1L1 | YME1-like 1 ATPase | -3.00813 |
| WASHC4 | WASH complex subunit 4 | -2.88273 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | -2.5298 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -2.51924 |
| SPAG7 | sperm associated antigen 7 | -2.48099 |
| SOAT2 | sterol O-acyltransferase 2 | -2.46573 |
| MAPK13 | mitogen-activated protein kinase 13 | -2.32867 |
| MS4A1 | membrane-spanning 4-domains, subfamily A, member 1 | -2.31773 |
| EDEM1 | ER degradation enhancer, mannosidase alpha-like 1 | -2.28298 |
| ARSJ | arylsulfatase family, member J | -2.27918 |
| GNAS | GNAS complex locus | -2.2195 |
| RNF167 | ring finger protein 167 | -2.20184 |
| ADI1 | acireductone dioxygenase 1 | -2.1824 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -2.18138 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -2.14568 |
| LY86 | lymphocyte antigen 86 | -2.11264 |
| NT5DC3 | 5'-nucleotidase domain containing 3 | -2.09999 |
| UBE2W | ubiquitin-conjugating enzyme E2W (putative) | -2.07194 |
| SNX11 | sorting nexin 11 | -2.03922 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -2.02008 |
