| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | p,p'-dichlorodiphenyl sulfone 2.52 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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68 genes differentially expressed following the CRCGN010_HEPG2_24H:K23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RPP38 | ribonuclease P/MRP 38kDa subunit | 6.89295 |
| STIMATE | STIM activating enhancer | 6.79505 |
| CSK | c-src tyrosine kinase | 4.37396 |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 | 4.16026 |
| EPHB2 | EPH receptor B2 | 4.01811 |
| PPARG | peroxisome proliferator-activated receptor gamma | 3.93679 |
| LCN2 | lipocalin 2 | 3.9003 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 3.88356 |
| NOSIP | nitric oxide synthase interacting protein | 3.66321 |
| TAC4 | tachykinin 4 (hemokinin) | 3.65143 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 3.58591 |
| MAMLD1 | mastermind-like domain containing 1 | 3.52891 |
| MEST | mesoderm specific transcript | 3.35339 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 3.33269 |
| CYCS | cytochrome c, somatic | 3.23731 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 3.20819 |
| TIMM17B | translocase of inner mitochondrial membrane 17 homolog B (yeast) | 3.20279 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 2.91301 |
| E2F2 | E2F transcription factor 2 | 2.82333 |
| GSTZ1 | glutathione S-transferase zeta 1 | 2.78308 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 2.70781 |
| HEBP1 | heme binding protein 1 | 2.67736 |
| NOTCH1 | notch 1 | 2.67277 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 2.63584 |
| SMARCD2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 | 2.51678 |
| FAM171A1 | family with sequence similarity 171, member A1 | 2.39218 |
| SCRN1 | secernin 1 | 2.37527 |
| CHMP6 | charged multivesicular body protein 6 | 2.28811 |
| AFM | afamin | 2.19013 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 2.15126 |
| SLC27A3 | solute carrier family 27 (fatty acid transporter), member 3 | 2.1303 |
| CAV3 | caveolin 3 | 2.11867 |
| ZNF93 | zinc finger protein 93 | 2.09442 |
| WNT10B | wingless-type MMTV integration site family, member 10B | 2.09374 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 2.03781 |
| MOG | myelin oligodendrocyte glycoprotein | 2.01596 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -6.85111 |
| CCNB2 | cyclin B2 | -6.72488 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -5.16176 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -4.2426 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -4.08313 |
| CDC25B | cell division cycle 25B | -4.04653 |
| COG7 | component of oligomeric golgi complex 7 | -3.89455 |
| TLR4 | toll-like receptor 4 | -3.80393 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -3.78294 |
| FASTKD5 | FAST kinase domains 5 | -3.75153 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -3.62788 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -3.16837 |
| MAPK13 | mitogen-activated protein kinase 13 | -3.1324 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -3.09755 |
| TUBB6 | tubulin, beta 6 class V | -2.97827 |
| PCNA | proliferating cell nuclear antigen | -2.81437 |
| WDR7 | WD repeat domain 7 | -2.73384 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -2.69799 |
| KDM3A | lysine (K)-specific demethylase 3A | -2.68359 |
| DNTTIP2 | deoxynucleotidyltransferase, terminal, interacting protein 2 | -2.66965 |
| LDHD | lactate dehydrogenase D | -2.64693 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | -2.62926 |
| RAI14 | retinoic acid induced 14 | -2.62452 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -2.61005 |
| TCTN1 | tectonic family member 1 | -2.60826 |
| VDAC1 | voltage-dependent anion channel 1 | -2.56592 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -2.47319 |
| TLCD3A | TLC domain containing 3A | -2.33481 |
| ARL2BP | ADP-ribosylation factor-like 2 binding protein | -2.31702 |
| RGS2 | regulator of G-protein signaling 2 | -2.15351 |
| IDH1 | isocitrate dehydrogenase 1 (NADP+), soluble | -2.15154 |
| CRELD2 | cysteine-rich with EGF-like domains 2 | -2.00353 |
