| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | p,p'-dichlorodiphenyl sulfone 1.26 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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48 genes differentially expressed following the CRCGN010_HEPG2_24H:K24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 7.24904 |
| PEX11A | peroxisomal biogenesis factor 11 alpha | 5.67826 |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 | 4.91154 |
| ATP11B | ATPase, class VI, type 11B | 4.6582 |
| SFTPB | surfactant protein B | 3.65656 |
| NOSIP | nitric oxide synthase interacting protein | 3.44612 |
| DHX29 | DEAH (Asp-Glu-Ala-His) box polypeptide 29 | 3.39401 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 3.08243 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 3.04129 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 2.96104 |
| MYLK | myosin light chain kinase | 2.95641 |
| GPER1 | G protein-coupled estrogen receptor 1 | 2.76028 |
| POLG2 | polymerase (DNA directed), gamma 2, accessory subunit | 2.71501 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 2.66903 |
| TBXA2R | thromboxane A2 receptor | 2.63171 |
| LOC122526780 | uncharacterized LOC122526780 | 2.5803 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 2.41341 |
| SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) | 2.39512 |
| ABHD6 | abhydrolase domain containing 6 | 2.36532 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 2.27 |
| PF4 | platelet factor 4 | 2.17891 |
| AKT1 | v-akt murine thymoma viral oncogene homolog 1 | 2.13964 |
| EPHA2 | EPH receptor A2 | 2.06845 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | 2.06256 |
| RPA3 | replication protein A3, 14kDa | 2.02876 |
| TRIM13 | tripartite motif containing 13 | 2.01556 |
| Symbol | Name | Standardized Value |
|---|---|---|
| OXA1L | oxidase (cytochrome c) assembly 1-like | -6.06339 |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) | -5.41298 |
| KDM3A | lysine (K)-specific demethylase 3A | -5.19268 |
| VAT1 | vesicle amine transport 1 | -4.77849 |
| LDHD | lactate dehydrogenase D | -4.77345 |
| PCNA | proliferating cell nuclear antigen | -4.4865 |
| HMG20B | high mobility group 20B | -3.44496 |
| MAPK13 | mitogen-activated protein kinase 13 | -3.41782 |
| WASHC4 | WASH complex subunit 4 | -3.2381 |
| FBXL12 | F-box and leucine-rich repeat protein 12 | -3.17616 |
| COG2 | component of oligomeric golgi complex 2 | -3.10482 |
| LOC124907782 | dual specificity protein phosphatase 22 | -2.98895 |
| RPN1 | ribophorin I | -2.75465 |
| PLK1 | polo-like kinase 1 | -2.61437 |
| THAP11 | THAP domain containing 11 | -2.3014 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -2.21881 |
| CCNB1 | cyclin B1 | -2.20521 |
| CCNB2 | cyclin B2 | -2.18369 |
| CCDC86 | coiled-coil domain containing 86 | -2.18182 |
| ILF2 | interleukin enhancer binding factor 2 | -2.14514 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -2.14027 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | -2.01117 |
