CRCGN010_HEPG2_24H:L01 Gene Set
Genes
38 genes differentially expressed following the CRCGN010_HEPG2_24H:L01 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CHN1
|
chimerin 1
|
4.67828
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
4.59453
|
|
SFTPB
|
surfactant protein B
|
4.39891
|
|
MSRA
|
methionine sulfoxide reductase A
|
4.25679
|
|
MYLK
|
myosin light chain kinase
|
3.81487
|
|
PMM2
|
phosphomannomutase 2
|
3.58338
|
|
CYCS
|
cytochrome c, somatic
|
3.50534
|
|
CDPF1
|
cysteine-rich, DPF motif domain containing 1
|
3.43778
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
3.36363
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
3.27592
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
3.21229
|
|
MAP7
|
microtubule-associated protein 7
|
3.12421
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
2.98793
|
|
SLC25A46
|
solute carrier family 25, member 46
|
2.7963
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.77276
|
|
ZNF589
|
zinc finger protein 589
|
2.697
|
|
GATA3
|
GATA binding protein 3
|
2.63669
|
|
LOC122526780
|
uncharacterized LOC122526780
|
2.61049
|
|
CNPY3
|
canopy FGF signaling regulator 3
|
2.53916
|
|
HMOX1
|
heme oxygenase 1
|
2.42898
|
|
EGF
|
epidermal growth factor
|
2.24498
|
|
MOK
|
MOK protein kinase
|
2.00838
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ZNF586
|
zinc finger protein 586
|
-8.53184
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-5.62357
|
|
ISOC1
|
isochorismatase domain containing 1
|
-5.28479
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-4.457
|
|
LDHD
|
lactate dehydrogenase D
|
-4.27368
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-4.10554
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.58513
|
|
TLR4
|
toll-like receptor 4
|
-3.23359
|
|
PECR
|
peroxisomal trans-2-enoyl-CoA reductase
|
-2.87861
|
|
DNAJB6
|
DnaJ (Hsp40) homolog, subfamily B, member 6
|
-2.60634
|
|
ZNF134
|
zinc finger protein 134
|
-2.39322
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-2.37931
|
|
DDIT4
|
DNA-damage-inducible transcript 4
|
-2.26121
|
|
PPOX
|
protoporphyrinogen oxidase
|
-2.20809
|
|
CRELD2
|
cysteine-rich with EGF-like domains 2
|
-2.13766
|
|
FURIN
|
furin (paired basic amino acid cleaving enzyme)
|
-2.13699
|
