CRCGN010_HEPG2_24H:L02 Gene Set
Genes
43 genes differentially expressed following the CRCGN010_HEPG2_24H:L02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
8.26995
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
5.09448
|
|
SUV39H1
|
suppressor of variegation 3-9 homolog 1 (Drosophila)
|
4.97676
|
|
MYLK
|
myosin light chain kinase
|
4.82714
|
|
MSRA
|
methionine sulfoxide reductase A
|
4.35546
|
|
NR3C1
|
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
|
3.95278
|
|
UBQLN2
|
ubiquilin 2
|
3.93449
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.53698
|
|
MAP7
|
microtubule-associated protein 7
|
2.98669
|
|
ADGRG1
|
adhesion G protein-coupled receptor G1
|
2.97842
|
|
PSMB8
|
proteasome (prosome, macropain) subunit, beta type, 8
|
2.90956
|
|
SMIM40
|
small integral membrane protein 40
|
2.72121
|
|
SFTPB
|
surfactant protein B
|
2.57099
|
|
TNIP1
|
TNFAIP3 interacting protein 1
|
2.4506
|
|
CYCS
|
cytochrome c, somatic
|
2.3324
|
|
SOCS2
|
suppressor of cytokine signaling 2
|
2.2657
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
2.2399
|
|
PHKA1
|
phosphorylase kinase, alpha 1 (muscle)
|
2.211
|
|
CDC45
|
cell division cycle 45
|
2.14508
|
|
LAMTOR3
|
late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
|
2.12553
|
|
SLC9B2
|
solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2
|
2.09204
|
|
CHN1
|
chimerin 1
|
2.0383
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
TLCD3A
|
TLC domain containing 3A
|
-6.28931
|
|
USP6NL
|
USP6 N-terminal like
|
-5.26022
|
|
RPN1
|
ribophorin I
|
-4.61579
|
|
SLC25A13
|
solute carrier family 25 (aspartate/glutamate carrier), member 13
|
-4.55811
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-4.4382
|
|
ZNF586
|
zinc finger protein 586
|
-4.37677
|
|
RAI14
|
retinoic acid induced 14
|
-4.01917
|
|
TRIB3
|
tribbles pseudokinase 3
|
-4.00936
|
|
PPP2R3C
|
protein phosphatase 2, regulatory subunit B'', gamma
|
-3.57235
|
|
CAB39
|
calcium binding protein 39
|
-3.54344
|
|
TLR4
|
toll-like receptor 4
|
-3.36397
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.75199
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.71607
|
|
TLE1
|
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
|
-2.52186
|
|
COPG1
|
coatomer protein complex, subunit gamma 1
|
-2.48942
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-2.40126
|
|
HSPBAP1
|
HSPB (heat shock 27kDa) associated protein 1
|
-2.3849
|
|
ZFC3H1
|
zinc finger, C3H1-type containing
|
-2.18403
|
|
DNAJC17
|
DnaJ (Hsp40) homolog, subfamily C, member 17
|
-2.17036
|
|
RFC2
|
replication factor C (activator 1) 2, 40kDa
|
-2.14925
|
|
KIFBP
|
kinesin family binding protein
|
-2.04197
|
