CRCGN010_HEPG2_24H:L04 Gene Set
Genes
59 genes differentially expressed following the CRCGN010_HEPG2_24H:L04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
6.82097
|
|
PHKG2
|
phosphorylase kinase, gamma 2 (testis)
|
5.08004
|
|
STIMATE
|
STIM activating enhancer
|
5.0098
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
4.38003
|
|
STK10
|
serine/threonine kinase 10
|
4.34461
|
|
MAP7
|
microtubule-associated protein 7
|
4.10086
|
|
HOXA10
|
homeobox A10
|
4.06614
|
|
EPN2
|
epsin 2
|
3.99764
|
|
DYRK3
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
|
3.67193
|
|
NOTCH1
|
notch 1
|
3.50606
|
|
PLS1
|
plastin 1
|
3.43665
|
|
RXYLT1
|
ribitol xylosyltransferase 1
|
3.43478
|
|
MYBL2
|
v-myb avian myeloblastosis viral oncogene homolog-like 2
|
3.37893
|
|
STAP2
|
signal transducing adaptor family member 2
|
2.9918
|
|
CHN1
|
chimerin 1
|
2.82112
|
|
RFNG
|
RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
|
2.72035
|
|
PPP1R13B
|
protein phosphatase 1, regulatory subunit 13B
|
2.59625
|
|
UBQLN2
|
ubiquilin 2
|
2.57946
|
|
SRC
|
SRC proto-oncogene, non-receptor tyrosine kinase
|
2.56502
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
2.52455
|
|
EVL
|
Enah/Vasp-like
|
2.26345
|
|
PER3
|
period circadian clock 3
|
2.14546
|
|
CHMP6
|
charged multivesicular body protein 6
|
2.14221
|
|
CEP57
|
centrosomal protein 57kDa
|
2.1385
|
|
CSK
|
c-src tyrosine kinase
|
2.12594
|
|
CROT
|
carnitine O-octanoyltransferase
|
2.12179
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
2.11213
|
|
CD40
|
CD40 molecule, TNF receptor superfamily member 5
|
2.1075
|
|
TNIP2
|
TNFAIP3 interacting protein 2
|
2.07941
|
|
BRINP3
|
bone morphogenetic protein/retinoic acid inducible neural-specific 3
|
2.03958
|
|
MREG
|
melanoregulin
|
2.00566
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-7.40389
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-7.36119
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-7.31431
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-7.29687
|
|
CCNB2
|
cyclin B2
|
-6.66422
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-5.62773
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-5.078
|
|
PLK1
|
polo-like kinase 1
|
-4.94893
|
|
PCCB
|
propionyl CoA carboxylase, beta polypeptide
|
-4.76583
|
|
ITFG1
|
integrin alpha FG-GAP repeat containing 1
|
-3.98061
|
|
PLEKHJ1
|
pleckstrin homology domain containing, family J member 1
|
-3.81695
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-3.69031
|
|
CCNB1
|
cyclin B1
|
-3.54492
|
|
TLE1
|
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
|
-3.3409
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-3.06183
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.99047
|
|
C2CD5
|
C2 calcium-dependent domain containing 5
|
-2.96972
|
|
TES
|
testin LIM domain protein
|
-2.80677
|
|
CD320
|
CD320 molecule
|
-2.68192
|
|
VDAC1
|
voltage-dependent anion channel 1
|
-2.57834
|
|
GOLT1B
|
golgi transport 1B
|
-2.57237
|
|
TLR4
|
toll-like receptor 4
|
-2.53031
|
|
SLC35B1
|
solute carrier family 35, member B1
|
-2.34304
|
|
ZNF586
|
zinc finger protein 586
|
-2.14028
|
|
SLC2A14
|
solute carrier family 2 (facilitated glucose transporter), member 14
|
-2.12705
|
|
STEAP3
|
STEAP family member 3, metalloreductase
|
-2.10522
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.06724
|
|
RBM34
|
RNA binding motif protein 34
|
-2.06162
|
