CRCGN010_HEPG2_24H:L06 Gene Set
Genes
52 genes differentially expressed following the CRCGN010_HEPG2_24H:L06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
SQOR
|
sulfide quinone oxidoreductase
|
8.59094
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
4.5796
|
|
UBQLN2
|
ubiquilin 2
|
4.41109
|
|
PRR15L
|
proline rich 15-like
|
3.81175
|
|
MSRA
|
methionine sulfoxide reductase A
|
3.72891
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
3.61604
|
|
E2F2
|
E2F transcription factor 2
|
3.59367
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
3.19679
|
|
RAB11FIP2
|
RAB11 family interacting protein 2 (class I)
|
3.05509
|
|
FPGS
|
folylpolyglutamate synthase
|
3.04533
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
3.01008
|
|
CXCR4
|
chemokine (C-X-C motif) receptor 4
|
2.93864
|
|
BAD
|
BCL2-associated agonist of cell death
|
2.82502
|
|
CSK
|
c-src tyrosine kinase
|
2.77927
|
|
GPATCH8
|
G patch domain containing 8
|
2.508
|
|
ENY2
|
enhancer of yellow 2 homolog (Drosophila)
|
2.49911
|
|
MTERF3
|
mitochondrial transcription termination factor 3
|
2.46974
|
|
CYCS
|
cytochrome c, somatic
|
2.43758
|
|
SFTPB
|
surfactant protein B
|
2.41604
|
|
MAST2
|
microtubule associated serine/threonine kinase 2
|
2.40314
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
2.34874
|
|
ZFP36
|
ZFP36 ring finger protein
|
2.23082
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
2.17194
|
|
CYB561
|
cytochrome b561
|
2.15062
|
|
VGLL4
|
vestigial-like family member 4
|
2.09145
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
2.04551
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-5.00714
|
|
UBE3C
|
ubiquitin protein ligase E3C
|
-4.88468
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.85142
|
|
CCNB2
|
cyclin B2
|
-4.76075
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-4.67265
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-4.54378
|
|
PCNA
|
proliferating cell nuclear antigen
|
-3.72982
|
|
TLCD3A
|
TLC domain containing 3A
|
-3.64691
|
|
POLR2I
|
polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
|
-3.46679
|
|
TLE1
|
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
|
-3.4435
|
|
TM9SF3
|
transmembrane 9 superfamily member 3
|
-3.34654
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-3.26154
|
|
DDX3Y
|
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
|
-3.24872
|
|
LDHD
|
lactate dehydrogenase D
|
-3.04683
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-2.99196
|
|
STAMBP
|
STAM binding protein
|
-2.98165
|
|
TBCB
|
tubulin folding cofactor B
|
-2.95321
|
|
ZNF146
|
zinc finger protein 146
|
-2.71916
|
|
VDAC1
|
voltage-dependent anion channel 1
|
-2.6898
|
|
TMEM147
|
transmembrane protein 147
|
-2.44105
|
|
TLR4
|
toll-like receptor 4
|
-2.41412
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-2.37319
|
|
GPATCH1
|
G patch domain containing 1
|
-2.34938
|
|
LRFN3
|
leucine rich repeat and fibronectin type III domain containing 3
|
-2.07306
|
|
SDHAF1
|
succinate dehydrogenase complex assembly factor 1
|
-2.03006
|
|
COX6B1
|
cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous)
|
-2.00611
|
