CRCGN010_HEPG2_24H:L07 Gene Set
Genes
54 genes differentially expressed following the CRCGN010_HEPG2_24H:L07 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
GSTZ1
|
glutathione S-transferase zeta 1
|
5.85279
|
|
CBR1
|
carbonyl reductase 1
|
5.65099
|
|
E2F2
|
E2F transcription factor 2
|
5.13459
|
|
UBQLN2
|
ubiquilin 2
|
4.6538
|
|
HYOU1
|
hypoxia up-regulated 1
|
3.62692
|
|
BPHL
|
biphenyl hydrolase-like (serine hydrolase)
|
3.39688
|
|
EVL
|
Enah/Vasp-like
|
3.11503
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
3.0608
|
|
NOTCH1
|
notch 1
|
2.8491
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
2.7375
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
2.66903
|
|
STK10
|
serine/threonine kinase 10
|
2.65316
|
|
CRTAP
|
cartilage associated protein
|
2.65174
|
|
CCNF
|
cyclin F
|
2.63255
|
|
RPS6KA1
|
ribosomal protein S6 kinase, 90kDa, polypeptide 1
|
2.62557
|
|
PRKCH
|
protein kinase C, eta
|
2.56056
|
|
DYRK3
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
|
2.3333
|
|
ABHD6
|
abhydrolase domain containing 6
|
2.30193
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
2.22748
|
|
DDX10
|
DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
|
2.21896
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
2.19016
|
|
CEP57
|
centrosomal protein 57kDa
|
2.15239
|
|
DRAP1
|
DR1-associated protein 1 (negative cofactor 2 alpha)
|
2.14077
|
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
2.12426
|
|
PXMP2
|
peroxisomal membrane protein 2, 22kDa
|
2.11694
|
|
GARRE1
|
granule associated Rac and RHOG effector 1
|
2.06767
|
|
HSPA1A
|
heat shock 70kDa protein 1A
|
2.043
|
|
TDP1
|
tyrosyl-DNA phosphodiesterase 1
|
2.00272
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ZNF586
|
zinc finger protein 586
|
-9.17081
|
|
TRIB3
|
tribbles pseudokinase 3
|
-7.15348
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-7.06421
|
|
ADI1
|
acireductone dioxygenase 1
|
-7.03014
|
|
VDAC1
|
voltage-dependent anion channel 1
|
-5.76242
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-5.2281
|
|
YME1L1
|
YME1-like 1 ATPase
|
-5.0156
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-4.70321
|
|
LDHD
|
lactate dehydrogenase D
|
-4.6537
|
|
CD58
|
CD58 molecule
|
-4.60976
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-4.51652
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-3.66974
|
|
TLR4
|
toll-like receptor 4
|
-3.38955
|
|
PCK2
|
phosphoenolpyruvate carboxykinase 2 (mitochondrial)
|
-2.98602
|
|
ITGB1BP1
|
integrin beta 1 binding protein 1
|
-2.83009
|
|
PCMT1
|
protein-L-isoaspartate (D-aspartate) O-methyltransferase
|
-2.69703
|
|
TM9SF3
|
transmembrane 9 superfamily member 3
|
-2.6003
|
|
ITFG1
|
integrin alpha FG-GAP repeat containing 1
|
-2.50167
|
|
GFPT1
|
glutamine--fructose-6-phosphate transaminase 1
|
-2.39317
|
|
ARID5B
|
AT rich interactive domain 5B (MRF1-like)
|
-2.35148
|
|
SNX11
|
sorting nexin 11
|
-2.33641
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
-2.28071
|
|
FOXN2
|
forkhead box N2
|
-2.16469
|
|
SQSTM1
|
sequestosome 1
|
-2.0655
|
|
ARHGEF12
|
Rho guanine nucleotide exchange factor (GEF) 12
|
-2.06252
|
|
WASHC4
|
WASH complex subunit 4
|
-2.01811
|
