CRCGN010_HEPG2_24H:L09 Gene Set
Genes
55 genes differentially expressed following the CRCGN010_HEPG2_24H:L09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
PLSCR1
|
phospholipid scramblase 1
|
5.53845
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
5.4507
|
|
NOTCH1
|
notch 1
|
5.0166
|
|
E2F2
|
E2F transcription factor 2
|
4.84398
|
|
PPP1R13B
|
protein phosphatase 1, regulatory subunit 13B
|
4.8106
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
4.7558
|
|
MSRA
|
methionine sulfoxide reductase A
|
4.5796
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
4.53322
|
|
CHMP6
|
charged multivesicular body protein 6
|
4.37796
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
3.94489
|
|
SFTPB
|
surfactant protein B
|
3.57431
|
|
STIMATE
|
STIM activating enhancer
|
3.56382
|
|
SLC75A1
|
solute carrier family 75 member 1
|
3.03706
|
|
NOL3
|
nucleolar protein 3 (apoptosis repressor with CARD domain)
|
2.93505
|
|
UBQLN2
|
ubiquilin 2
|
2.82579
|
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
2.74847
|
|
CCNA1
|
cyclin A1
|
2.6602
|
|
ZFP36
|
ZFP36 ring finger protein
|
2.55663
|
|
BPHL
|
biphenyl hydrolase-like (serine hydrolase)
|
2.49738
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.48746
|
|
GARRE1
|
granule associated Rac and RHOG effector 1
|
2.43872
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
2.36283
|
|
ACTN4
|
actinin, alpha 4
|
2.30922
|
|
BAG3
|
BCL2-associated athanogene 3
|
2.24154
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
2.23921
|
|
ABHD6
|
abhydrolase domain containing 6
|
2.19919
|
|
PCDHB11
|
protocadherin beta 11
|
2.16478
|
|
HSPA1A
|
heat shock 70kDa protein 1A
|
2.06697
|
|
CTR9
|
CTR9, Paf1/RNA polymerase II complex component
|
2.04552
|
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5
|
2.03568
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ZNF586
|
zinc finger protein 586
|
-6.69392
|
|
LDHD
|
lactate dehydrogenase D
|
-5.1033
|
|
MRPS16
|
mitochondrial ribosomal protein S16
|
-5.00408
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-4.92497
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-4.78817
|
|
PCNA
|
proliferating cell nuclear antigen
|
-4.69858
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-4.50991
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-4.39453
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.61788
|
|
TLE1
|
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
|
-3.55502
|
|
NVL
|
nuclear VCP-like
|
-3.51973
|
|
DNM1L
|
dynamin 1-like
|
-3.49412
|
|
FAIM
|
Fas apoptotic inhibitory molecule
|
-3.24286
|
|
CCNB2
|
cyclin B2
|
-3.24191
|
|
TLR4
|
toll-like receptor 4
|
-3.00168
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-2.73512
|
|
FASTKD5
|
FAST kinase domains 5
|
-2.70879
|
|
CCNB1
|
cyclin B1
|
-2.56049
|
|
IFRD2
|
interferon-related developmental regulator 2
|
-2.55423
|
|
ZDHHC6
|
zinc finger, DHHC-type containing 6
|
-2.54613
|
|
PCK2
|
phosphoenolpyruvate carboxykinase 2 (mitochondrial)
|
-2.3723
|
|
TXNRD1
|
thioredoxin reductase 1
|
-2.31713
|
|
EPYC
|
epiphycan
|
-2.09757
|
|
GET1
|
guided entry of tail-anchored proteins factor 1
|
-2.04541
|
|
HROB
|
homologous recombination factor with OB-fold
|
-2.02867
|
