| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | phthalamide 2.51 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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58 genes differentially expressed following the CRCGN010_HEPG2_24H:L11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CHN1 | chimerin 1 | 5.51522 |
| E2F2 | E2F transcription factor 2 | 4.6036 |
| IDE | insulin-degrading enzyme | 4.20257 |
| EPN2 | epsin 2 | 4.18207 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 4.15755 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 3.834 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 3.6824 |
| CNPY3 | canopy FGF signaling regulator 3 | 3.63094 |
| KIF5C | kinesin family member 5C | 3.53939 |
| AMDHD2 | amidohydrolase domain containing 2 | 3.47743 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 3.42926 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | 3.37849 |
| UBQLN2 | ubiquilin 2 | 3.3768 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | 3.2291 |
| HDGFL3 | HDGF like 3 | 3.20866 |
| PPARG | peroxisome proliferator-activated receptor gamma | 3.05457 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 2.76853 |
| DIPK1A | divergent protein kinase domain 1A | 2.67673 |
| DDX42 | DEAD (Asp-Glu-Ala-Asp) box helicase 42 | 2.64656 |
| NUP133 | nucleoporin 133kDa | 2.55239 |
| MAPKAPK5 | mitogen-activated protein kinase-activated protein kinase 5 | 2.52572 |
| GATA2 | GATA binding protein 2 | 2.46536 |
| FZD7 | frizzled class receptor 7 | 2.30162 |
| MOK | MOK protein kinase | 2.25893 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 2.24489 |
| MAP7 | microtubule-associated protein 7 | 2.23777 |
| JADE2 | jade family PHD finger 2 | 2.16949 |
| SLC25A14 | solute carrier family 25 (mitochondrial carrier, brain), member 14 | 2.13345 |
| RFC5 | replication factor C (activator 1) 5, 36.5kDa | 2.08122 |
| PRR36 | proline rich 36 | 2.07115 |
| TVP23B | trans-golgi network vesicle protein 23 homolog B (S. cerevisiae) | 2.02236 |
| RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 | 2.01517 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MRPS2 | mitochondrial ribosomal protein S2 | -8.2709 |
| LDHD | lactate dehydrogenase D | -8.26273 |
| DNM1L | dynamin 1-like | -5.0216 |
| CCNB2 | cyclin B2 | -4.55977 |
| CCDC86 | coiled-coil domain containing 86 | -3.53525 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | -3.3435 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -3.31096 |
| RPIA | ribose 5-phosphate isomerase A | -3.29894 |
| RBM15B | RNA binding motif protein 15B | -3.1854 |
| DCK | deoxycytidine kinase | -3.17697 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | -3.13432 |
| PRPF4 | pre-mRNA processing factor 4 | -3.11931 |
| DDIT4 | DNA-damage-inducible transcript 4 | -3.02763 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -2.9555 |
| DNMT1 | DNA (cytosine-5-)-methyltransferase 1 | -2.79842 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -2.73125 |
| RPS5 | ribosomal protein S5 | -2.7168 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -2.64809 |
| FHL2 | four and a half LIM domains 2 | -2.46613 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | -2.44876 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.40311 |
| LAMB1 | laminin, beta 1 | -2.23484 |
| GNAS | GNAS complex locus | -2.12098 |
| RGS2 | regulator of G-protein signaling 2 | -2.06476 |
| PGCKA1 | PDCD10 and GCKIII kinases associated 1 | -2.04433 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -2.03499 |
