| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | phthalamide 1.26 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
| Downloads & Tools |
81 genes differentially expressed following the CRCGN010_HEPG2_24H:L12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 8.23879 |
| CYCS | cytochrome c, somatic | 5.62157 |
| PHKA1 | phosphorylase kinase, alpha 1 (muscle) | 5.61026 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 5.15762 |
| GSTZ1 | glutathione S-transferase zeta 1 | 5.03592 |
| NMU | neuromedin U | 4.86368 |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta | 4.6525 |
| EAPP | E2F-associated phosphoprotein | 4.65053 |
| LCN2 | lipocalin 2 | 4.28937 |
| EPHB2 | EPH receptor B2 | 4.00008 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 3.89859 |
| BZW2 | basic leucine zipper and W2 domains 2 | 3.82945 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 3.72598 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 3.6641 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | 3.63205 |
| EDN1 | endothelin 1 | 3.62383 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 3.59629 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 3.46981 |
| CBR1 | carbonyl reductase 1 | 3.37076 |
| MAP7 | microtubule-associated protein 7 | 3.04259 |
| CHN1 | chimerin 1 | 2.85971 |
| NNT | nicotinamide nucleotide transhydrogenase | 2.80069 |
| LPAR2 | lysophosphatidic acid receptor 2 | 2.76033 |
| INSIG1 | insulin induced gene 1 | 2.72927 |
| PRR15L | proline rich 15-like | 2.71612 |
| RXYLT1 | ribitol xylosyltransferase 1 | 2.66232 |
| PLS1 | plastin 1 | 2.56342 |
| VPS28 | vacuolar protein sorting 28 homolog (S. cerevisiae) | 2.48403 |
| GPER1 | G protein-coupled estrogen receptor 1 | 2.41833 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | 2.38089 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 2.35918 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 2.34269 |
| HOOK2 | hook microtubule-tethering protein 2 | 2.22768 |
| TENM3 | teneurin transmembrane protein 3 | 2.17022 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 2.14676 |
| AXIN1 | axin 1 | 2.1385 |
| ENY2 | enhancer of yellow 2 homolog (Drosophila) | 2.13451 |
| OXCT1 | 3-oxoacid CoA transferase 1 | 2.11673 |
| PLSCR1 | phospholipid scramblase 1 | 2.0991 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 2.08263 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 2.07177 |
| SPEG | SPEG complex locus | 2.01713 |
| IFI6 | interferon, alpha-inducible protein 6 | 2.00161 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ZNF586 | zinc finger protein 586 | -8.69172 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -6.30736 |
| TLR4 | toll-like receptor 4 | -6.07007 |
| MAPK13 | mitogen-activated protein kinase 13 | -5.23955 |
| FBXO7 | F-box protein 7 | -4.96081 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -4.30443 |
| VAT1 | vesicle amine transport 1 | -4.08558 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -4.01747 |
| LDHD | lactate dehydrogenase D | -3.88421 |
| ADI1 | acireductone dioxygenase 1 | -3.86861 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -3.7729 |
| CCNB2 | cyclin B2 | -3.53478 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -3.50359 |
| POLR2I | polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa | -3.4527 |
| IDH1 | isocitrate dehydrogenase 1 (NADP+), soluble | -3.44759 |
| DERA | deoxyribose-phosphate aldolase (putative) | -3.19282 |
| RFC2 | replication factor C (activator 1) 2, 40kDa | -3.17468 |
| MTA1 | metastasis associated 1 | -2.9602 |
| RNF167 | ring finger protein 167 | -2.87098 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -2.77534 |
| TMEM147 | transmembrane protein 147 | -2.74201 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -2.70017 |
| SESN1 | sestrin 1 | -2.6518 |
| CAPNS1 | calpain, small subunit 1 | -2.56987 |
| ZNF134 | zinc finger protein 134 | -2.50597 |
| ZRSR2 | zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2 | -2.45081 |
| EIF5 | eukaryotic translation initiation factor 5 | -2.35279 |
| NVL | nuclear VCP-like | -2.33041 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -2.30634 |
| USP6NL | USP6 N-terminal like | -2.20483 |
| NR2F6 | nuclear receptor subfamily 2, group F, member 6 | -2.20409 |
| SMC1A | structural maintenance of chromosomes 1A | -2.14875 |
| NTRK1 | neurotrophic tyrosine kinase, receptor, type 1 | -2.1482 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -2.10299 |
| ACAA1 | acetyl-CoA acyltransferase 1 | -2.05059 |
| ADIPOR1 | adiponectin receptor 1 | -2.04713 |
| BAG1 | BCL2-associated athanogene | -2.0392 |
| ZNF780A | zinc finger protein 780A | -2.00147 |
