| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | iq 38.4 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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180 genes differentially expressed following the CRCGN010_HEPG2_24H:L13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 6.60129 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 6.50093 |
| ZFP36 | ZFP36 ring finger protein | 6.46722 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 5.58428 |
| MAP7 | microtubule-associated protein 7 | 4.81594 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 4.81494 |
| EDN1 | endothelin 1 | 4.57492 |
| CYCS | cytochrome c, somatic | 4.56656 |
| CHMP6 | charged multivesicular body protein 6 | 4.29981 |
| PPARG | peroxisome proliferator-activated receptor gamma | 4.26077 |
| E2F2 | E2F transcription factor 2 | 4.0999 |
| HSPA1A | heat shock 70kDa protein 1A | 3.93331 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 3.76583 |
| TAC4 | tachykinin 4 (hemokinin) | 3.67487 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 3.62 |
| MAMLD1 | mastermind-like domain containing 1 | 3.51032 |
| PRAF2 | PRA1 domain family, member 2 | 3.46106 |
| RXYLT1 | ribitol xylosyltransferase 1 | 3.18218 |
| STIMATE | STIM activating enhancer | 3.14822 |
| OXCT1 | 3-oxoacid CoA transferase 1 | 3.12814 |
| GPER1 | G protein-coupled estrogen receptor 1 | 3.04113 |
| MSRA | methionine sulfoxide reductase A | 3.01793 |
| LPAR2 | lysophosphatidic acid receptor 2 | 2.99816 |
| GAPDHS | glyceraldehyde-3-phosphate dehydrogenase, spermatogenic | 2.88217 |
| HMOX1 | heme oxygenase 1 | 2.8536 |
| DIPK1A | divergent protein kinase domain 1A | 2.8281 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 2.75778 |
| LCN2 | lipocalin 2 | 2.73522 |
| TERT | telomerase reverse transcriptase | 2.72722 |
| GHR | growth hormone receptor | 2.72095 |
| NPDC1 | neural proliferation, differentiation and control, 1 | 2.68313 |
| TICAM1 | toll-like receptor adaptor molecule 1 | 2.54584 |
| TUBA3C | tubulin, alpha 3c | 2.543 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 2.52479 |
| MSL1 | male-specific lethal 1 homolog (Drosophila) | 2.51997 |
| CDK2AP1 | cyclin-dependent kinase 2 associated protein 1 | 2.51462 |
| RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 | 2.50854 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 2.50028 |
| STXBP2 | syntaxin binding protein 2 | 2.47026 |
| ZPBP | zona pellucida binding protein | 2.43166 |
| NMU | neuromedin U | 2.40037 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 2.3851 |
| COL4A1 | collagen, type IV, alpha 1 | 2.34402 |
| KIFBP | kinesin family binding protein | 2.33139 |
| TCP11 | t-complex 11, testis-specific | 2.32634 |
| CAPN1 | calpain 1, (mu/I) large subunit | 2.32003 |
| ARL4C | ADP-ribosylation factor-like 4C | 2.29838 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | 2.29279 |
| CDC45 | cell division cycle 45 | 2.29055 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 2.28426 |
| EVL | Enah/Vasp-like | 2.26615 |
| NPY5R | neuropeptide Y receptor Y5 | 2.23767 |
| NT5M | 5',3'-nucleotidase, mitochondrial | 2.23384 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 2.22937 |
| LSP1 | lymphocyte-specific protein 1 | 2.22581 |
| RSU1 | Ras suppressor protein 1 | 2.22222 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 2.21697 |
| CLBA1 | clathrin binding box of aftiphilin containing 1 | 2.21636 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 2.19387 |
| MICALL1 | MICAL-like 1 | 2.19344 |
| SOCS4 | suppressor of cytokine signaling 4 | 2.18524 |
| ANKRD7 | ankyrin repeat domain 7 | 2.18101 |
| DENND2D | DENN/MADD domain containing 2D | 2.17222 |
| SNX7 | sorting nexin 7 | 2.15989 |
| MMP2 | matrix metallopeptidase 2 | 2.14847 |
| SLC25A31 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31 | 2.14249 |
| ENAH | enabled homolog (Drosophila) | 2.13589 |
| RPS26 | ribosomal protein S26 | 2.13498 |
| DDX43 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 | 2.13145 |
| CDK5R1 | cyclin-dependent kinase 5, regulatory subunit 1 (p35) | 2.12326 |
| NCK2 | NCK adaptor protein 2 | 2.10084 |
| SYNGR3 | synaptogyrin 3 | 2.09501 |
| DHX29 | DEAH (Asp-Glu-Ala-His) box polypeptide 29 | 2.08634 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 2.07949 |
| SHCBP1L | SHC SH2-domain binding protein 1-like | 2.07837 |
| CHN1 | chimerin 1 | 2.07477 |
| CR2 | complement component (3d/Epstein Barr virus) receptor 2 | 2.05864 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 2.05478 |
| FAM20B | family with sequence similarity 20, member B | 2.05008 |
| TEC | tec protein tyrosine kinase | 2.04944 |
| FETUB | fetuin B | 2.04265 |
| MYLK | myosin light chain kinase | 2.04261 |
| ADAMTSL4 | ADAMTS-like 4 | 2.04225 |
| GSTZ1 | glutathione S-transferase zeta 1 | 2.03472 |
| LOXL1 | lysyl oxidase-like 1 | 2.03158 |
| DDX4 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 | 2.02685 |
| NNT | nicotinamide nucleotide transhydrogenase | 2.02358 |
| COLQ | collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase | 2.02094 |
| MAST2 | microtubule associated serine/threonine kinase 2 | 2.01331 |
| ZFY | zinc finger protein, Y-linked | 2.01008 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -9.85962 |
| GTPBP8 | GTP-binding protein 8 (putative) | -6.91895 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -6.52755 |
| ZNF586 | zinc finger protein 586 | -6.27474 |
| IDH1 | isocitrate dehydrogenase 1 (NADP+), soluble | -5.38825 |
| MAPK13 | mitogen-activated protein kinase 13 | -5.03954 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -5.03757 |
| TRIB3 | tribbles pseudokinase 3 | -4.93358 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -4.6438 |
| HYOU1 | hypoxia up-regulated 1 | -4.41189 |
| LDHD | lactate dehydrogenase D | -4.35091 |
| PDZD2 | PDZ domain containing 2 | -4.04515 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -3.94514 |
| CCNB1 | cyclin B1 | -3.75448 |
| FASTKD5 | FAST kinase domains 5 | -3.67254 |
| TM9SF2 | transmembrane 9 superfamily member 2 | -3.5179 |
| DERA | deoxyribose-phosphate aldolase (putative) | -3.36222 |
| NCK1 | NCK adaptor protein 1 | -3.34793 |
| LOC124907782 | dual specificity protein phosphatase 22 | -3.30779 |
| ADI1 | acireductone dioxygenase 1 | -3.29152 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -3.24567 |
| INPP1 | inositol polyphosphate-1-phosphatase | -3.19483 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | -3.17666 |
| ABCF3 | ATP-binding cassette, sub-family F (GCN20), member 3 | -3.13773 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -3.02667 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | -3.00993 |
| KIF14 | kinesin family member 14 | -2.93377 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -2.89672 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -2.87056 |
| KDM3A | lysine (K)-specific demethylase 3A | -2.82017 |
| ISOC1 | isochorismatase domain containing 1 | -2.80919 |
| FGFR4 | fibroblast growth factor receptor 4 | -2.80857 |
| ZNF106 | zinc finger protein 106 | -2.80719 |
| PRKCD | protein kinase C, delta | -2.77766 |
| GID8 | GID complex subunit 8 | -2.61734 |
| RPIA | ribose 5-phosphate isomerase A | -2.5909 |
| ACAA1 | acetyl-CoA acyltransferase 1 | -2.58558 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) | -2.55253 |
| MFAP1 | microfibrillar-associated protein 1 | -2.48729 |
| RGS2 | regulator of G-protein signaling 2 | -2.47814 |
| MVP | major vault protein | -2.47313 |
| USP6NL | USP6 N-terminal like | -2.46484 |
| MRPS2 | mitochondrial ribosomal protein S2 | -2.46058 |
| ZDHHC6 | zinc finger, DHHC-type containing 6 | -2.45515 |
| TAF11 | TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa | -2.42801 |
| ANKRD10 | ankyrin repeat domain 10 | -2.4165 |
| HSD17B10 | hydroxysteroid (17-beta) dehydrogenase 10 | -2.41586 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | -2.41447 |
| XPO7 | exportin 7 | -2.39267 |
| RBM22 | RNA binding motif protein 22 | -2.38785 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -2.38067 |
| AKAP8 | A kinase (PRKA) anchor protein 8 | -2.36977 |
| PSMA3 | proteasome (prosome, macropain) subunit, alpha type, 3 | -2.3674 |
| TFF3 | trefoil factor 3 (intestinal) | -2.36136 |
| SMG8 | SMG8 nonsense mediated mRNA decay factor | -2.34036 |
| SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) | -2.30443 |
| TCEAL4 | transcription elongation factor A (SII)-like 4 | -2.2935 |
| CERS6 | ceramide synthase 6 | -2.29012 |
| ZW10 | zw10 kinetochore protein | -2.28145 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -2.27928 |
| EIF3J | eukaryotic translation initiation factor 3, subunit J | -2.26147 |
| COMMD3 | COMM domain containing 3 | -2.23708 |
| IKZF5 | IKAROS family zinc finger 5 (Pegasus) | -2.23241 |
| COG2 | component of oligomeric golgi complex 2 | -2.20483 |
| HAX1 | HCLS1 associated protein X-1 | -2.20162 |
| DUSP6 | dual specificity phosphatase 6 | -2.19467 |
| TYK2 | tyrosine kinase 2 | -2.17943 |
| DNAJA2 | DnaJ (Hsp40) homolog, subfamily A, member 2 | -2.17292 |
| EIF5 | eukaryotic translation initiation factor 5 | -2.16787 |
| THUMPD2 | THUMP domain containing 2 | -2.16494 |
| IRF9 | interferon regulatory factor 9 | -2.15483 |
| TLCD3A | TLC domain containing 3A | -2.14649 |
| ZNF761 | zinc finger protein 761 | -2.13372 |
| RPN1 | ribophorin I | -2.13126 |
| ZC2HC1A | zinc finger, C2HC-type containing 1A | -2.10057 |
| COPG1 | coatomer protein complex, subunit gamma 1 | -2.09629 |
| SELENOT | selenoprotein T | -2.08906 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -2.07797 |
| PEX11B | peroxisomal biogenesis factor 11 beta | -2.07088 |
| NANS | N-acetylneuraminic acid synthase | -2.06722 |
| PEG10 | paternally expressed 10 | -2.05233 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | -2.03905 |
| TNIP1 | TNFAIP3 interacting protein 1 | -2.03699 |
| RTCA | RNA 3'-terminal phosphate cyclase | -2.0312 |
| TCTN1 | tectonic family member 1 | -2.02709 |
| CCDC59 | coiled-coil domain containing 59 | -2.0258 |
| UTP14A | UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) | -2.02503 |
| TXNDC15 | thioredoxin domain containing 15 | -2.02433 |
| TRIB1 | tribbles pseudokinase 1 | -2.01392 |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 | -2.00019 |
