| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | iq 19.2 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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64 genes differentially expressed following the CRCGN010_HEPG2_24H:L14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 6.99453 |
| MAP7 | microtubule-associated protein 7 | 4.72244 |
| SQOR | sulfide quinone oxidoreductase | 4.51583 |
| EAPP | E2F-associated phosphoprotein | 4.22721 |
| CCDC92 | coiled-coil domain containing 92 | 3.92037 |
| DENND2D | DENN/MADD domain containing 2D | 3.8933 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 3.80888 |
| NOTCH1 | notch 1 | 3.77572 |
| HSPA1A | heat shock 70kDa protein 1A | 3.63946 |
| CSK | c-src tyrosine kinase | 3.63191 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 3.59157 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 3.36474 |
| LCN2 | lipocalin 2 | 3.26561 |
| UBQLN2 | ubiquilin 2 | 3.19656 |
| STIMATE | STIM activating enhancer | 3.08776 |
| CHMP6 | charged multivesicular body protein 6 | 2.95143 |
| STK10 | serine/threonine kinase 10 | 2.90325 |
| MAMLD1 | mastermind-like domain containing 1 | 2.89225 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 2.68045 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 2.60046 |
| KIF5C | kinesin family member 5C | 2.56108 |
| E2F2 | E2F transcription factor 2 | 2.53298 |
| GATA2 | GATA binding protein 2 | 2.52552 |
| ATP11B | ATPase, class VI, type 11B | 2.37216 |
| NPDC1 | neural proliferation, differentiation and control, 1 | 2.3509 |
| NFATC4 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 | 2.33304 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 2.21077 |
| BTBD1 | BTB (POZ) domain containing 1 | 2.20939 |
| TTC1 | tetratricopeptide repeat domain 1 | 2.15333 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | 2.11694 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) | 2.09796 |
| EDN1 | endothelin 1 | 2.06649 |
| WDR82 | WD repeat domain 82 | 2.00323 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -5.75747 |
| DNM1L | dynamin 1-like | -4.29806 |
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) | -4.26022 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -4.0827 |
| GOLT1B | golgi transport 1B | -3.59792 |
| LDHD | lactate dehydrogenase D | -3.53875 |
| UGDH | UDP-glucose 6-dehydrogenase | -3.43805 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -3.30019 |
| ZNF586 | zinc finger protein 586 | -3.23764 |
| CDC20 | cell division cycle 20 | -3.04879 |
| EIF5 | eukaryotic translation initiation factor 5 | -2.9626 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -2.8723 |
| CCNB1 | cyclin B1 | -2.71864 |
| PCNA | proliferating cell nuclear antigen | -2.70322 |
| LOC124907782 | dual specificity protein phosphatase 22 | -2.69115 |
| FAIM | Fas apoptotic inhibitory molecule | -2.56952 |
| HYOU1 | hypoxia up-regulated 1 | -2.51131 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) | -2.51018 |
| YME1L1 | YME1-like 1 ATPase | -2.45659 |
| XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble | -2.41964 |
| PPOX | protoporphyrinogen oxidase | -2.3704 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -2.36907 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -2.3216 |
| MAPK13 | mitogen-activated protein kinase 13 | -2.29548 |
| FGFR4 | fibroblast growth factor receptor 4 | -2.26195 |
| TAF2 | TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa | -2.26056 |
| SNX11 | sorting nexin 11 | -2.22137 |
| WASHC4 | WASH complex subunit 4 | -2.13233 |
| RFC2 | replication factor C (activator 1) 2, 40kDa | -2.09841 |
| VDAC1 | voltage-dependent anion channel 1 | -2.08076 |
| SULT1A2 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2 | -2.0634 |
