| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | iq 9.6 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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154 genes differentially expressed following the CRCGN010_HEPG2_24H:L15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit | 9.55963 |
| PPARG | peroxisome proliferator-activated receptor gamma | 9.37686 |
| MAP7 | microtubule-associated protein 7 | 7.37049 |
| ATP11B | ATPase, class VI, type 11B | 5.92956 |
| UBQLN2 | ubiquilin 2 | 5.24212 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 5.2108 |
| MEF2C | myocyte enhancer factor 2C | 4.73268 |
| ABHD6 | abhydrolase domain containing 6 | 4.44411 |
| CGRRF1 | cell growth regulator with ring finger domain 1 | 4.43088 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 4.42338 |
| EPHB2 | EPH receptor B2 | 4.36803 |
| TICAM1 | toll-like receptor adaptor molecule 1 | 4.12443 |
| CHMP6 | charged multivesicular body protein 6 | 4.07064 |
| RPL39L | ribosomal protein L39-like | 3.79535 |
| NSDHL | NAD(P) dependent steroid dehydrogenase-like | 3.66117 |
| KIF5C | kinesin family member 5C | 3.5281 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 3.47251 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 3.44438 |
| NPDC1 | neural proliferation, differentiation and control, 1 | 3.41114 |
| DENND2D | DENN/MADD domain containing 2D | 3.39037 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | 3.31543 |
| WDR7 | WD repeat domain 7 | 3.22406 |
| KDM5A | lysine (K)-specific demethylase 5A | 3.18399 |
| PRKCH | protein kinase C, eta | 3.1629 |
| CYB561 | cytochrome b561 | 3.15467 |
| LPAR2 | lysophosphatidic acid receptor 2 | 2.96585 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 2.8793 |
| FAM120C | family with sequence similarity 120C | 2.80741 |
| GHR | growth hormone receptor | 2.79124 |
| MBNL1 | muscleblind-like splicing regulator 1 | 2.61902 |
| CEP57 | centrosomal protein 57kDa | 2.60628 |
| TMEM47 | transmembrane protein 47 | 2.59661 |
| DDX42 | DEAD (Asp-Glu-Ala-Asp) box helicase 42 | 2.55576 |
| LOC122526780 | uncharacterized LOC122526780 | 2.54985 |
| VGLL4 | vestigial-like family member 4 | 2.54957 |
| TMEM94 | transmembrane protein 94 | 2.51129 |
| NOL11 | nucleolar protein 11 | 2.49184 |
| GLB1L2 | galactosidase, beta 1-like 2 | 2.48356 |
| GABPA | GA binding protein transcription factor, alpha subunit 60kDa | 2.47564 |
| SEC14L4 | SEC14-like 4 (S. cerevisiae) | 2.43023 |
| ELAC2 | elaC ribonuclease Z 2 | 2.4286 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 2.40066 |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 | 2.38074 |
| RAB21 | RAB21, member RAS oncogene family | 2.37004 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | 2.36223 |
| CA5A | carbonic anhydrase VA, mitochondrial | 2.34414 |
| NT5M | 5',3'-nucleotidase, mitochondrial | 2.32033 |
| ADAP1 | ArfGAP with dual PH domains 1 | 2.31507 |
| PGAP4 | post-GPI attachment to proteins GalNAc transferase 4 | 2.31276 |
| KBTBD11 | kelch repeat and BTB (POZ) domain containing 11 | 2.28668 |
| CDX1 | caudal type homeobox 1 | 2.26415 |
| NKX2-8 | NK2 homeobox 8 | 2.2553 |
| GTF2F2 | general transcription factor IIF, polypeptide 2, 30kDa | 2.25474 |
| VSX1 | visual system homeobox 1 | 2.25235 |
| AIRIM | AFG2 interacting ribosome maturation factor | 2.22236 |
| MTMR4 | myotubularin related protein 4 | 2.21937 |
| CLDN11 | claudin 11 | 2.20929 |
| CCL24 | chemokine (C-C motif) ligand 24 | 2.19727 |
| SAFB | scaffold attachment factor B | 2.19152 |
| CDC42BPB | CDC42 binding protein kinase beta (DMPK-like) | 2.18256 |
| COMMD8 | COMM domain containing 8 | 2.1263 |
| YEATS4 | YEATS domain containing 4 | 2.11761 |
| HHLA2 | HERV-H LTR-associating 2 | 2.11382 |
| ATOH1 | atonal homolog 1 (Drosophila) | 2.1085 |
| PLD2 | phospholipase D2 | 2.10348 |
| HAUS6 | HAUS augmin-like complex, subunit 6 | 2.09549 |
| TUBB6 | tubulin, beta 6 class V | 2.08147 |
| SLC33A1 | solute carrier family 33 (acetyl-CoA transporter), member 1 | 2.07637 |
| NRXN2 | neurexin 2 | 2.0646 |
| HTR5A | 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled | 2.05143 |
| SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 | 2.04428 |
| RNF146 | ring finger protein 146 | 2.03974 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | 2.03826 |
| SLC25A38 | solute carrier family 25, member 38 | 2.03705 |
| ECT2 | epithelial cell transforming 2 | 2.03599 |
| KRR1 | KRR1, small subunit (SSU) processome component, homolog (yeast) | 2.03164 |
| RRAGC | Ras-related GTP binding C | 2.02984 |
| GBA3 | glucosidase, beta, acid 3 (gene/pseudogene) | 2.02826 |
| CCL15 | chemokine (C-C motif) ligand 15 | 2.01935 |
| PPFIA2 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2 | 2.0144 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 2.00779 |
| MYL5 | myosin, light chain 5, regulatory | 2.00245 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -6.50463 |
| GNAS | GNAS complex locus | -6.3418 |
| MRPS16 | mitochondrial ribosomal protein S16 | -5.59572 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -5.24701 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -5.14171 |
| LDHD | lactate dehydrogenase D | -5.07829 |
| POLR2I | polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa | -5.03885 |
| PCNA | proliferating cell nuclear antigen | -4.94274 |
| ZW10 | zw10 kinetochore protein | -4.88697 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -4.76072 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | -4.59799 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -4.5846 |
| GOLT1B | golgi transport 1B | -4.57138 |
| MRPS2 | mitochondrial ribosomal protein S2 | -4.57059 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -4.45656 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -4.42411 |
| KDM3A | lysine (K)-specific demethylase 3A | -4.36702 |
| LYPLA1 | lysophospholipase I | -4.11021 |
| MAPK13 | mitogen-activated protein kinase 13 | -4.05067 |
| CHMP4B | charged multivesicular body protein 4B | -3.83853 |
| PEG10 | paternally expressed 10 | -3.73664 |
| PSMD8 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 | -3.49343 |
| UBE3C | ubiquitin protein ligase E3C | -3.42967 |
| YME1L1 | YME1-like 1 ATPase | -3.37776 |
| ZNF586 | zinc finger protein 586 | -3.35049 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -3.11768 |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) | -3.11329 |
| ICAM3 | intercellular adhesion molecule 3 | -3.08692 |
| TES | testin LIM domain protein | -2.96811 |
| NR2F6 | nuclear receptor subfamily 2, group F, member 6 | -2.85757 |
| COX6B1 | cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) | -2.71083 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -2.63259 |
| NDUFB6 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa | -2.54204 |
| FGG | fibrinogen gamma chain | -2.53464 |
| TMEM147 | transmembrane protein 147 | -2.50287 |
| LAGE3 | L antigen family, member 3 | -2.49069 |
| CIRBP | cold inducible RNA binding protein | -2.48806 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | -2.41997 |
| CIAPIN1 | cytokine induced apoptosis inhibitor 1 | -2.41048 |
| TCTN1 | tectonic family member 1 | -2.38356 |
| ERCC1 | excision repair cross-complementation group 1 | -2.36 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -2.3387 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase | -2.32593 |
| LDHA | lactate dehydrogenase A | -2.32336 |
| NDUFS7 | NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) | -2.31743 |
| TM9SF4 | transmembrane 9 superfamily protein member 4 | -2.2978 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -2.27631 |
| TIMM10B | translocase of inner mitochondrial membrane 10 homolog B (yeast) | -2.26679 |
| DGAT1 | diacylglycerol O-acyltransferase 1 | -2.21361 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -2.19782 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | -2.17033 |
| NDUFB4 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa | -2.15725 |
| APBB3 | amyloid beta (A4) precursor protein-binding, family B, member 3 | -2.14369 |
| NDUFB3 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa | -2.14046 |
| PDGFRB | platelet-derived growth factor receptor, beta polypeptide | -2.13997 |
| STX5 | syntaxin 5 | -2.13878 |
| CALU | calumenin | -2.10635 |
| CSAD | cysteine sulfinic acid decarboxylase | -2.10007 |
| PDE8B | phosphodiesterase 8B | -2.09264 |
| NANOS3 | nanos homolog 3 (Drosophila) | -2.07946 |
| CAPNS1 | calpain, small subunit 1 | -2.06959 |
| UQCRFS1 | ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 | -2.06825 |
| YIF1A | Yip1 interacting factor homolog A (S. cerevisiae) | -2.06615 |
| ELOVL2 | ELOVL fatty acid elongase 2 | -2.0474 |
| TRMT2B | tRNA methyltransferase 2 homolog B (S. cerevisiae) | -2.03789 |
| PRKRA | protein kinase, interferon-inducible double stranded RNA dependent activator | -2.03246 |
| PIGT | phosphatidylinositol glycan anchor biosynthesis, class T | -2.02647 |
| NHP2 | NHP2 ribonucleoprotein | -2.02601 |
| PLBD1 | phospholipase B domain containing 1 | -2.0231 |
| NDST2 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 | -2.01741 |
| TMEM123 | transmembrane protein 123 | -2.01441 |
| ADI1 | acireductone dioxygenase 1 | -2.01165 |
