CRCGN010_HEPG2_24H:L16 Gene Set
Genes
51 genes differentially expressed following the CRCGN010_HEPG2_24H:L16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
STIMATE
|
STIM activating enhancer
|
6.72963
|
|
ZFP36
|
ZFP36 ring finger protein
|
4.68115
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
4.26533
|
|
CCDC92
|
coiled-coil domain containing 92
|
4.09461
|
|
CCNF
|
cyclin F
|
3.85734
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
3.81697
|
|
KIFBP
|
kinesin family binding protein
|
3.73284
|
|
NOTCH1
|
notch 1
|
3.34155
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
3.15232
|
|
RELB
|
v-rel avian reticuloendotheliosis viral oncogene homolog B
|
3.03275
|
|
CEP57
|
centrosomal protein 57kDa
|
2.95248
|
|
FZD7
|
frizzled class receptor 7
|
2.88383
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
2.86144
|
|
SOCS2
|
suppressor of cytokine signaling 2
|
2.70338
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
2.68749
|
|
PRKCH
|
protein kinase C, eta
|
2.64685
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
2.58868
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
2.54224
|
|
CEBPD
|
CCAAT/enhancer binding protein (C/EBP), delta
|
2.5402
|
|
RXYLT1
|
ribitol xylosyltransferase 1
|
2.38814
|
|
HYOU1
|
hypoxia up-regulated 1
|
2.38211
|
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
2.36856
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.35738
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.3506
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.21799
|
|
AXIN1
|
axin 1
|
2.16728
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
2.11662
|
|
RALGDS
|
ral guanine nucleotide dissociation stimulator
|
2.06421
|
|
TIMM17B
|
translocase of inner mitochondrial membrane 17 homolog B (yeast)
|
2.0481
|
|
COQ6
|
coenzyme Q6 monooxygenase
|
2.00041
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CCNB2
|
cyclin B2
|
-9.35576
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-7.04081
|
|
ZNF586
|
zinc finger protein 586
|
-5.52238
|
|
TLCD3A
|
TLC domain containing 3A
|
-4.57209
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-4.34548
|
|
UGDH
|
UDP-glucose 6-dehydrogenase
|
-3.47141
|
|
PCNA
|
proliferating cell nuclear antigen
|
-3.45032
|
|
LOC124907782
|
dual specificity protein phosphatase 22
|
-3.43419
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-3.11591
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-3.06147
|
|
CD320
|
CD320 molecule
|
-2.90375
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.85203
|
|
NR2F6
|
nuclear receptor subfamily 2, group F, member 6
|
-2.64094
|
|
FAIM
|
Fas apoptotic inhibitory molecule
|
-2.59983
|
|
YME1L1
|
YME1-like 1 ATPase
|
-2.58096
|
|
DUSP6
|
dual specificity phosphatase 6
|
-2.33334
|
|
MACF1
|
microtubule-actin crosslinking factor 1
|
-2.27477
|
|
RRP12
|
ribosomal RNA processing 12 homolog (S. cerevisiae)
|
-2.27188
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.15383
|
|
FAM53C
|
family with sequence similarity 53, member C
|
-2.04006
|
|
MRPS30
|
mitochondrial ribosomal protein S30
|
-2.01188
|
